Search Results

1 - 10 of 57 items :

  • Surgery, other x
Clear All
The role of inflammatory mediators in the pathogenesis of nasal polyposis: Literature review

cells are at the interface of innate and adaptive immunity. Curr Opin Immunol., 2007;19(6):711-720. 10. Di Lorenzo G., Drago A., Esposito Pellitteri M., Candore G., Colombo A., Gervasi F., Pacor M.L., Purello D’Ambrosio F., Caruso C. - Measurement of inflammatory mediators of mast cells and eosinophils in native nasal lavage fluid in nasal polyposis. Int Arch Allergy Immunol., 2001;125(2):164-175. 11. Erbek S.S., Yurtcu E., Erbek S., Atac F.B., Sahin F.I., Cakmak O. - Proinflammatory cytokine single nucleotide polymorphisms in nasal

Open access
Epicardial Fat-mediated Inflammation: a Major Player in Cardiovascular Diseases

, Mitre A, Korodi S, et al. Epicardial Fat, Paracrine-mediated Inflammation and Atrial Fibrillation. Journal of Interdisciplinary Medicine . 2017;2:304-307. 16. Tscharre M, Hauser C, Rohla M, et al. Epicardial adipose tissue and cardiovascular outcome in patients with acute coronary syndrome undergoing percutaneous coronary intervention. Eur Heart J Acute Cardiovasc Care . 2017;6:750-752. 17. Tanindi A, Kocaman S, Erkan A, et al. Epicardial adipose tissue thickness is associated with myocardial infarction and impaired coronary perfusion. Anatol J Cardiol

Open access
Neutropenia and T-Wave Inversion as Toxin-Mediated Complications of a Streptococcal Infection

Abstract

Introduction: Streptococcal infection can be responsible for multiple complications, such as toxic, septic or allergic disorders. Toxin-mediated complications (TMC) can appear during the acute phase of disease and can involve any organ, causing carditis, arthritis, nephritis, hepatitis etc.

Case presentation: The case of a young woman without a history of recurrent streptococcal tonsillitis, admitted to “Matei Balş” National Institute for Infectious Diseases, Bucharest, Romania, presenting with fever, sore throat and exudative tonsillitis, is detailed. The initial test for Streptococcus pyogenes was negative. The patient had leukopenia with severe neutropenia, high values of inflammatory biomarkers and electrocardiographic (ECG) changes with inverted T waves in leads V1-4 and flattened T waves in V5-6. There were no other cardiac signs or symptoms. The patient received cefuroxime for two days. On admission, the patient was prescribed Penicillin G and dexamethasone which resulted in a rapid recovery. The leucocytes count returned to normal as did the ECG abnormalities. At the time of discharge, the antistreptolysin O titre was high.

Conclusions: The case highlights the toxin-mediated complications (TMC) of streptococcal infection which occur from the outset of the disease.

Open access
Epicardial Fat, Paracrine-mediated Inflammation and Atrial Fibrillation

Abstract

Atrial fibrillation is the most frequent arrhythmia in adults, becoming more frequent with age. Recent clinical studies demonstrated that epicardial fat is linked with atrial fibrillation induction and recurrence. The arrhythmogenic mechanism consists in the fact that the epicardial adipose tissue is metabolically active, inducing local inflammation and enhancing the oxidative stress, which lead to atrial fibrillation as well as atherosclerosis. Having metabolic activity and secreting various anti- and pro-inflammatory biomarkers, the fat surrounding the heart has been linked to the complex process of coronary plaque vulnerabilization. This clinical update aims to summarize the role of epicardial adipose tissue in the pathogenesis, persistence, and severity of atrial fibrillation.

Open access
Rotational thromboelastometry (ROTEM) 24 hours post liver transplantation predicts early allograft dysfunction

red blood cells is associated with decreased graft survival after orthotopic liver transplantation. Liver Transpl 2013; 19: 1181-1188. doi: 10.1002/lt.23695 16. Lesurtel M, Raptis DA, Melloul E, Schlegel A, Oberkofler C, El- Badry AM, et al. Low platelet counts after liver transplantation predict early posttransplant survival: the 60-5 criterion. Liver Transpl 2014; 20: 147-155. doi: 10.1002/lt.23759 17. Lisman T, Porte RJ. Mechanisms of platelet-mediated liver regeneration. Blood 2016; 128: 625-629. doi: 10.1182/blood- 2016

Open access
Pupillary dilation reflex and pupillary pain index evaluation during general anaesthesia: a pilot study

Pathol Oral Radiol Endod 2001; 91: 654-658. doi: 10.1067/moe.2001.115465 18. De Jonckheere J, Bonhomme V, Jeanne M, Boselli E, Gruenewald M, Logier R, et al. Physiological Signal Processing for Individualized Anti-nociception Management During General Anesthesia: a Review. Yearb Med Inform 2015; 10: 95-101. doi: 10.15265/IY-2015-004 19. Larson MD, Tayefeh F, Sessler DI, Daniel M, Noorani M. Sympathetic nervous system does not mediate reflex pupillary dilation during desflurane anesthesia. Anesthesiology 1996; 85: 748

Open access
Polcalcins as pollen panallergens in allergic rhinitis

Abstract

Polcalcins are highly cross-reactive calcium-binding allergen components specifically expressed in pollen from trees, grasses and weeds. The grass allergen component rPhl p 7, a recombinant non-glycosylated calcium-binding protein of 2-EF-hand type, is the most cross-reactive polcalcin and may be used as a polcalcin biomarker of IgE-mediated hypersensitivity. Polcalcin sensitization, which appears to be linked to geographical factors, level and time of pollen exposure, has to be assessed in allergic rhinitis patients with multiple pollen sensitizations and may be useful for a better targeted prescription of allergen immunotherapy.

Open access
Generalized Severe Plaque Psoriasis in an HIV Positive Patient – a Challenging Treatment

Abstract

Psoriasis is a systemic chronic immune-mediated disorder, rarely reported in HIV-infected patients, in which the disease is more severe and debilitating. Response to treatment is modest, and skin diseases may profoundly affect the patients’ quality of life. Anti-psoriasis therapies have immunosuppressive effects and must be carefully recommended in HIV-infected patients. Moreover, the compliance of HIV patients diagnosed with psoriasis is low, and monitoring these patients is challenging. Herein we present a rare case of severe HIV-associated psoriasis with large plaques localized on the trunk, abdomen, limbs and plantar area in a non-compliant patient, with impaired renal and hepatic functions, dyslipidemia, and anemia, for whom the therapeutic approach was disappointing.

Open access
Influence of Hypothermia on the Clinical and Molecular Status of a Freshwater Drowning Victim with Severe Trauma. A Case Report

Abstract

Drowning in freshwater kills many people around the world. Complications are multiple and sometimes impossible to treat. Fluid and electrolyte resuscitation is difficult because of all the physiological, biophysical and biochemical changes that decrease the rate of survival. Extreme lung injury and cardiovascular disorders are responsible for tissue hypoxia, increased production of inflammation markers, biosynthesis of reactive oxygen species and finally, multiple organ damage. Hypothermia, frequently associated with drowning, provides multiple benefits to this type of patients. Various studies have developed the idea that hypothermia protects the brain from biochemical mediators, thereby preventing neuronal cell destruction. In this case report we present the biological parameters and evolution of a patient drowned in freshwater, and also the benefits of hypothermia to the clinical picture.

Open access
The cranial nerve zero – mini review

Abstract

The terminal nerve (cranial nerve zero, cranial nerve XIII, the nerve “N”) was discovered in fish in 1894. In the early 90’s, it was found in human embryos and human adults. In the anterior fossa, it courses on the inner side of the olfactory tract and bulb; it then spreads fibers through the cribriform plate to distribute beneath the nasal septum mucosa. Being provided with intrinsic ganglion cells, its functions are weakly suggested by studies in different species. It may be connected with the visual system, it could act upon the intracranial vascular system, or it could ensure the pathway for pheromone-mediated behaviours. The cranial nerve zero deserves a better attention equally from anatomists and ENT specialists.

Open access