Search Results

1 - 10 of 387 items :

  • Internal Medicine x
Clear All
Different Tools for the Assessment of Bone Mass among Egyptian Adults

GM, Fogelman I. Role of dual-energy X-ray absorptiometry in the diagnosis and treatment of osteoporosis. J Clin Densitom. 2007; 10:102-110. 5. Bauer JS, Virmani S, Mueller DK. Quantitative CT to assess BMD as a diagnostic tool for osteoporosis and related fractures. Medica Mundi. 2010; 54(2): 31-37. 6. Dargent-Molina P, Piault S, Bréart G. Identification of women at increased risk of osteoporosis: no need to use different screening tools at different ages. Maturitas. 2006;54(1):55-64. 7. Hiernaux J, Tanner JM. Growth and physical studies. In: Human Biology

Open access
Ultrasonographic Evaluation of Maxillofacial Swelling in a Pediatric Patient with Xeroderma Pigmentosum

the Size of Jaw Osseous Lesions. J Dent, 2015;16:335-340. 9. Nawaz MKK. Role of Ultrasound as a Diagnostic Tool in Superficial Facial Space Infections. Int J Scientific Stud. 2015;3:41-47. 10. Feller L, Wood, NH, Motswaledi MH, Khammissa RA, Meyer M, Lemmer J. Xeroderma pigmentosum: a case report and review of the literature. J Prev Med Hyg, 2010;51:87-91. 11. Akdeniz N, Bilgili SG, Çalka Ö, Karadağ AS. Xeroderma pigmentosum in eastern Turkey: a review of 15 cases. Turk J Med Sci, 2012;42:719-723. 12. Mukhi PU, Mahindra UR. The use of

Open access
Nuclear Magnetic Resonance as a Diagnostic Tool in Breast Cancer

Nuclear Magnetic Resonance as a Diagnostic Tool in Breast Cancer

The early detection and treatment of breast cancer is of direct benefit to patients. Magnetic resonance imaging (MRI) is a promising modality for detection, diagnosis, and staging of breast cancer. MRI enables two methods: the diffusion-weighted MRI (DW MRI) and the dynamic contrast enhanced MRI (DCE MRI). DW MRI reflects the diffusion of water molecules in the extracellular fluid space and allows the estimation of cellularity and tissue structure. The value of the diffusion of water in tissue is called the apparent diffusion coefficient (ADC). ADC values in malignant lesions are smaller than in benign tissue. DCE MRI yields appropriate pharmacokinetic data of physiological parameters that relate to tissue perfusion, microvascular vessel wall permeability and extracellular volume fraction. Gadolinium based contrast agent is usually used in breast DCE MRI diagnostics. Changes in the post-contrast signal intensity help to distinguish lesions according to characteristically enhanced accumulation of contrast agent. Malignant lesions are characterized by a faster and stronger signal enhancement than benign lesions which relate to their neoangiogenesis. Over the last few years, there has been appreciable interest in the use of magnetic resonance spectroscopy (MRS) for the non-invasive analysis of breast tisue metabolites. One of the spectroscopic hallmarks of the neoplastic process appears to be the presence of total choline signal in the in vivo spectrum. Despite the fact that MRI and MRS achieve excellent results, they are still not so frequently used in comparison to mammography and breast ultrasound.

Open access
Salivary Theranostics in Pediatric and Special Care Dentistry

emerging biofluid for clinical diagnosis and applications of MEMS/NEMS in salivary diagnostics. In book: Nanobiomaterials in Clinical Dentistry (1st ed., Chapter 22), Elsevier Inc., 2013. 28. Javaid MA, Ahmed AS, Durand R, Simon D. Saliva as a diagnostic tool for oral and systemic diseases. J Oral Biol Craniofac Res, 2016;6:66-75. 29. Gashti MP, Asselin J, Barbeau J, Boudreauab D, Greener J. A microfluidic platform with pH imaging for chemical and hydrodynamic stimulation of intact oral biofilms. Lab Chip, 2016;16:1412-1419. 30. Kaczor-Urbanowicz KE

Open access
Dermoscopy as a Valuable Tool in Diagnosis of Nodular Amelanotic Melanoma and Nodular Basal Cell Carcinoma

Abstract

Nodular amelanotic melanoma has been always a great challenge in dermatology. Because of lack of melanin pigment, tumors are diagnosed usually in advanced stage. Amelanotic melanoma can mimic basal cell carcinoma. Knowledge of typical dermoscopic structures helps to establish diagnosis and to plan surgery with appropriate safety margins. In amelanotic melanoma we can see typical vessels, white streaks or milky red globules on pink-reddish background. Vessels are typically thin and polymorphous in thick amelanotic melanoma. We had a case when vessels were polymorphous but thick. It can be confusing with nodular basal cell carcinoma where vessels are typically thick and arborizing. Nodular basal cell carcinoma is the most common form of basal cell carcinoma. Dermoscopy is a valuable tool for the diagnosis of basal cell carcinoma. Typical dermoscopic structures are arborizing vessels, possible sites of ulceration and/or pigmentation. We describe a case report of patient with typical dermoscopic structures seen in nodular basal cell carcinoma.

Open access
Dose-volume derived nomogram as a reliable predictor of radiotherapy-induced hypothyroidism in head and neck cancer patients

guideline to avoid HT. 12 In the paper from Xu, the threshold level of V50 was set to 54.5%. 20 When all these results are analysed collectively, it can be concluded that the rate of HT is small in patients receiving < 50 Gy. In this study, it was shown that by employing our novel scoring system (HRS) it is possible to additionally stratify a cohort of patients with V50 > 60%, in order to predict the risk of HT development more precisely. Thus, this dose-volume derived nomogram could be a valuable tool in addition to the presently used parameters in everyday clinical

Open access
A comparison of the quality assurance of four dosimetric tools for intensity modulated radiation therapy

Abstract

Background. This study was designed to compare the quality assurance (QA) results of four dosimetric tools used for intensity modulated radiation therapy (IMRT) and to suggest universal criteria for the passing rate in QA, irrespective of the dosimetric tool used.

Materials and methods. Thirty fields of IMRT plans from five patients were selected, followed by irradiation onto radiochromic film, a diode array (Mapcheck), an ion chamber array (MatriXX) and an electronic portal imaging device (EPID) for patient-specific QA. The measured doses from the four dosimetric tools were compared with the dose calculated by the treatment planning system. The passing rates of the four dosimetric tools were calculated using the gamma index method, using as criteria a dose difference of 3% and a distance-to-agreement of 3 mm.

Results. The QA results based on Mapcheck, MatriXX and EPID showed good agreement, with average passing rates of 99.61%, 99.04% and 99.29%, respectively. However, the average passing rate based on film measurement was significantly lower, 95.88%. The average uncertainty (1 standard deviation) of passing rates for 6 intensity modulated fields was around 0.31 for film measurement, larger than those of the other three dosimetric tools.

Conclusions. QA results and consistencies depend on the choice of dosimetric tool. Universal passing rates should depend on the normalization or inter-comparisons of dosimetric tools if more than one dosimetric tool is used for patient specific QA.

Open access
Comment on “State of the art in magnetic resonance imaging of hepatocellular carcinoma”: the role of DWI

extracted by DWI to characterize HCC, data not assessed by authors. 001 DWI has been applied to liver imaging as an excellent tool for detection and characterization of focal liver lesions. The assessment of DW images can be done qualitatively and quantitatively, through the apparent diffusion coefficient (ADC) map. Le Bihan et al . as a first described the intravoxel incoherent motion (IVIM). IVIM data can be assessed qualitatively and quantitatively. IVIM data enable improved detection and characterization of HCC. 2 Also, traditionally DWI approach to analyze data is

Open access
Primary prevention strategy for cardiovascular disease in Lithuania
(“A Funding Programme for the Screening and Preventive Management of the High Cardiovascular Risk Individuals” – main results: 2006–2017 years)

. [The effectiveness of individual aerobic training in subjects with metabolic syndrome]. Daktaro disertacija. Moksl. vadovas prof. A. Juocevičius, moksl. konsultantė dr. L. Ryliškytė. – Vlnius, 2018, 200 p. [34] Matheny M, McPheeters ML, Glasser A, Mercaldo N, Weaver RB, Jerome RN, et al. Systematic Review of Cardiovascular Disease Risk Assessment Tools. Evidence Syntheses/Technology Assessments, No. 85. 2011, 394 p. [35] Grundy SM. Metabolic Syndrome Pandemic. Arterioscler Thromb Vasc Biol 2008; 28(4):629–36. [36] Koller MT, Steyerberg EW, Wolbers M

Open access