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CADUCEUS (CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dysfunction) trial in 2012 was an investigation to determine efficacy of treating myocardial infarction with cardiosphere-derived stem cells (CDCs) in patients vs. standard care. The results suggested that CDCs were a safe and effective treatment option, and played a role in increasing viable myocardial tissue, possibly through paracrine signalling. Although improvement of heart health via significant loss of scarred tissue was reported, there was no notable increase in left ventricular ejection
knowledge base, decision-making processor, data and time driver, data review alerts, accounting system, longitudinal patient data repository, and other components. 6.1.2 The QMR system QMR is a typical CDSS to help physicians, using the knowledge base of INTERNIST-1/CADUCEUS. This knowledge base is widely used as a medical book, which contains 750 diseases, 5,000 clinical symptoms, and more than 50,000 disease relationships. QMR was one of the earliest CDSSs to use artificial intelligence and probability ranking system. Because many of the diseases in the system are rare