Search Results

You are looking at 1 - 2 of 2 items for :

  • Surgery, other x
Clear All
Open access

Maria Siemionow and Mikaël Hivelin

Face Transplantation: Clinical Application of the Concept

The face allotransplantation is a unique procedure, requiring a lifetime immunosuppressive therapy, and as such brings an ethical debate among medical societies and general public. The indications for this procedure have to be considered when the classic reconstructive procedures failed, and the patients are left with debilitating defects precluding them from normal social life.

The transplantation protocol must be approved and registered by the institutional review board and health agencies. It is crucial that a thorough assessment of the patient for each indication will be performed by a multidisciplinary team and panel of experts in the field of plastic and reconstructive surgery, maxillo facial surgery, immunology of transplantations and psychiatry. The thorough psychiatric and psychological evaluation of potential candidates is mandatory, as well as evaluation by ethic experts.

Numerous experimental models and extensive anatomical studies in cadaver model lead to the clinical success of face transplantation, raising a complex ethical question despite the fact that it is an important progress in plastic and reconstructive surgery.

Three face transplantations have been performed since 2005. The transplants differed and were tailored, to match the extend of each patient facial defect.

In this article we present the clinical cases of face transplantation based on our experience and dissections studies and a literature review.

Open access

Alexandra Stănescu, Imre Benedek, Mirabela Morariu, Mihaela Rațiu, Ramona Zavate, András Mester and Theodora Benedek

gender on outcomes of young AMI patients (VIRGO) study. Circulation . 2015;131:1971. 4. Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. J Am Coll Cardiol . 2012;60:1581-98. 5. Lloyd-Jones DM, Larson MG, Leip EP, et al. Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation . 2002;106:3068-3072. 6. Smith SC Jr, Blair SN, Bonow RO, et al. AHA/ACC Scientific Statement: AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic