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Therapeutic Drug Monitoring in Rheumatic Diseases

1 Introduction The main goal of treating rheumatic diseases is to achieve rapid and effective suppression of inflammation. More and more drugs have been proven to be able to achieve these goals nowadays. The current practice is to give a recommended dose of drugs to our patients according to the body weight, risk factors and tolerance, etc. However, all our patients are different individuals who have different pharmacokinetics, and this difference in pharmacokinetics can affect the true drug concentration that is working inside them. This may create

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The effect of glycerol supplements on aerobic and anaerobic performance of athletes and sedentary subjects

-Induced Hyperhydration on Cardiovascular Functions and Endurance Performance in Athletes During the Course of Treadmill Exercise Performed at High Temperatures. World Appl Sci J , 2011; 12: 1114-1124 Robergs RA, Griffin SE. Glycerol Biochemistry, pharmacokinetics and clinical and practical applications. Sports Med, 1998; 3: 145-167 Sawka MN, Montain SJ. Fluid and electrolyte supplementation for exercise heat stress. Am J Clin Nutr , 2000; 72: 564-572 Sawka MN, Montain SJ, Latzka WA. Hydration effects on thermoregulation and performance

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Relationships Between Systolic Time Intervals and Heart Rate During Initial Response to Orthostatic Manoeuvre in Men of Different Age

significance of systolic time intervals in hypertensive patients, Eur Heart J , 1990. 11(Suppl. I):105-13. Harjola VP, Oikarinen L, Toivonen L, Jurkko R, Puttonen J, Sarapohja T, Sundberg S, Nieminen MS. The hemodynamic and pharmacokinetic interactions between chronic use of oral levosimendan and digoxin in patients with NYHA Classes II-III heart failure. Int J Clin Pharmacol Ther. 2008. 46(8):389-99. Jantti PO. Orthostatic reactions in the 85-year old,. Aging , 1992. 4(2):139-44. Johnson RH

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The Role of Adrenomedullin in Cardiovascular Response to Exercise – A Review

-receptor-like receptor Nature 1998 393 333 339 Meeran K, O’Shea D, Upton PD, Small CJ, Ghatei MA, Byfield PH, Bloom SR. Circulating adrenomedullin does not regulate systemic blood pressure but increases plasma prolactin after intravenous infusion in humans: a pharmacokinetic study. J Clin Endocrinol Metab , 1997; 82: 95-100 Meeran K O’Shea D Upton PD Small CJ Ghatei MA Byfield PH Bloom SR Circulating adrenomedullin does not regulate systemic blood pressure but increases plasma prolactin after intravenous infusion in humans: a pharmacokinetic study J Clin Endocrinol Metab 1997 82

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