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Luisa Maria Bellussi, Desiderio Passali, Emanuela Vesperini, Serena Cocca, Giulio Cesare Passali, Albera Roberto, Pasquale Cassano, Domenico Rosario Cuda, Michele De Benedetto, Gaetano Motta, Giuseppe Panetti, Marco Piemonte, Lorenzo Salerni, Felice Scasso and Giancarlo Vesperini

REFERENCES 1. Hosokawa T, Kikuchi Y, Nikoh N, Shimada M, Fukatsu T. Strict host-symbiont cospeciation and reductive genome evolution in insect gut bacteria. PLoS Biol. [Internet]. 2006;4(10):e337. Available from: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0040337 . https://doi.org/10.1371/journal.pbio.0040337 . 2. Nicholson JK, Holmes E, Kinross J, Burcelin R, Gibson G, Jia W, et al. Hostgut microbiota metabolic interactions. Science. 2012;336(6086):1262-7. DOI: 10.1126/science.1223813. Epub 2012 Jun 6. 3. Regev

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Raluca Dumache, Alexandru Florin Rogobete, Dorel Sandesc, Ovidiu Horea Bedreag, Veronica Ciocan, Camelia Muresan, Adrian Tudor Stan, Mihai Sandesc, Anca Dinu, Sonia Elena Popovici and Alexandra Enache

patients with primary and metastatic breast cancer. Breast Cancer Res . 2010;12:R90. 29. Guo Z, Maki M, Ding R, Yang Y, Zhang B, Xiong L. Genome-wide survey of tissue-specific microRNA and transcription factor regulatory networks in 12 tissues. Sci Rep . 2014;4. 30. Sood P, Krek A, Zavolan M, Macino G, Rajewsky N. Cell-type-specific signatures of microRNAs on target mRNA expression. Proc Natl Acad Sci USA . 2006;103:2746-2751. 31. Bloomston M, WL F, Petrocca F, et al. MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal

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Andreea Catana, Alma Maniu, Doinel Radeanu, Radu A. Popp, Roxana F. Ilies and Iuliu V. Catana

susceptibility loci in ethnically diverse populations. Nat Genet., 1997;15(4):389-392. 24. Dizier M.H., Besse-Schmittler C., Guilloud-Bataille M., et al. - Genome screen for asthma and related phenotypes in the French EGEA study. Am J Respir Crit Care Med., 2000;162(5):1812-1818. 25. Gao P.S., Kawada H., Kasamatsu T., et al. - Variants of NOS1, NOS2, and NOS3 genes in asthmatics. Biochem Biophys Res Commun., 2000;267(3):761-763. 26. Leung T.F., Liu E.K., Tang N.L., Ko F.W., Li C.Y., Lam C.W., Wong G.W. - Nitric oxide synthase