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Health-related quality of life in Croatian general population and multiple myeloma patients assessed by the EORTC QLQ-C30 and EORTC QLQ-MY20 questionnaires

in physical functioning, role functioning, emotional functioning, cognitive functioning and social functioning according to a place of residence; the scores are again the highest for respondents from Istria and Medimurje. Figure 1 Summary score for EORTC QLQ-C30 in general population, initial testing and post-testing. Table 2 Mean score (MS) and standard deviation (SD) for all EORTC QLQ-C30 dimensions and scales in general population and multiple myeloma (MM) patients at diagnosis at the time of setting the diagnosis MM patients at diagnosis

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Factors affecting the morbidity and mortality of diverting stoma closure: retrospective cohort analysis of twelve-year period

., Chicago, Illinois, USA). Continuous data are expressed as means ± SD, while categorical variables are given as percentages. The Shapiro-Wilk test was used to determine whether the continuous data were normally distributed. Comparisons of continuous variables were carried out with Student’s t-test for parametric data and Mann–Whitney U test for nonparametric data. The Chi-square test was used for comparison of discrete variables. A p-value of <0.05 was considered as statistically significant. Results The medical records of 260 patients with stoma closure at the

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Heterotopic ossification: radiological and pathological review

placebo, but at the expense of medication side effects such as gastrointestinal ulcers, bleeding, and delayed bone healing. 88 , 89 Although there is a decrease in HO formation, NSAIDs had no effect on pain or physical function compared to placebo. 88 , 90 , 91 NSAIDs target pro-inflammatory prostaglandins, which have been shown to be integral to osteogenesis and are thought to have some effect by suppressing the migration and proliferation of mesenchymal cells. 21 , 92 , 93 The NSAID of choice is the non-selective cox inhibitor indomethacin. 94 Cox-2 specific

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BRCA1/2 associated cancer susceptibility: a clinical overview

. This makes access easier for patients who would need to travel a long distance to receive their counselling. The only limitation with distance counselling would be physical findings, such as skin/mucosal lesions, indicative of rare syndromes (such as Cowden’s, Peutz-Jeghers, etc.). Genetic testing Genetic testing is offered to members of families, taking into consideration the probability of a positive result. As an attempt to quantify this probability, various models such as BRCAPRO, BOADICEA, Myriad Tables etc. may be utilised, using medical and family

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Functional And Survival Outcome Of Egyptian Children And Adolescents With Malignant Bone Tumors: An Experience In A Setting Of Limited Health Resource

-75th percentiles). Qualitative variables were described as number and percentage. Kaplan-Meier analysis was used to estimate the overall survival and disease-free rates. Log-rank test was used to compare the different prognostic factors. In order to compare two independent groups with quantitative parametric distributed variables, Independent t-test was performed. Pearson correlation coefficients were applied in order to examine the relation between two studied parameters within the same group. The cutoff level for p-value was considered significant if the P value

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25th Hellenic conference of Clinical Oncology

docetaxel/nintedanib combination. Results : Patient complained for mastodynia and physical examination revealed bilateral gynaecomastia without any clinical signs of inflammation. Hormonal tests revealed an elevated serum b-hCG (17 MIU/ml), while a testicular ultrasound was normal. Analgesics were prescribed to alleviate breast pain. Patient succumbed due to NSCLC disease progression. Conclusions : Gynaecomastia is a rare paraneoplastic manifestation of NSCLC caused by ectopic b-hCG production. It may present either bilaterally or unilaterally, often on the tumor

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Long term survival in 200 patients with advanced stage of colorectal carcinoma and diabetes mellitus – a single institution experience

) physical status classification, which accurately predicts morbidity and mortality. 10 Bioelectric impedance analysis (BIA) measurement was performed on the day before the surgery using a portable bioelectrical impedance analyzer BodyStat QuadScan 4000 (Douglas, Great Britain), as already described by Kerin-Povsic et al . 7 Phase angle is the ratio between the reactance and resistance. 11 The illness marker is the ratio between the impedance measurement at 200kHz and 5kHz. A ratio closer to 1.00 indicates poor cellular health or extreme fluid overload. DM was found

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Giant Brunner's gland adenoma as an unusual cause of anaemia: report of a case

Giant Brunner's gland adenoma as an unusual cause of anaemia: report of a case

Background. Brunner's gland adenoma (BGA) is a rare benign duodenal tumour proliferating from Brunner's glands. Here, we present a giant BGA leading to anaemia, with its clinical, endoscopic, radiological, surgical and pathological findings.

Case report. A 48-year-old Turkish man complained of a six months history of vague epigastric discomfort, loss of appetite and nausea after meals without vomiting. The physical examination had no unremarkable finding. Laboratory findings, including liver function tests, were within normal limits except a hypochromic, microcytic anaemia. The upper gastrointestinal endoscopic examination revealed a lobulated, red, polypoid tumour with a smooth surface covered with normal mucosa. The tumour was located on the anterior surface of duodenal bulb and had a wide base measuring 3.5 × 4 cm in size. Endoscopic ultrasonography revealed a submucosal polypoid mass located at the anterior surface of duodenal bulb. The endoscopic excision was tried but was not successful. The patient was operated and transduodenal polypectomy was done. The postoperative period was uneventful and the pathologic diagnosis was assessed as Brunner's gland adenoma. During the follow-up period, the endoscopic examination was normal at 12th month postoperatively.

Conclusions. BGA is a rare benign cause of anaemia that can be treated with excellent results.

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Carotid artery stiffness, digital endothelial function, and coronary calcium in patients with essential thrombocytosis, free of overt atherosclerotic disease

617F positive myeloproliferative disease. Our aim was to test whether patients with JAK2 V617F positive MPNs, without clinically manifest atherosclerosis, have more prevalent asymptomatic carotid plaques, greater carotid artery stiffness, greater coronary calcium burden and worse digital endothelial function than apparently healthy control subjects, matched for classical risk factors for atherosclerosis. Patients and methods Patients were recruited from University Medical Centre Ljubljana, Department of Haematology among JAK2 V617F positive patients with

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Health-related quality of life assessed by the EORTC QLQ-C30 questionnaire in the general slovenian population

much with age. TABLE 2 Mean scores (MS) with standard deviations (SD) for all scales and items by gender Total Men Women p (t-test) MS SD MS SD MS SD Global health status/quality of life 71.1 21.4 72.5 21.4 69.7 21.3 0.882 Physical functioning 91.8 14.0 93.3 12.6 90.3 15.1 <0.000 Role functioning 88.7 20.1 90.0 19.3 87.5 20.9 0.056 Emotional functioning 82.0 18.5 83.6 18.4 80.4 18.5 0.686 Cognitive functioning 90.2 16.0 90.2 16

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