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Musculoskeletal Outcomes from Chronic High-Speed High-Impact Resistive Exercise

countermeasures that sought to abate musculoskeletal losses (Kramer et al., 2017; Trappe et al., 2007). Those countermeasures included flywheel-based resistive exercise (Trappe et al., 2007) and high-intensity jump training (Kramer et al., 2017). Results showed that concurrent exercise reduced muscle mass and strength losses in those who received the experimental treatment as compared to bed-rested controls, yet neither countermeasure addressed bone losses, which is an important in- and postflight concern (Kramer et al, 2017; Trappe et al., 2007). However, a recent study with

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Investigation of Murine T-Cells and Cancer Cells under Thermal Stressors and 2D Slow Rotating System Effects as a Testbed for Suborbital Flights

Introduction There is a large body of research ( Licato and Grimm, 1999 ; Uva et al., 2002 ; Gridley et al., 2009 ; Singh et al., 2010 ; Thiel et al., 2012 ; Hauschild et al., 2014 ; Martinez et al., 2015 ; Nickerson et al., 2016 ) showing that exposure to microgravity leads to suppressed immunity in both rodents and humans. The downregulation of the immune system is measured by a decreased number of T-cells, alterations in immune cell subsets, epigenetic regulation, slower proliferation rate, and other immunological parameters. Altered gravity has

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