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Abstract

The fact that companies are constantly subjected to changes creates challenges connected with constant learning and acquiring knowledge. Companies are forced to act in accordance with the generative strategy. Besides realizing the traditional tasks of production or service, companies need to acquire and process knowledge and apply it in practice. The consequence of these changes is the transformation of contemporary enterprises into knowledge-based organizations, with managers increasingly recognizing the role and importance of the concept of knowledge management in creating enterprises competitiveness. The main aim of the article is identification of knowledge management in production enterprises.

The Development of Production Management Concepts

The aim of this paper is the analysis of contemporary concepts used in production management in relation to the paradigms which accompanied their appearance and development. The first chapter contains a definition of the term 'paradigm', discusses the importance of the paradigms for the development of a scientific approach to management and lists examples of paradigms relevant to production management. In the second chapter such management concepts as LM, Kaizen, TOC, TQM, TPM, Six Sigma and BPR are presented, along with their respective old and new paradigms, main goals, fundamental rules and tools (methods and techniques). Some less popular concepts are also dealt with. The last chapter is devoted to an analysis of interactions between the analyzed concepts, with an emphasis on their mutual compatibility and complementarity, which can be of benefit in the process of their implementation.

Abstract

Cannabinoids impact human body by binding to cannabinoids receptors (CB1 and CB2). The two main phytocannabinoids are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC interacts with CB1 receptors occurring in central nervous system and is responsible for psychoactive properties of marijuana. CBD has low affinity to CB1 receptor, has no psychoactive characteristics and its medical applications can be wider. CB receptors are part of a complex machinery involved in regulation of many physiological processes – endocannabinoid system. Cannabinoids have found some applications in palliative medicine, but there are many reports concerning their anticancer affects. Agonists of CB1 receptors stimulate accumulation of ceramides in cancer cells, stress of endoplasmic reticulum (ER stress) and, in turn, apoptosis. Effects of cannabinoids showing low affinity to CB receptors is mediated probably by induction of reactive oxygen species production. Knowledge of antitumor activity of cannabinoids is still based only on preclinical studies and there is a necessity to conduct more experiments to assess the real potential of these compounds.

for their impact on propane curing efficiency. The resulting management system has resulted in drastic documented reductions in propane use. Dr. Gooden’s studies on curing efficiency have had a huge impact on producer profits and the viability of the South Carolina tobacco industry. Producers understand the impact of his recommendations and look to him for guidance in all aspects of production knowledge acquired through a lifetime of dedication to the industry and farmers. The success of the tobacco industry rests on the quality and integrity of our leaf. With Dr

://dx.doi.org/10.2307%2F259373 Roblek, M., Zajec, M. & Kern, T. (2011). The Lack of Knowledge? Change the Way you Work , Proceedings of the Forty-Fourth Hawaii International Conference on System Sciences HICSS-44, Kauai, HI. Los Alamitos, CA: IEEE Computer Society Press. Roblek, M. & Zajec, M. (2012). ETO Production knowledge based reverse engineering , 31. International Conference on Organizational Science Development. Quality. Innovation. Future. Portorož, 2012, 1022-1030. Russel Records, L. (2005). The Fusion of Process and Knowledge Management . Retrieved July 25, 2013

, 2005 , p. 5; Bogliacino et al., 2012 , p. 57]. According to Albulescu [2011, p. 29] , countries that realize an innovative model of economic growth obtain high competitive positions on the international arena. It is possible due to the use of the latest technological achievements and the production of highest quality products. As a result, the main source of competitive position growth is the technical and production knowledge contained in high-tech products [Turkowski, p. 94]. In developed post-industrial economies, the high-tech sector is included in areas with

utilisation is an important operational metric for businesses, and also a key economic indicator when applied to aggregate productive capacity. KPI 4 is a widely used performance indicator in manufacturing industries around the world. It is a measure of asset or equipment utilisation. OEE is indicated by the product of the availability index, performance index and the quality index. The first group adopts relevant industry and production knowledge and experience, operations management knowledge, IT skills, project management knowledge, maths and statistics knowledge etc