Katarina Stavrikj, Sonja Peova, Aleksandar Petlickovski, Irena Topuzovska and Mirko Spiroski
referred to a pediatric immunization clinic on account of egg allergy. Human Vaccines. 2005;1:3:118-122.
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Kauffman F and the posgenome respiratory epidemiology grup. Post-genome respiratory epidemiology: a multidisciplinary challenge
Hebatallah Ahmed Nasser, Nermeen Zakaria Abuel Ezz, Heidi Mohamed Abdel-Mageed and Rasha Ali Radwan
). In addition to infertility, PCOS is associated with several metabolic disorders such as obesity ( 5 ), insulin resistance (IR) ( 6 ), dyslipidemia ( 7 ), increased levels of inflammatory markers, with consequent increased risk of developing Type 2 diabetes and cardiovascular disorders among other serious disorders ( 7 , 8 , 9 ).
Meanwhile, asthma is a complex and chronic in ammatory disorder of the airways with local and systemic in ammation. It is characterized by a T helper cell 2 (Th2)-immune response, resulting in increased total immunoglobulin E (IgE
Ali Khosravi, Mahnaz Fatahinia, Hojjatollah Shokri and Mohammad Yadegari
Johansson SGO, Haahtela T. World allergy organization guidelines for prevention of allergy and allergic asthma. Int Arch Allergy Immunol 2004;135:83-92.
Yssel H, Abbal C, Pène J, Bousquet J. The role of IgE in asthma. Clin Exp Allergy 1998;28(Suppl 5):104-9.
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Horner WE, Helbling A, Salvaggio JE
Romuald Olszański, Maciej Konarski and Piotr Siermontowski
The paper discusses the treatment results of ten patients with severe atopic dermatitis (AD) who did not respond to standard pharmacotherapy and underwent hyperbaric oxygen therapy (HBOT). Each patient was subject to 10 oxygen exposures at pO2 2.5 ATA (~ 250 kPa) with the duration time of 60 minutes. In the period of implementation of the hyperbaric procedures the general treatment plan was suspended for all patients while maintaining typical local treatment. Clinical evaluation was performed in the study group as well as determination of levels of immunoglobulins: IgA, IgG, IgM and IgE and C3 and C4 complement. All patients indicated clinical improvement and a decreased IgE immunoglobulin and complement C3 level upon the completion of the exposure cycle. Taking into account the authors’ own observations and data from literature, an overall improvement in the clinical status and a decrease in the level of immunoglobulin E and C3 complement following a cycle of exposures may be indicative of an immunomodulating HBOT effect on AD, whereas hyperbaric oxygenation may constitute a therapeutic option for some patients with AD, especially those exhibiting a poor response to standard treatment.
Luljeta Ahmetaj, Fatime Kokollari and Violeta Lokaj
Prevalence of Aspirin-Induced Asthma in Certain Group of Kosovo Population and its Presentation
Background. Aspirin-induced asthma (AIA) is characterized by onset of asthma attack 30 minutes to 3 hours after ingestion of aspirin or NSAIDs (Non steroid antiinflammatory drugs). The typical reaction may be accompanied by intense rhinorhea, periorbital edema with conjunctival irritation and facial flushing. Often, at physical examination, nasal polyposis and serum eosinophilia are notable.
Aim: The aim of this study is to identify the behavior of aspirin induced asthma in a certain group of Kosovo population, in terms of age and its presentation.
Material and methods. At the University Hospital Centre in Prishtina, 172 adult patients with asthma were diagnosed, while 16 (9.3 %) of them were with aspirininduced asthma (f/m=12/4).
Results. The average age was 40.2 years. Nine of them showed triad of symptoms (aspirin-intolerance, asthma, nasal polyposis) while 7 (43.7%) showed tetrad of symptoms (aspirin-intolerance, asthma, nasal polyposis, and sinusitis). Total IgE levels were increased only in 3 patients (18.8%), while eosinophilia was increased only in 8 (50%) of the patients. The skin prick test with standard set of inhalant allergens was positive only in 3 patients (18.8%). There was no correlation between in vitro and in vivo tests.
Conclusion. Since there is no reliable in vitro test for the diagnosis of aspirin sensitivity, definitive diagnosis requires an oral or nasal aspirin challenge, which needs to be performed in a hospital.
Fabrizio Bruschi, Barbara Castagna, Francesca Mori-Ubaldini, Barbara Pinto, Francesco Costa and Ferruccio Bonino
picture ranges from being asymptomatic to requiring emergency room care. These clinical reactions correspond to the worm invasion of the gastrointestinal mucosae and submucosae, causing initially a hemorrhagic lesion, then inducing the formation of a pathognomonic eosinophilic phlegmon. In addition, IgE-mediated allergic reactions are often reported, as the result of a sensitization to a range of allergenic proteins. However, some patients develop simultaneously both the gastrointestinal and the allergic syndrome after ingesting living parasites. This condition would be
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KHABIRI, A.R., BAGHERI, F., ASSMAR, M., SIAVASHI, M.R. (2006): Analysis of specific IgE and IgG subclass antibodies for diagnosis of Echinococcus
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van Och FMM, Vandebriel RJ, De Jong WH, van Loveren