Pedro J. Llanos, Kristina Andrijauskaite, Vijay V. Duraisamy, Francisco Pastrana, Erik L. Seedhouse, Sathya Gangadharan, Leonid Bunegin and Mariel Rico
In early 2016, the Department of Applied Aviation Sciences (AAS) at the Embry-Riddle Aeronautical University (ERAU) was granted a suborbitalflight opportunity to work on a Science, Technology, Engineering, and Mathematics (STEM) research project. The Spaceflight Operations team in the AAS department was already developing other suborbital payloads as part of the Arete STEM Project (ARETE) to demonstrate joint commercial spaceflight activities. The main aim of this research was to investigate the effect of microgravity on T-cells and to
prepare scientific payloads to conduct suborbital space research is still lacking.
Here, we provide findings on how performing feasibility studies lead to new insights on cells behavior and therefore influence the modifications of scientific payload design. More specifically, we exposed murine T-cells, Lewis lung carcinoma cells (LLC), breast cancer cells MCF7, and colon cancer cells HCT116 to thermal and vibration conditions, similar to those experienced during the suborbitalflight. Although vibration testing is encouraged by the flight provider, it was not