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Challenges of ERAU’s First Suborbital Flight Aboard Blue Origin’s New Shepard M7 for the Cell Research Experiment In Microgravity (CRExIM)

Introduction In early 2016, the Department of Applied Aviation Sciences (AAS) at the Embry-Riddle Aeronautical University (ERAU) was granted a suborbital flight opportunity to work on a Science, Technology, Engineering, and Mathematics (STEM) research project. The Spaceflight Operations team in the AAS department was already developing other suborbital payloads as part of the Arete STEM Project (ARETE) to demonstrate joint commercial spaceflight activities. The main aim of this research was to investigate the effect of microgravity on T-cells and to

Open access
Investigation of Murine T-Cells and Cancer Cells under Thermal Stressors and 2D Slow Rotating System Effects as a Testbed for Suborbital Flights

prepare scientific payloads to conduct suborbital space research is still lacking. Here, we provide findings on how performing feasibility studies lead to new insights on cells behavior and therefore influence the modifications of scientific payload design. More specifically, we exposed murine T-cells, Lewis lung carcinoma cells (LLC), breast cancer cells MCF7, and colon cancer cells HCT116 to thermal and vibration conditions, similar to those experienced during the suborbital flight. Although vibration testing is encouraged by the flight provider, it was not

Open access