, phosphonomycin amino butyl alcohol three salt granules, and fosfomycin two sodium salt for injection.
Although the clinical application of phosphomycin has increased in recent years, there are few clinical reports in China. According to the related literatures at home and abroad, this review briefly introduces fosfomycin in the following three aspects: progress in synthetic methods, pharmacokinetic and pharmacodynamic characteristics, and antibacterial activities, to provide references for clinical rational use.
The synthesis of fosfomycin
Fosfomycin was first
Zhi-liang Hu, Hong-xia Wei, Wen-hu Yao and Yong-feng Yang
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Professional Staff Committee of Combination Therapy of Chronic Hepatitis B
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, and other factors of the current, local, hospital, department, and use empirical antimicrobial agents early [ 24 ]. Moreover, whether the case is hospital-acquired or out-of-hospital infection should be determined, and the presence of a clear focus of infection should be known. The selected drug should be a wide spectrum of antimicrobial agent that covers possible pathogenic microorganisms (bacterial or fungal) and has good penetration in the likely infected tissue. The pharmacokinetics of the antimicrobials will change significantly during the course of treatment