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Genetic Markers Associated with Power Athlete Status

mineral density and onset of osteoporosis. It might be speculated that this SNP would play a role in regulation of bone mass in humans. Thus, athletes carrying the specific form of the CALCR gene might benefit from having stronger bones that are better adjusted to withstand extreme forces and transfer loads over the normal loading conditions. This aspect is especially important for athletes performing strength sports such as powerlifting or weightlifting, for which tremendous weight loads are transferred throughout the whole training program and during competition

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ANA Testing: What should we know about the methods, indication and interpretation?

1 Introduction Autoantibody detection plays an important role in the clinical management of patients with connective tissue disease. Detection of Anti-nuclear antibody (ANA) is a common screening test ordered during initial workup. Though ANA testing is simple, different laboratories vary in their test methodology and reporting format, and that could be confusing. In this review, a general introduction on the common diagnostic assays employed in ANA test, along with issues related to the interpretation would be discussed. In addition, an update on anti

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The Use of PET-CT in Rheumatology

1 Background and technical aspects of PET-CT Positron emission tomography–computed tomography (PET-CT) is the fusion of functional and anatomic scan that acquired almost simultaneously. It helps us to visualize the form and activity of potential diseases within the body. It is now a popular nuclear imaging modality for the evaluation of cancer, fever or inflammation of unknown origin. The differential diagnosis sometimes includes the rheumatic disorders. It is based on the fact that the glucose transporters are up regulated on cell membrane secondary to

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Can Supplementation of Vitamin D Improve Aerobic Capacity in Well Trained Youth Soccer Players?

Introduction The role of active vitamin D in calcium-phosphorus balance and its influence on the metabolism of bones was known as long as 100 years ago ( Wolf, 2004 ). Proliferative effect of this vitamin was identified only after the discovery of its nuclear receptor - VDR. It occurred that the receptor was present in numerous organs beyond the skeletal system, e.g. in the kidneys, the heart, the brain, the pancreas, the intestines as well as in muscles and skin ( Bikle, 2009 ). It was also confirmed that vitamin D played an important role in immunological

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Does the MTHFR A1298C Polymorphism Modulate the Cardiorespiratory Response to Training?

genotype distribution of the MTHFR A1298C polymorphism in a group of Polish women; furthermore, we measured the changes of VO2max test variables, Wingate test variables and body composition measurements before and after the completion of a 12-week training program to verify whether there was an interaction between the genotype and training. Material and Methods Ethics Statement All the procedures followed in the study were approved by the Ethics Committee of the Regional Medical Chamber in Szczecin (Approval number 09/KB/IV/2011) and were conducted according

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Eye movement abnormalities in essential tremor

differences in statistical power. Since age influences latency and velocity of saccades, the findings described above might have been caused by a higher number of elder subjects. Reflexive saccades latency depends mainly on cortical and subcortical areas of the saccadic system. The velocity of saccades is programmed by the brainstem saccades generator ( Leigh and Zee, 2006 ). We did not find impairment of the gap and overlap effect on reflexive saccades latency in ET. Our results of reflexive saccades latency in the gap paradigm remained in accordance with the results of

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