Aysan Mohammad Namdar, Mohammad Mohammadzadeh, Murat Okutan and Asghar Mesbahi
for Research on Cancer.
 Jemal A, Siegel R, Ward E, et al . Cancer statistics, 2007. CA Cancer J Clin. 2007;57:43-66.
 NCCN Clinical Practice Guidelines in Oncology. Breast cancer. ver.2. 2016. https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf : 2017.
 Wang SA, Rahemtullah A, Faquin WC, et al . Hodgkin’slymphoma of the thyroid: a clinicopathologic study of five cases and review of the literature. Mod Pathol. 2005;18(12):1577-1584.
 Alterio D, Jereczek-Fossa BA, Franchi B, et al . Thyroid disorders in patients
Alina Tănase, C. Tomuleasa, Alexandra Mărculescu, A. Bardaş, Anca Coliţă and Ş.O. Ciurea
Hodgkin’s disease with MOPP, ABVD, or MOPP alternating with ABVD. N Engl J Med. 1992; 327(21):1478-84.
7. DIEHL V., FRANKLIN J., PFEUNDSCHUCH M., LATHAN B., PAULUS U., HASENCLEVER D., et al. Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin’s disease. N Engl J Med. 2003; 348(24):2386-95.
8. SANTORO A., MAGAGNOLI M., SPINA M., PINOTTI G., SIRACUSANO L., MICHIELI M., et al. Ifosfamide, gemcitabine, and vinorelbine: a new induction regimen for refractory and relapsed Hodgkin’slymphoma
Chayapol Somboonyosdech, Supeecha Wittayalertpanya, Udomsak Bunworasate and Wacharee Limpanasithikul
1. Zhong Y. Non-Hogkin’s lymphoma: what primary care professionals need to know. J Nurse Pract. 2006; 2:309-15.
2. Hennessy BT, Hanrahan EO, Daly PA. Non-Hodgkin lymphoma: an update. The Lancet Oncol. 2004; 5: 341-53.
3. Lu P. Staging and classification of lymphoma. Semin Nucl Med. 2005; 35:160-4.
4. Sacchi S, Federico M, Dastoli G, Fiorani C, Vinci G, Clo‘ V, et al. Treatment of B-cell non-Hodgkin’slymphoma with anti CD 20 monoclonal antibody Rituximab. Crit Rev Oncol Hematol. 2001
Rumyana Yankova, Magdalina Gyurova and Donka Brambarova
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29. Pereira CM, Lopes AM, Meneghini AJ, Silva AF, Botelho TdeL. Oral diffuse B-cell non-Hodgkin’slymphoma associated to Gorlin-Goltz syndrome: a
1 Chinese Society of Hepatology of Chinese Medical Association, Chinese Society of Infectious Diseases of Chinese Medical Association. The Guideline of Prevention and Treatment for Chronic Hepatitis B. Chinese Journal of Internal Medicine, 2006, 45(2):162-170.
2 Chen Y, Xie Q, Shen Z. Reactivation of HBV Related to Treatment of Malignant Lymphoma. Journal of Internal Medicine Concepts & Practice, 2007, 2(1):8-12.
3 Zheng R, Qin F, Zhai Y, et al . HBV Infection and Chemotherapy of Non-Hodgkin’sLymphoma. The Practical Journal of
Gautam Rawal, Raj Kumar, Sankalp Yadav and Amrita Singh
A rare complication associated with the Hodgkin’s lymphoma is the occurrence of persistent or recurrent hypoglycemia. Although few cases have been reported in the literature, describing its pathophysiology to be multifactorial, it is difficult to determine the exact cause. We present the case of a 26 year old patient diagnosed with Hodgkin’s lymphoma who developed recurrent episodes of hypoglycemia and also discuss the various causes for its pathogenesis. In this case the serum insulin and C-peptide levels were found to be low, suggesting the presence of insulin like growth factors (IGF) secreted by the cancer cells. Also, we performed a18F-2-fluoro-2-deoxy-d-glucose positron emission tomography that showed a massive tumor load. The published reports in literature have similary suggested the presence of IGF or auto-antibodies secreted by the tumor cells and also the Warburg effect in patients with high tumor load. Further research is required to clearly diagnose and define the exact etiopathogenesis of the hypoglycemia occurring in a patient with Hodgkin’s lymphoma.
Mădălina Ioana Moisi, Cosmin Vesa, Larisa Roşan, Vâtcă Liliana, Babeş Katalin and Mircea Ioachim Popescu
We present the case of a 36-year-old patient admitted with dyspnea, subjective sensation of edema of the cervical region, and precordial pain with sudden onset. Pathological antecedents revealed a respiratory intercourse three weeks ago. Laboratory findings indicated an inflammatory syndrome accompanied by hypoproteinemia. We performed an echocardiographic examination which revealed important pericardial effusion and swinging heart aspect with diastolic collapse of the right atrium and ventricle. According to the existing guidelines pericardiocentesis was immediately required. The hemorrhagic pericardial effusion had an intense positive Rivalta reaction with frequent macrophages and malignant atypical cells. The next step was a full-body computer tomography scan, which revealed an expansive mediastinal mass, invading the upper cava vein and pericardium, with mediastinal adenopathy. A biopsy was performed and the pathology examination concluded there was a classical Hodgkin’s lymphoma nodular sclerosis type. Finally the patient was directed to oncology department.
Introduction. Non-Hodgkin lymphomas (NHL) are among the most frequent types of cancer linked with the lymphatic system. The disease, if not diagnosed or treated, may lead to serious health complications and/or death.
Aim. The purpose of the work is to evaluate the level of knowledge of nursing staff about NHL.
Material and methods. There were 100 members of nursing staff aged from 24 to 56 participating in the study. The research method was a diagnostic survey but the measuring tool was an anonymous author’s questionnaire which comprised 25 closed, single-choice questions and 2 filtering questions.
Results. Among the respondents, 48% work at the Clinical Haematology/Oncology Ward, while the remaining 52% work in other wards. The question: “Is it possible for the NHL to be located outside the lymphatic system?”, 55% of respondents responded with an affirmative, 23% with a negative, 22% did not know the answer. Among the respondents, 100% stated that their employers do not designate any financial assets to train medical personnel with respect to expanding their knowledge about non-Hodgkin lymphomas. As many as 46% of respondents expand their knowledge through self-study using their own means. According to the National Cancer Registry, in 2014 there were 874 incidents and 236 deaths noted among men and 862 incidents and 235 deaths among women, linked with the diffused NHL. Comparing the data of the National Cancer Registry with the previous years, we can observe an increasing trend of morbidity and mortality, linked with the NHL. For example, in 2006 there were a total 1207 cases and 315 deaths linked with the diffused NHL.
Conclusions. Results show that the respondents’ awareness with regard to NHL is limited. Employers do not finance NHL training, which may affect the low level of knowledge. NHL patient hospitalization is a long-term process requiring expenses and effort on the side of medical personnel. Nursing and health education are necessary elements of the therapeutic process of an NHL patient.
Ola Khorshed, Amany Helal, Yasser A. Sallam, Asmaa Salama and Mohammad Amin
1] Harris NL (2001) Mature B-cell neoplasms In: WHO Classification of Tumors: Pathology and Genetics of Tumors of Hematopoietic and Lymphoid Tissues, Jaffe EJ, Harris NL, Stein H et al. (eds), Lyon, France, IARC Press, p 121- 126
 Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E, et al. Cancer statistics, 2004. CA Cancer J Clin 2004;54:8-29
 Groves FD, Linet MS, Travis LB, et al (2000) Cancer surveillance series: Non-Hodgkin’slymphoma incidence by histologic subtype in the United
Kursat Okuyucu, Sukru Ozaydın, Engin Alagoz, Gokhan Ozgur, Semra Ince, Fahrettin Guven Oysul, Ozlem Ozmen, Murat Tuncel, Mustafa Ozturk and Nuri Arslan
Non-Hodgkin’slymphomas (NHLs) arising from the tissues other than primary lymphatic organs (lymph nodes, bone marrow, spleen, thymus and Waldeyer’s ring of pharyngeal lymphatics) are named primary extranodal lymphoma (PEL). 1 , 2 Although PEL can arise in almost every organ, gastrointestinal tract is the most frequently involved localization. Its incidence accounts for 30–40% of all extranodal cases in hospital and population-based series published so far. The most common locations in gastrointestinal system (GIS) are stomach (50–60%) and