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Transient bioimpedance monitoring of mechanotransduction in artificial tissue during indentation

]. However, a more common method, the patch-clamp technique [ 13 , 16 ], uses a pipette or microfabricated aperture into which a small section of the cell membrane (the ‘patch’) is drawn by way of an applied suction. The pipette is filled with an ionic solution and contains a single electrode to record currents through either individual ion channels or over the entire cell membrane. The whole-cell patch-clamp technique [ 16 ] requires a larger suction to be applied so that the membrane is ruptured. This ensures better access to the electrical properties inside the cell

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