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News in Pathogenesis of Chronic Venous Insufficiency

. External supports and the prevention of neointima formation in vein grafts. Eur J Vasc Endovasc Surg 2002; 24(1): 13-22. 33. Kleinedler JJ, Foley JD, Orchard EA et al. Novel nanocomposite stent coating releasing resveratrol and quercetin reduces neointimal hyperplasia and promotes re-endothelialization. J Control Release 2012; 159(1): 27-33. 34. Danenberg HD, Welt FG, Walker M et al. Systemic inflammation induced by lipopolysaccharide increases neointimal formation after balloon and stent injury in rabbits. Circulation 2002; 105(24): 2917-22. 35. Desai

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Original paper: A new type of polyphenols-containing dietary supplement for correction of lipids and inflammatory markers in patients with coronary artery disease

, Smoliga JM, Blanchard O. Enhancing the delivery of resveratrol in humans: if low bioavailability is the problem, what is the solution? Molecules 2014;19:17154-72. [8] D’Andrea G. Quercetin: A flavonol with multifaceted therapeutic applications? Fitoterapia 2015;106:256-71. [9] Lee KH, Park E, Lee HJ, Kim MO, Cha YJ, Kim J, et al. Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers. Nutr Res Pract 2011;5:28-33. [10] Edwards RL, Lyon T, Litwin SE, Rabovsky A, Symons JD, Jalili T

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LncRNA: An all-rounder in rheumatoid arthritis

-regulation of MALAT1 is seen in various human cancers and has been proven to be associated with cancer metastasis and recurrence. [ 55 ] Pan et al . observed theelevation of apoptotic rate of RA FLSs after the treatment of quercetin. [ 56 ] To figure out the molecular mechanism of the effect of quercetin on RA FLSs, alterations of expression of lncRNAs within the cells were analyzed with the application of PCR array and qPCR. And MALAT1 was found to be the most prominently altered lncRNA in RA FLSs. The knockdown of MALAT1 inhibited the apoptosis of the RA FLSs, decreased

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