;78(6):987-93. 15. Kawashima M, Rhoton AJ, Tanriover N, Ulm AJ, Yasuda A, Fujii K. Microsurgical anatomy of cerebral revascularization. Part I: anterior circulation. J Neurosurg. 2005;102(1):116-31. 16. Kawashima M, Rhoton AJ, Tanriover N, Ulm AJ, Yasuda A, Fujii K. Microsurgical anatomy of cerebral revascularization. Part II: posterior circulation. J Neurosurg. 2005;102(1):132-47. 17. Funaki T, Matsushima T, Peris-Celda M, Valentine RJ, Joo W, Rhoton AJ. Focal transnasal approach to the upper, middle, and lower clivus. Neurosurgery. 2013
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. Tada T, et al.: Human ductus arteriosus. A histological study on the relation between ductal maturation and gestational age. Acta Pathol Jpn 1985, 35 (1) : 23-34 5. Slomp J, et al.: Formation of intimal cushions in the ductus arteriosus as a model for vascular intimal thickening. An immunohistochemical study of changes in extracellular matrix components. Atherosclerosis 1992, 93 (1-2): 25-39 6. de Reeder EG, et al.: Distribution of prostacyclin synthase, 6-ketoprostaglandin F1 alpha, and 15-hydroxy-prostaglandin dehydrogenase in the
Henu Kumar Verma, Saikrishna Lakkakula and Bhaskar V.K.S. Lakkakula
, HbD, HbE, and HbO. Figure 1 Classification of inherited hemoglobin disorders. The distribution of hemoglobinopathies varies from place to place, and much of the global burden of hemoglobinopathies is mainly correlated with malaria endemicity [ 3 ]. Further, hemoglobin SS disease (SCA) is the most common cause of sickle cell disease (SCD) and is most prevalent in Africa, Asia, and Mediterranean regions [ 4 ]. Beta-thalassemia is prevalent in populations of African descent and in regions of the Mediterranean, the Middle East, Transcaucasus, Central