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Flozins, inhibitors of type 2 renal sodium-glucose co-transporter – not only antihyperglycemic drugs

References 1. Bhatia K. et al.: Canagliflozin-current status in the treatment of type 2 diabetes mellitus with focus on clinical trial data. World J. Diabetes, 5, 399, 2014. 2. Chao E., Henry R.: SGLT2 inhibition - a novel strategy for diabetes treatment. Nature Rev. Drug Discov., 9, 551, 2010. 3. Diamant M., Morsink L.: SGLT2 inhibitors for diabetes: turning symptoms into therapy. Lancet, 382, 917, 2013. 4. Endocrine Today.

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The blood resistin level in patients with DM2, depending on the duration of the disease

; 409: 307-12. 17. Tokuyama Y. et al.: Serum resistin level is associated with insulin sensitivity in Japanese patients with type 2 diabetes mellitus. Metabolism, 2007; 56 (5): 693-698. 18. Vozarova De Courten B. et al.: High serum resistin is associated with an increase in adiposity but not worsening of insulin resistance in Pima Indian. Diabetes, 2004; 53 (9): 1279-1284.

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Genetic polymorphisms in diabetes: Influence on therapy with oral antidiabetics

Pro12Ala variant in the PPAR-γ2 gene and the response rate to therapy with pioglitazone in patients with type 2 diabetes, Diabetes Care   26 (2003) 825-831; DOI: 10.2337/diacare.26.3.825. K. H. Zhang, Q. Huang, X. P. Dai, J. Y. Yin, W. Zhang, G. Zhou, H. H. Zhou and Z. Q. Liu, Effects of the peroxisome proliferator activated receptor-γ coactivator-1α (PGC-1α) Thr394Thr and Gly482Ser polymorphisms on rosiglitazone response in Chinese patients with type 2 diabetes mellitus, J. Clin. Pharmacol.   50 (2010) 1022-1030; DOI: 10

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Spirulina maxima and its effect on antioxidant activity in fructose induced oxidative stress with histopathological observations

References [1] Aebi H. Catalase in vitro. In: Colowick S.P., Kalpan, N.O (Eds), Methods in Enzymology, Academic press, 1984, 121-126. [2] American Diabetes Association. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, Volume 36, Supplement 1, January 2013, S67-S74. [3] Arulselvan P, Subramanian SP. Beneficial effects of Murraya Koenigii leaves on antioxidant defense system and ultra structural changes of pancreatic β-cells in experimental diabetes in rats. Chem Biol Interact. 2007, 165: 155

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Sildenafil alters biogenic amines and increases oxidative damage in brain regions of insulin-hypoglycemic rats

REFERENCES 1. A. V. Raveendran, E. C. Chacko and J. M. Pappachan, Non-pharmacological treatment options in the management of diabetes mellitus, Eur. Endocrinol. 14 (2018) 31–39; 2. A. Hussain, O. B. Latiwesh, F. Ali, M. Y. G. Younis and J. A. Alammari, Effects of body mass index, glycemic control, and hypoglycemic drugs on serum uric acid levels in type 2 diabetic patients, Cureus 10 (2018) e3158; 3. G. T. Chen, B. B. Yang, J. H. Chen, Z. Zhang, L. L. Zhu, H

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Qualitative and quantitative HPLC-ELSD-ESI-MS analysis of steroidal saponins in fenugreek seed

Trigonella foenum–graecum and its herbal formulations, J. Planar. Chromatogr. – Mod. TLC 28 (2015) 458–465; 23. F. R. Lu, L. Shen, Y. Qin and L. Gao, Clinical observation of Trigonella foenum-graecum saponin combining sulphanylureas on 36 cases of type 2 diabetes mellitus, Chin. J. Integr. Med. 33 (2008) 184–187; 24. T. Kawabata, M.-Y. Cui, T. Hasegawa, F. Takano and T. Ohta, Anti-inflammatory and anti-melanogenic steroidal saponin glycosides from fenugreek

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Relationship between clinical effectiveness and pharmacoeconomic cost in patients with diabetes mellitus

outcomes, costs and cost effectiveness of interventions in diabetes mellitus (types 1 and types 2) to support clinical and reimbursement decision-making, Curr Med Res Opin 2004, 20 (Suppl1):S5-S26 UK PROSPECTIVE DIABETES STUDY (UKPDS) GROUP. Intensive blood-glucose control with sulfonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33), Lancet 1998, 352, p. 837-853. DRUMMOND M. F. - O BRIEN B. - STODDART G. L, - TORRANCE G. W.: Methods for the

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Antioxidative Activity and Inhibition of Key Enzymes Linked to Type-2 Diabetes (α-Glucosidase and α-Amylase) by Khaya Senegalensis

References 1. International Diabetes Federation: Diabetes Atlas 2011, 5th ed., International Diabetes Federation, Brussels 2011. 2. K. Srinivasan, B. Viswanad, A. Lydia, C. L. Kaul and P. Ramarao, Combination of high-fat diet-fed and low-dose streptozotocin treated rat: A model for type 2 diabetes and pharmacological screening, Pharmacol. Res. 52 (2005) 313-320; DOI: 10.1016/j.phrs.2005.05.004. 3. D. Quilliot, E. Walter, J. P. Bonte, J. C. Fruchart, P. Duriez and O. Ziegler, Diabetes mellitus worsens antioxidant

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Carvedilol and Pycnogenol® improve the function of diabetic hearts in rats

muscle in rats with streptozotocin-induced diabetes mellitus. Acta Diabetol. 2010; 47 (1 suppl):153-159. [7] Grimm D, Jabusch H, Kossmehl P, Huber M, Fredersdorf S, Griese DP, Kramer BK, Kromer EP: Experimental diabetes and left ventricular hypertrophy. Effects of beta-receptor blockade. Cardiovas Pathology.2002;11: 229-237. [8] Goyal BR, Parmar K, Goyal RK, Mehta AA: Beneficial role of telmisartan on cardiovascularcomplications associated with STZ-induced type 2 diabetes in rats. Pharmacol Report. 2011; 63: 956-966. [9

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Potential prophylactic role of aminoguanidine in diabetic retinopathy and nephropathy in experimental animals

. Jiang, J. E. Saavedra, L. K. Keefer, J. A. Hrabie and M. R. Kibbe, Heightened efficacy of nitric oxide-based therapies in type II diabetes mellitus and metabolic syndrome, Am. J. Physiol. Heart. Circ. Physiol.   295 (2008) 2388-2398. G. P. Bautista, L. G. Sanchez, C. U. Cristobal, E. Tapia, V. Soto and C. M. Avila, Chronic inhibition of NOS-2 ameliorates renal injury, as well as COX-2 and TGF-beta 1 over expression in 5/6 neprhectomized rats, Nephrol. Diab. Transpl.   21 (2006) 3074-3081. H. J. Han, J. L. Lee, S

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