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A superior preparation method for daidzein-hydroxypropyl-β-cyclodextrin complexes with improved solubility and dissolution: Supercritical fluid process

References 1. S. Soumyakrishnan, T. Divya, S. Kalayarasan, N. Sriram and G. Sudhandiran, Daidzein exhibits anti-fibrotic effect by reducing the expressions of Proteinase activated receptor 2 and TGFbeta1/ Smad mediated inflammation and apoptosis in Bleomycin-induced experimental pulmonary fibrosis, Biochimie 103 (2014) 23-36; DOI: 10.1016/j.biochi.2014.04.005. 2. B. Pahari, B. Sengupta, S. Chakraborty, B. Thomas, D. McGowan and P. K. Sengupta, Contrasting binding of fisetin and daidzein in gamma

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Effects of daidzein on testosterone secretion in cultured immature mouse testis

References 1. Zhang LP, Cui S. Effects of daidzein on testosterone synthesis and secretion in cultured mouse Leydig cells. Asian-Aust J Anim Sci. 2009; 22:618-25. 2. Wang G, Zhang X, Han Z, Liu Z, Liu W. Effects of daidzein on body weight gain, serum IGF-I level and cellular immune function in intact male piglets. Asian- Aust J Anim Sci. 2002; 15:1066-70. 3. Han D, Tachibana H, Yamada K. Inhibition of environmental estrogen-induced proliferation of human breast carcinoma MCF-7 cells by flavonoids. In Vitro Cell

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Immuno-histomorphometric and -fluorescent characteristics of GH cells after treatment with genistein or daidzein in an animal model of andropause

:193-199. 13. Picherit C, Coxam V, Benne tau-Pelissero C, Kati-Coulibaly S, Davicco MJ, Lebecque P, Barlet JP: Daidzein is more effi cient than genistein in preventing ovariectomy-induced bone loss in rats. J Nutr 2000, 130:1675-1681. 14. Ajdzanovic VZ, Sosic-Jurje vic BT, Filipovic BR, Trifunovic SL, Milosevic V: Daidzein effects on ACTH cells: immunohistomorphometric and hormonal study in an animal model of the andropause. Histol Histopathol 2011, 26:1257-1264. 15. Ajdzanovic VZ, Sosic-Jurje vic BT, Filipovic BR, Trifunovic SL, Brkic DD

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Biochanin a and Daidzein Influence Meiotic Maturation of Pig Oocytes in a Different Manner

in reproductive processes of mammals and birds. Reproductive Biology, 6, 151-174. Fuente R, Eppig J (2001): Transcriptional activity of the mouse oocyte genome: companion granulosa cells modulate transcription and chromatinremodeling. DevelopmentalBiology, 229, 224-236.doi: 10.1006/dbio.2000.9947. Galeati G, Vallorani C, Bucci D, Bernardini C, Tamanini C, Parmeggiani A, Spinaci M (2010): Daidzein does affect progesterone secretion by pig cumulus cells but it does not impair oocytes IVM. Theriogenology, 74, 451-457.doi: 10.1016/j

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Effects of isoflavones on testicular weight and testosterone secretion in ISA Brown roosters

). Luteotrophic action of prolactin during the early luteal phase in pigs: the involvement of protein kinases and phosphatases. Reprod. Biol., 1: 63-83. Ciereszko R., Opałka M., Kami ńska B., G órska T., Dusza L. (2003). Prolactin signaling in porcine theca cells: the involvement of protein kinases and phosphatases. Reprod. Fert. Develop., 15: 27-35. Greiner L.L., Stahly T.S., Stabel T.J. (2001 a). The effect of dietary soy daidzein on pig growth and viral replication during a viral challenge. J. Anim. Sci., 79: 3113-3119. Greiner

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Influence of dietary soy isoflavones on immature hamster uterotrophic and Hershberger assays

of a robust yeast estrogen bioassay for the screening of estrogenic activity in animal feed. Food Addit Contam 2006, 23, 556-568. 6. Brown N.M., Setchell K.D.R.: Animal models impacted by phytoestrogens in commercial chow: implications for pathways influenced by hormones. Lab Invest 2001, 81, 735-747. 7. Casanova M., You L., Gaido K.W., Archibeque-Engle S., Janszen D.B., Heck H.d’A.: Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors α and β

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Augmentation of major isoflavones in Glycine max L. through the elicitor-mediated approach

Abstract

- Isoflavone content in soybean seeds was enhanced by the elicitor-mediated approach under field conditions through the floral application of abiotic elicitors-salicylic acid, methyl jasmonate and biotic elicitors-Aspergillus niger and Rhizopus oligosporus. Among isoflavones, daidzein and glycitein were found to be highly responsive to elicitors, with an increase of 53.7% and 78.7%, respectively as compared to control. Highest total isoflavone content (1276.4 mg g-1 of seeds) was observed upon the administration of 0.1 mMsalicylic acid, which is 92.7% higher than in control. This study would be valuable for augmentation of the isoflavone content in soybean seeds in field grown plants for better nutraceutical potential.

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Foliar Application of Sodium Molybdate Enhanced Nitrogen Uptake and Translocation in Soybean Plants by Improving Nodulation Process Under Salt Stress

Abstract

Soil salinity with different harmful effects on plant growth and productivity is one of the main reasons in diminishing biological nitrogen fixation and nitrogen assimilation in legume plants. Molybdate has a key role on nitrogen metabolism of plants and can be has a beneficial effect on it. Thus, this experiment was conducted to evaluate the effects of sodium molybdate spraying (0.2 and 0.4% solutions in water) on nodulation, nitrogen uptake and translocation in soybean plants under different levels of salt stress (0, 5 and 10 dS m−1 NaCl, respectively). Salinity reduced the nodulation, root and shoot growth and special flavonoids content in roots, which are have a key role in nodulation includes, daidzein, genistein, coumestrol and glycitein, also diminished nitrogenase, glutamine synthetase (GS), glutamate dehydrogenase (GDH), glutamine oxoglutarate aminotransferase (GOGAT) and nitrate reductase (NR) activities in nodes, nitrogen content of nodes, roots and leaves, nitrogen uptake and translocation by soybean plants. Under salt stress and nonsaline condition, sodium molybdate treatments improved the nodulation by increasing flavonoids content of roots, also these treatments enhanced the plant growth and nitrogenase, GS, GDH, GOGAT and NR activities of nodes. Furthermore, nitrogen content of nodes, roots and leaves, nitrogen uptake and translocation by soybean plants improved by sodium molybdate applications. Both of the sodium molybdate doses, exposed the similar effects on improving nodulation and nitrogen metabolism of soybean.

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Bioactive Phenolic Compounds of Soybean (Glycine max cv. Merit): Modifications by Different Microbiological Fermentations

In this work, the effect of solid-substrate fermentation with Aspergillus oryzae, Rhizopus oryzae and Bacillus subtilis of soybean seeds on bioactive phenolic compounds was studied. Among the analysed sample extracts several phenolic compounds, hydroxybenzoics, hydroxycinnamics and fl avonoids, such as fl avonols, fl avanones, isofl avones were identifi ed by HPLC-DAD-ESI/MS. The results obtained indicate that fermentation process carried out in seeds inoculated with different microorganisms produced signifi cant changes in fl avonoids and phenolic acids contents. A signifi cant increase in the content of phenolic acids was observed in the samples fermented with the different microorganisms with respect to soybean without fermentation and fermented naturally. Fermentation process produced also important changes in fl avonoids compounds, with a signifi cant formation in isofl avone aglycone contents such as daidzein, glycitein and genistein as a consequence of glucosidase activity of microorganism in this process, showing signifi cant differences (p<0.05) with respect to control. Therefore, this process was shown to be a good way to increase the phenolic content of soybean, which could confer health-promoting effects.

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The effects of selected flavonoids on cytochromes P450 in rat liver and small intestine

References Atkinson C, Frankenfeld CL and Lampe JW. (2005). Gut bacterial metabolism of the soy isoflavone daidzein: exploring the relevance to human health. Exp Biol Med (Maywood)   230 : 155-170. Burke MD and Mayer RT. (1974). Ethoxyresorufin: direct fluorimetric assay of a microsomal O -dealkylation which is preferentially inducible by 3-methylcholanthrene. Drug Metab Dispos   2 : 583-588. Canivenc-Lavier MC, Vernevaut MF, Totis M, Siess MH, Magdalou J and Suschetet M. (1996

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