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samples from urban and rural occupational environments in Croatia. Arh Hig Rada Toksikol 2005;56:327-32. Gross I, Heinrich J, Fahlbusch B, Jäger L, Bischoff W, Wichmann HE. Indoor determinants of Der p 1 and Der f 1 concentrations in house dust are different. Clin Exp Allergy 2000;30:376-82. de Andrade D, Birnbaum J, Lanteaume A, Izard JL, Corget P, Artillan MF, Toumi M, Vervloet D, Charpin D. Housing and house-dust mites. Allergy 1995;50:142-6. van Strien RT, Gehring U, Belanger K, Triche E, Gent J, Bracken MB, Leaderer BP. The influence of air conditioning

Allergy Clin Immunol 1997;100:S2-S24. Leaderer BP, Belanger K, Triche E, Holford T, Gold DR, Kim Y, Jankun T, Ren P, McSharry J, Platts-Mills TA, Chapman MD, Bracken MB. Dust mite, cockroach, cat, and dog allergen concentrations in homes of asthmatic children in the northeastern United States: impact of socioeconomic factors and population density. Environ Health Perspect 2002;110(Suppl 4):419-25. Arlian LG. Arthropod allergens and human health. Annu Rev Entomol 2002;47:395-433. De Lucca S, Sporik R, O'Meara TJ, Tovey ER. Mite allergen (Der p 1) is not only carried on

, Fitzharris P. The effects of temperature and buffer on the extraction of Der p 1 from dust. J Allergy Clin Immunol 1997;100:580. 9. Siebers R, Rains N, Fitzharris P, Crane J. The worldwide external Der p 1 quality control program: results from round three. In: Siebers R, Fitzharris P, Cunningham M, Crane J, editors. Mites, asthma and domestic design III. Wellington: Wellington Asthma Research Group; 1997. p. 21-6. 10. Prester Lj, Brčić Karačonji I, Macan J. Determination of mite allergens in house dust using the enzyme immunoassay. Arh Hig Rada Toksikol 2007;58:413-9. 11

. Age structure and dynamics of house dust mite populations. Exp Appl Acarol 1992;16:49-74. Chapman MD. Guanine-an adequate index of mite exposure? Allergy 1993;48:301-2. Luczynska CM, Arruda LK, Platts-Mills TAE, Miller JD, Lopez M, Chapman MD. A two-site monoclonal antibody ELISA for the quantification of the major Dermatophagoides spp. allergens Der p 1 and Der f 1. J Immunol Methods 1989;118:227-35. Prester L, Brčić Karačonji I, Macan J. Determination of mite allergens in house dust using the enzyme immunoassay. Arh Hig Rada Toksikol 2007;58:413-9. Tsay A

References 1. Prester L, Kovačić, Macan J. Comparison of buffers for extraction of mite allergen Der p 1 from dust. Arh Hig Rada Toksikol 2012;63:293-300. 2. Siebers R, Luey B, Crane J, Fitzharris P. The effects of temperature and buffer on the extraction of Der p 1 from dust. J Allergy Clin Immunol 1997;100:580. 3. Siebers R, Rains N, Fitzharris P, Crane J. The worldwide external Der p 1 quality control program: results from round three. In: Siebers R, Fitzharris P, Cunningham M, Crane J, editors. Mites, asthma and domestic design III. Wellington (NZ); Asthma

Clin Immunol 1995;98:64-72. Marks GB, Tovey EU, Toelle BG, Wachinger S, Peat JK, Woolcock AJ. Mite allergen (Der p 1) concentration in houses and its relation to severity of asthma in a population of Sydney schoolchildren. J Allergy Clin Immunol 1995;96:441-8. Platt-Mills TAE, Hhayden ML, Chapman MD, Wilkins SR. Seasonal variation in dust mite and grass pollen allergens in dust from the houses of patients with asthma. J Aller Clin Immunol 1086;79:781-91. Grad R. Risk of asthma in children with exposure to mite and cat allergens. Lancet 2001;356:1369-70. Ownby

, Anua S, Semple S, Dick F, Devereux G. The ‘take home’ burden of workplace sensitizers: Flour contamintaion in bakers’ families. Environ Int 2012;46:44-9. doi: 10.1016/j.envint.2012.04.014. 8. Tagiyeva N, Devereux G, Semple S, Sherrif A, Henderson J, Elias P,Ayres JG. Parental occupation is a risk factor for childhood wheeze and asthma. Eur Respir J 2010;35:987-93. doi: 10.1183/09031936.00050009 9. Barber D, Pernas M, Chamorro M, Carreira J, Artega C, Sanchez-Monge R, Polo F, Salced G. Specific depletion of the house dust mite allergen Der p 1 by cereal flour

disease. Drug News & Perspectives , 21 (7), 369-381. https://doi.org/10.1358/dnp.2008.21.7.1255294 Wang, D. Q., Shen, Y. Y., Xu, J. H., & Tang, H. (2016). Effect of the house dust mite allergen Der p 1 on tryptase release from human mast cells. Genetics and Molecular Research , 15 (2), 15028284. https://doi.org/10.4238/gmr.15028284 Wang, J., Zhang, H., Zheng, W., Xie, H., Yan, H., Lin, X., He, S. (2016). Correlation of IL-18 with tryptase in atopic asthma and induction of mast cell accumulation by IL-18. Mediators of Inflammation , 2016 , 4743176. https

. House dust mite Der p 1 effects on sininasal epithelial tight junction. Int Forum Allergy Rhinol 2013;3:630-5. doi: 10.1002/alr.21168 5. Wise SK, Laury AM, Katz EH, Den Beste KA, Parkos CA, Nusrat A. IL-4 and IL-13 compromise the sinonasal epithelial abrrier and perturb intercellular junction protein expression. Int Forum Allergy Rhinol 2014;4:361-70. 6. De Corso E, Baroni S, Romitelli F, Luca L, Di Nardo W, Passali GC, Paludetti G. Nasal lavage CCL24 levels correlate with eosinophil trafficking and symptoms in chronic sinonasal eosinophilic inflammation. Rhinology