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Dorota Talarska, Michał Michalak and Patrycja Talarska

REFERENCES Aggarwal A., Datta V., Thakur L.C.: Quality of Life in children with epilepsy . Indian J. Pediatr., 2011, 17: 893–896. Aldenkamp A.P., Van Donselaar C.A., Flamman A., Lafarre D.L.W.: Psychological reactions to the epilepsy in an unselected group of patients with epilepsy under treatment in general hospitals . Seizure, 2003, 12: 101–106. Amiri P., Eslamian G., Mirmiran P., Shiva N., Jafarabadi M.A., Azizi F.: Validity and reliability of the Iranian version of the Pediatric Quality of Life Inventory ™ 4.0 (PedsQL ™ ) Generic Core

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Dobromir D. Dimitrov, Tsvetomir M. Ivanov, Tashko S. Deliyski, Sergey D. Iliev, Emil T. Filipov, Martin P. Karamanliev, Tatqna M. Betova, Savelina L. Popovska, Nataliya P. Chilingirova, Izabela P. Georgieva, Slavcho T. Tomov and Grigor A. Gortchev

, Weir R, Calcetera N, Quirke P, Carmack S. Pathologic processing of the total mesorectal excision. Clin Colon Rectal Surg. 2015;28(01):43-52. 10. Langer D, Tučková I, Kalvach J, Ryska M. Can robotic rectal cancer surgery improve quality of total mesorectal excision? Rozhl Chir. 2017;96(2):69.

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Țica Ovidiu, Otilia Anca Țica, Adrian Hatos, Larisa Roșan and Mircea Ioachim Popescu

Cardiology (ESC). Europace 2010;12:1360-420 6. Peinado R, Arribas F, Ormaetxe JM, Badia X. Variation in quality of life with type of atrial fibrillation. Rev Esp Cardiol 2010;63:1402- 1409 7. Steg PG, Alam S, Chiang CE, Gamra H, Goethals M, Inoue H, et al. RealiseAF investigators. Symptoms, functional statusand quality of life in patients with controlled and uncontrolled atrial fibrillation: data from the RealiseAF cross-sectional international registry. Heart 2012;98:195-201 8. Nikolaidou T, Channer KS. Chronic atrial

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José Pimentel

REFERENCES Baker G.A., Jacoby A., Buck D., Stalgis C., Monnet D.: Quality of life of people with epilepsy: a European study . Epilepsia, 1997, 38: 353–362. Klein P., Tyrlikova I., Mathews G.C.: Dietary treatment in adults with refractory epilepsy: a review . Neurology, 2014, 83: 1978–1985. Gaitatzis A., Carroll K., Majeed A., Sander J.W.: The epidemiology of the comorbidity of epilepsy in the general population . Epilepsia, 2004, 45: 1613–1622. World Health Organization (WHO): Disease Burden: Regional Estimates for 2011 . Available

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Nina P. Ayvazova, Violeta S. Rilcheva, Emiliana I. Konova, Roumen G. Roussev and Pavel I. Rashev

. DNAintegrity in human spermatozoa: relationships with semen quality. J Androl. 2000;21(1):33-44. 22. Lopes S, Sun J G, Jurisicova A, Meriano J, Casper RF. Sperm deoxyribonucleic acid fragmentation is increased in poor-quality semen samples and correlates with failed fertilization in intracytoplasmic sperm injection. Fertil Steril. 1998;69(3):528-32. 23. Sun JG, Jurisicova A, Casper R F. Detection of deoxyribonucleic acid fragmentation in human sperm: correlation with fertilization in vitro. Biol Reprod. 1997;56(3):602-7. 24

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Pencho P. Genov, Nikolay H. Kolev, Rumen P. Kotsev, Vladislav R. Dunev, Boyan A. Stoykov, Aleksander A. Vanov, Jitian A. Atanasov and Pencho T. Tonchev


Premature ejaculation (PE) is the most common sexual dysfunction in men, yet it is not well studied. Its frequency reaches 30% for men from 18 to 59 years of age in different countries. The aim of this article was to investigate the quality of sexual life in men with primary PE operated on with microsurgical penile denervation, using the Brief Male Sexual Functional Inventory (BMSFI). From September 2011 to March 2014, 22 patients were operated on with microsurgical penile denervation in the urology clinic of the University Hospital - Pleven and the Department of Urology at UMHAT Ruse AD. The mean result from the BMSFI in patients was 22 points preoperatively, indicating significant worsening of sexual function and quality of life in all five questionnaire domains. After surgery, the results increased to 28, 33 and 39 respectively, at 3, 6 and 12 months, respectively. Premature ejaculation not only leads to problems in controlling ejaculation but also worsens the overall sexual function and quality of life of patients.

Open access

Rumyana N. Kuzmanova, Irina Z. Stefanova, Irena V. Velcheva and Katerina I. Stambolieva

References 1. Baker GA, Jacoby A, Buck D, Stalgis C, Monet D. Quality of life of people with epilepsy: a European study. Epilepsia. 1997;38(3):353-62. 2. Cramer JA, Brandenburg NA, Xu X, Vera-Llonch M, Oster G. The impact of seizures and adverse effects on global health ratings. Epilepsy Behav. 2007;11(2):179-84. 3. Fisher RS, Vickrey BG, Gibson P, Hermann B, Penovich P, Scherer A et al. The impact of epilepsy from the patient's perspective II: views about therapy and health care. Epilepsy Res. 2000;41(1):53-61. 4. Gilliam F. Optimizing