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Seyede Zahra Banihosseini, Marefat Ghaffari Novin, Hamid Nazarian, Abbas Piryaei, Siavash Parvardeh and Fatemeh Eini

: 206. Boots A.W., Haenen G.R.M.M., Bast A. (2008). Health effects of quercetin: From antioxidant to nutraceutical. Eur. J. Pharmacol., 585: 325-337. Camargo C.A.,da Silva M.E.F.,da Silva R.A., Justo G.Z., Gomes- Marcondes M.C., Aoyama H. (2011). Inhibition of tumor growth by quercetin with increase of survival and prevention of cachexia in Walker 256 tumor-bearing rats. Biochem. Biophys. Res. Commun., 406: 638-642. Cho J.Y., Kim I.S., Jang Y.H., Kim A.R., Lee S.R., (2006). Protective effect of quercetin, a natural

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Małgorzata Gbylik-Sikorska, Anna Gajda, Artur Burmańczuk, Tomasz Grabowski and Andrzej Posyniak

References 1. de Boer V.C., Dihal A.A., van der Woude H., Arts I.C., Wolffram S., Alink G.M., Rietjens I.M., Keijer J., Hollman P.C.: Tissue distribution of quercetin in rats and pigs. J Nutrit 2005, 135, 1718–1725. 2. Chang L., Ren Y., Cao L., Sun Y., Sun Q., Sheng N., Yuan L., Zhi X., Zhang L.: Simultaneous determination and pharmacokinetic study of six flavonoids from Fructus Sophorae extract in rat plasma by LC–MS/MS. J Chrom B 2012, 904, 59–64. 3. Coppin J.P., Xua Y., Chena H., Pan M.H., Hoc Ch.T., Juliani R., Simon J.E., Wu Q

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Katarzyna Ognik, Ewelina Cholewińska and Anna Czech

lucerne protein concentrate. J. Anim. Feed Sci., 23: 236-243. Hager- Theodorides A.L., Goliomytis M., Delis S., Dligeorgis S. (2014). Effects of dietary supplementation with quercetin on broiler immunological characteristics. Anim. Feed Sci. Tech., 198: 224-230. Jaccob A.A., Hussain S.A. (2012). Effects of long-term use of flavonoids on the absorption and tissue distribution of orally administered doses of trace elements in rats. Pharmacology & Pharmacy, 3: 474-480. Jankowski J., Juśkiewicz J., Zduńczyk P., Kosmala M

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Radaković Milena, Đelić Ninoslav, Stevanović Jevrosima, Anđelković Marko, Kolarević Stoimir, Dačić Stefan and Stanimirović Zoran

oxidative stress caused by dopamine itself. Acta Med Okayama 2008, 62:141-150. 33. Manini P, Panzella L, Napolitano A, d’Ischia M: Oxidation chemistry of norepinephrine: partitioning of the O-quinone between competing cyclization and chain breakdown pathways and their roles in melanin formation. Chem Res Toxicol 2007, 20:1549-1555. 34. Sousa RL, Marletta MA: Inhibition of cytochrome P450 activity in rat liver microsomes by the naturally occurring fl avonoid, quercetin. Arch Biochem Biophys 1985, 240: 345-357. 35. Dhalla, SN

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Milan Ivanov, Nevena Mihailović-Stanojević, Jasmina Marković-Lipkovski, Đurđica Jovović, Danijela Karanović, Zoran Miloradović and Jelica Grujić-Milanović

of oxidative stress in the pathogenesis of vascular calcification in chronic kidney disease. J Bone Miner Res 2012, 27(2):474-85. 23. Paller MS, Hoidal JR, Ferris TF: Oxygen free radicals in ischemic acute renal failure in the rat. J Clin Invest 1984, 74(4):1156-64. 24. Inal M, Altinisik M, Bilgin MD: The effect of quercetin on renal ischemia and reperfusion injury in the rat. Cell Biochem Funct 2002, 20(4):291-6. 25. Jerkic M, Miloradovic Z, Jovovic D, Mihailovic-Stanojevic N, Elena JV, Nastic-Miric D, Grujic-Adanja G, Rodriguez-Barbero A

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Hidayet Tutun, Özlem Özmen, İbrahim Aktaş, Alper Yalçin and Ahmet Türk

doxorubicin. Toxicol Mech Method 2010, 20:298-305. 13. Divya S, Madhuri D, Lakshman M, Reddy AG: Pathological and ultra-structural changes in testis of rats due to doxorubicin toxicity and its amelioration with quercetin. Int. J. Curr. Microbiol. App. Sci 2017, 6:2295-2306. 14. Vapa I, Torres VM, Djordjevic A, Vasovic V, Srdjenovic B, Simic VD, Popović JK: Effect of fullerenol C 60 (OH) 24 on lipid peroxidation of kidneys, testes and lungs in rats treated with doxorubicine. Eur J Drug Metab Pharmacokinet 2012, 37:301-307. 15. Bilir EK, Tutun H, Sevin S

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Iwona Skrzecz, Alicja Sowińska and Wojciech Janiszewski


The aim of the study was to evaluate the possibility of using botanic antifeedants to reduce the damage caused by Melolontha spp. grubs. To achieve the objective, the experiments were established in semi-field conditions to estimate the antifeedant activity of rutin, quercetin (flavonoids from buckwheat Fagopyrum esculentum) and an extract from black alder Alnus glutinosa leaves against Melolontha melolontha grubs. The grubs were placed individually in the pots with a soil in which 2 year old Pinus sylvestris trees were planted. The pots were put in garden pavilions placed in the open area. Then the soil in the pots were watered with the emulsions of rutin, quercetin, an extract from A. glutinosa leaves, and with pure water-comparative variant. After 4 months, the weight and mortality of grubs were compared, as well as the weight of tree roots in all pots.

There was no effect of the antifeedants on the development and extent of damage caused by M. melolontha grubs. The results do not indicate the use of botanic antifeedants in the protection of forests against the cockchafer grubs

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S. Lewicki, W. Stankiewicz, E. Skopińska-Różewska, J. Wilczak, M. Leśniak, M. Suska, A.K. Siwicki, P. Skopiński and R. Zdanowski

MO, Lobo MD, Grangeiro TB, Nobre Junior HV ( 2014 ) Synergistic effect of the flavonoid catechin, quercetin, or epigallocatechin gallate with fluconazole induces apoptosis in Candida tropicalis resistant to fluconazole. Antimicrob Agents Chemother 58: 1468-1478. Dong W, Wei X, Zhang F, Hao J, Huang F, Zhang C, Liang W ( 2014 ) A dual character of flavonoids in influenza A virus replication and spread through modulating cell-autonomous immunity by MAPK signaling pathways. Sci Rep 4: 7237. Erlund I, Alfthan G, Siren H, Ariniemi K, Aro A ( 1999

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Lingyun Y. Wei, Peixin X. Jiao, Trevor W. Alexander and Wen Zhu Yang

considerations. Br. J. Nutr., 83: 143-150. Goering H.K., Van Soest P.J. (1970). Forage fiber analysis (apparatus, reagents, procedures and some applications). Agric. Handbook No. 379. Washington, DC, USA, ARS-USDA, pp. 13-14. Gohlke A., Ingelmann C.J., Nürnberg G., Weitzel J.M., Hammon H.M., Görs S., Starke 1 A., Wolffram S., Metges C.C. (2013). Influence of 4-week intraduodenal supplementation of quercetin on performance, glucose metabolism, and m RNA abundance of genes related to glucose metabolism and antioxidative status in dairy cows. J

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Eva Tvrdá, Michal Ďuračka, Marek Halenár and Attila Kántor

References AGARWAL, J., SRIVASTAVA, S., SINGH, M.: Pathogenomics of uropathogenic Escherichia coli. Indian Journal of Medical Microbiology, 30:141-149, 2012. AHERNE, SA., O’BRIEN, NM.: Mechanism of protection by the flavonoids, quercetin and rutin, against tertbutylhydroperoxide- and menadione-induced DNA single strand breaks in Caco-2 cells. Free Radical Biology and Medicine, 29:507-514, 2000. ALARCÓN DE LA RASTRA C.: Curcumin: a promising spice for therapeutics. Molecular Nutrition & Food Research, 52