The aim of the research was to find out the realization of the physical activity among the middle-aged adults by the association with their health, retrospective of the factor contributing to the transfer of the physical activity to the adulthood. The monitored group consisted of 742 respondents of the middle-aged adults from the Southern Districts of Slovakia, of which 403 were the women (age = 37.2 ± 3.04 years) and 339 were the men (age = 36.5 ± 4.54 years) as the selection was deliberate. The monitoring was conducted by the three stages in 2014, through the so-called “Egészség és mozgás” - “Health and Movement” standardized, anonymous questionnaire, which consisted of 60 questions. Our findings point to the stated facts. The findings found the relationship between the health and fitness among the men (r = 0.8300), as well as among the women (r = 0.7193). The relationship between the physical activity and the feeling of health was recorded only among the men (r = 0.8921), while the relationship between the health problems and the feeling of health was also found among the men (r = 0.739), as well as among the women (r = 0, 6714). At the same time, the men perceive the importance of the physical activity, in terms of their health condition (r = 0.8791) more intense than the women. The physical education was significantly (χ2 = 112.47, p < 0.01) among the men (67.6 %, n = 229), opposite to the women (33.7 %; n = 136) contributed to the transfer of the physical activity from the school environment to the adulthood. The stated findings show that the targeted education of the population, even from the childhood with the other effective, preventive measures is very important.