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Carmen Dobjanschi and Rucsandra Dănciulescu Miulescu


Women with gestational diabetes mellitus (GDM) have an increased lifetime risk of developing type 2 diabetes mellitus (T2DM). GDM has a substantial impact on maternal and foetal short and long-term health. Risk factors for GDM may be genetic or nongenetic and have been analysed in numerous studies. Researches in recent years allowed the identification of other risk factors for GDM except for those already known. Knowledge and identification of all risk factors for GDM allows the elaboration of a prevention strategy of T2DM, it may influence the screening, diagnosis, and, subsequently, treatment modalities for this disease.

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Marlena Pascu, Ruxandra Miulescu and C. Ionescu-Tîrgoviste

lifetime risk for diabetes in the U. S. Diabetes Care 30: 1562-1566, 2007. Dunstan DW, Zimmet PZ, Welborn TA, De Courten MP, Cameron AJ, Sicree RA, Dwyer T, Colagiuri S, Jolley D, Knuiman M, Atkins R, Shaw JE. The rising prevalence of diabetes and impaired glucose tolerance: the Australian Diabetes Care 25: 829-834, 2002. HAPO Study Cooperative Research Group. Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: Intl J Gynecol Obstet 78: 69-77, 2002. HAPO Study Cooperative Research

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Guo-Jun Yang

References 1. National Cardiovascular Disease Center. Chinese Cardiovascular Disease Report 2008-2009. Beijing: Encyclopedia of China Publishing House; 2010. p. 1. 2. Vasan RS, Beiser A, Seshadri S, Larson MG, Kannel WB, D’Agostino RB, et al. Residual lifetime risk for developing hypertension in middle-aged women and men: The Framingham Heart Study. JAMA 2002;287:1003-10. 3. Junga K, Merlo J, Gullberg B, Bog-Hansen E, Rastam L, Lindblad U. Residual risk for acute stroke in patients with type 2 diabetes and

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Shazia Qasim Jamshed, Akshaya Srikanth Bhagavathula and Abdul Kareem Al-Shami

different regimens of intermediate-and short-acting insulin in childhood type 1 diabetes mellitus: an experience from a tertiary care centre. Int J Diabetes Dev Ctries, 2016. 25. Zhuo X, Zhang P, Barker L, Albright A, Thompson TJ, Gregg E. The lifetime cost of diabetes and its implications for diabetes prevention. Diabetes care 37(9): 2557-2564, 2014. 26. Sheldon B, Russell‐Jones D, Wright J. Insulin analogues: an example of applied medical science. Diabetes Obes Metabol 11(1): 5-19, 2009. 27. King DK, Glasgow RE, Toobert DJ

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Marilena Mitrache, Robert Ancuceanu and Constantin Ionescu-Tîrgoviște

mass index history and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Am J Clin Nutr 84: 427-433, 2006. 15. Narayan KMV, Boyle JP, Thompson TJ, Gregg EW, Willamson DF. Effect of BMI on lifetime risk for diabetes in the U.S. Diabetes Care 30: 1562-1566, 2007. 16. Popescu RM, Graur M, Șerban V. Optimizarea stilului de viață. In: Tratat Român de Boli Metabolice vol. 1. Şerban V (Ed). BrumaR, Timișoara, pp 260, 2010. 17. Ionescu-Tîrgoviște C

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Jianping Li, Shanqun Jiang, Yan Zhang, Genfu Tang, Yu Wang, Guangyun Mao, Zhiping Li, Xiping Xu, Binyan Wang and Yong Huo

: the atherosclerosis risk in communities study, 1987-1997. Arch Intern Med 2002;162:2565-71. 21. Kuller LH, Arnold AM, Psaty BM, Robbins JA, O’Leary DH, Tracy RP, et al . 10-year follow-up of subclinical cardiovascular disease and risk of coronary heart disease in the Cardiovascular Health Study. Arch Intern Med 2006;166:71-8. 22. Seshadri S, Beiser A, Kelly-Hayes M, Kase CS, Au R, Kannel WB, et al . The lifetime risk of stroke: estimates from the Framingham Study. Stroke 2006;37:345-50. 23. Stegmayr B, Asplund K, Kuulasmaa K, Rajakangas AM

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Bulent Ergin, Coert J. Zuurbier, Rick Bezemer, Asli Kandil, Emre Almac, Cihan Demirci and Can Ince

-Weerts JH, Balestra GM, et al. In vivo mitochondrial oxygen tension measured by a delayed fluorescence lifetime technique. Biophys J 2008; 95: 3977-90. 30. Bezemer R, Faber DJ, Almac E, Kalkman J, Legrand M, Heger M, et al. Evaluation of multi-exponential curve fitting analysis of oxygenquenched phosphorescence decay traces for recovering microvascular oxygen tension histograms. Med Biol Eng Comput 2010; 48: 1233-42. 31. Demirci C, Gargili A, Kandil A, Cetinkaya H, Uyaner I, Boynuegri B, et al. Inhibition of inducible nitric oxide synthase

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Vania Cruz-Ramón, Paulina Chinchilla-López, Oscar Ramírez-Pérez and Nahum Méndez-Sánchez

-González JA Garza AA Portal vein thrombosis in patients with cirrhosis: Just a common finding or a predictor of poor outcome? Ann Hepatol 2016 6 902 6 8 Nonami T, Yokoyama I, Iwatsuki S, Starzl TE. The incidence of portal vein thrombosis at liver transplantation. Hepatology1992; 5: 1195–8. Nonami T Yokoyama I Iwatsuki S Starzl TE. The incidence of portal vein thrombosis at liver transplantation Hepatology 1992 5 1195 8 9 Ogren M, Bergqvist D, Bjorck M, Acosta S, Eriksson H, Sternby NH. Portal vein thrombosis: Prevalence, patient characteristics and lifetime risk: A

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Yuqiao Wang, Ying Zhou and Zhiyuan Hu

primary studies carried out in laboratories have been reported as valid and effective steps to proceed to further clinical applications. Application of CTCs in breast cancer diagnosis In March 2013, Dawson et al . revealed a clear relevance between the concentration of CTCs and expected lifetime as well as the comparison between the sensitivity of three different biomarkers in diagnosis of breast cancer: Cancer Antigen 15-3 (CA 15-3), cell-free ctDNA, and CTCs.[ 7 ] In this study, a targeted or whole-genome sequencing to track alternation in somatic genome

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Des Crowley, Walter Cullen, Eamon Laird, John S. Lambert, Tina Mc Hugh, Carol Murphy and Marie Claire Van Hout

. [ 10 ] Contrary to what might be expected, the impact of self-declared drug and alcohol instability did not have a significant impact on fibroscan score. Ongoing alcohol misuse in chronically HCV infected individuals is associated with more severe liver disease. [ 10 ] Separating drug and alcohol stability as risks may have yielded a different result, but this finding is in keeping with poly-drug use pattern of this cohort and the tendency to substitute alcohol and illicit drug use over a lifetime of addiction and drug abuse. The high levels of self-declared drug