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Rosiglitazone-induced changes in the oxidative stress metabolism and fatty acid composition in relation with trace element status in the primary adipocytes

). Therefore, in this study, we aimed to investigate fatty acid composition, oxidative stress metabolism and their relation to the trace and mineral levels to reveal molecular mechanisms which control BAT into WAT conversion. Materials and Methods Materials Protease inhibitor cocktail was obtained from Sigma-Aldrich (Germany). Glucose-6-phosphate (G6P), sodium phosphate monobasic and dibasic, 6-phosphogluconate (6-PG), reduced nicotinamide adenine dinucleotide phosphate (NADPH + H + ), oxidized glutathione (GSSG), glutathione reductase (GR), reduced glutathione (GSH

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