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Associations of biochemical changes and maternal traits with mutation 1843 (C>T) in the RYR1 gene as a common cause for porcine stress syndrome

-producing biochemical pathways [ 3 ]. In individuals susceptible to stress, it is generally accepted that increased level of either sarcoplasmic or myofibrillar-free calcium is the biochemical cause of the syndrome [ 11 ]. Thus, the main biochemical expression of PSS is intracellular deficit of Ca 2+ that is mainly stored in terminal cisternae of sarcoplasmic reticulum where it is bound to the calcium-binding protein calsequestrin [ 12 ]. Total plasma calcium concentrations increase during a PSS crisis. Sarcoplasmic proteins also leak from muscle fibers during an acute episode

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Organic dust exposure in veterinary clinics: a case study of a small-animal practice in Portugal

.5893.00289 19. Brown J, Gordon T, Price O, Asgharian B. Thoracic and respirable particle definitions for human health risk assessment. Part Fibre Toxicol 2013;10:12. doi: 10.1186/1743-8977-10-12 20. Reponen T. Sampling for microbial determinations. In: Viegas C, Viegas S, Quintal Gomes A, Taubel M, Sabino R, editors. Exposure to microbiological agents in indoor and occupational environments. Cham: Springer International Publishing AG; 2017. p. 85-96. 21. Duquenne P. On the identification of culturable microorganisms

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Toxicological Effects of Weapons of Mass Destruction and Noxious Agents in Modern Warfare and Terorrism

;8:202-4. Woese CR, Magrun LJ, Gupta R, Siegel RB, Stahl DA, Kop J, Crawford J, Brosius J, Gutell R, Hogan JJ, Noller HF. Secondary structure model for bacterial 16S ribosomal RNA: phylogenetic, enzymatic and chemical evidence. Nucleic Acids Res 1980;8:2275-93. Vučemilović A, Petranović M, Popović Hadžija M, Korolija M, Zahradka K, Hadžija M. Application of 16S ribosomal RNA sequence in the identification of laboratory strains of Bacillus species in the warfare polymer fibre. U: 4 th Croatian Congress of Microbiology with International Participation

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Occupational exposure to bioburden in Portuguese bakeries: an approach to sampling viable microbial load

-approach protocol for the characterization of occupational exposure to organic dust - swine production case study. Toxics 2018;6:5. doi: 10.3390/toxics6010005 21. Brown JS, Gordon T, Priceand O, Asgharian B. Thoracic and respirable particle definitions for human health risk assessment. Part Fibre Toxicol 2013;10:12. doi: 10.1186/1743-8977-10-12 22. Chmielowiec-Korzeniowska A, Tymczyna L, Drabik A, Krzosek L. Microbial contamination level of air in animal waste utilization plants. Ann Agric Environ Med 2016;23:54-8. doi: 10

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Proteomics study of the antifibrotic effects of α-mangostin in a rat model of renal fibrosis

have been reported. An investigation of whether AM can attenuate renal fibrosis and aid in processes of protection against and reversal of tissue damage, and the mechanisms of AM action in any such attenuation is warranted. To determine whether AM can disrupt progression of renal fibrosis in a rat model of the disease, histopathology using Sirius Red collagen fiber staining, which allows us to determine the relative amount of collagen fibers in renal tissue, and proteomic analysis of protein marker expression was used to understand better potential mechanisms of AM

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Electromagnetic fields at a mobile phone frequency (900 MHz) trigger the onset of general stress response along with DNA modifications in Eisenia fetida earthworms

, Mitta G, Leroux R, Lemière S, Leprêtre A, Vandenbulcke F. The strong induction of metallothionein gene following cadmium exposure transiently affects the expression of many genes in Eisenia fetida: a trade-off mechanism? Comp Biochem Physiol C Toxicol Pharmacol 2007;144:334-41. doi: 10.1016/j.cbpc.2006.10.007 20. Brulle F, Cocquerelle C, Mitta G, Castric V, Douay F, Leprêtre A, Vandenbulcke F. Identification and expression profile of gene transcripts differentially expressed during metallic exposure in Eisenia fetida coelomocytes. Dev Comp Immunol

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Neuroradiological, neurophysiological and molecular findings in infantile Krabbe disease: two case reports

time ( Figure 2 ), demonstrated increased signal of the white matter around the occipital horns of the lateral ventricles with enlargement of lateral ventricles and the subarachnoid spaces bilaterally. These lesions of the white matter expanded radially, while additional small lesions in the anterior fiber bundles of the pons and the brainstem. Figure 2 Brain MRI of second patient at the age of 18 months (T2 weighted sequences TR/TE 4510/119). Note the increased signal in the periventicular white matter around the occipital horns of the lateral ventricles with

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Glutathionylation: a regulatory role of glutathione in physiological processes

130. Blaine SA, Meyer AM, Hurteau G, Wick M, Hankin JA, Murphy RC, Dannenberg AJ, Geraci MW, Subbaramaiah K, Nemenoff RA. Targeted over-expression of mPGES-1 and elevated PGE2 production is not sufficient for lung tumorigenesis in mice. Carcinogenesis 2005;26:209-17. doi: 10.1093/carcin/bgh302 131. Jakobsson P-J, Thorén S, Morgenstern R, Samuelsson B. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci USA 1999;96:7220-5. PMCID: PMC

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Anatomic variations of coronary arteries: origins, branching patterns, and abnormalities

artery; RCA, right coronary artery Figure 7 ( A ) One site of the myocardial bridge on the AIA. ( B ) Two sites on the AIA. AIA, anterior interventricular artery Discussion Identification of the dominant pattern of coronary arteries has clinical importance particularly from the functional impact of myocardial ischemia [ 3 ]. The prevalence of right dominance had been reported to be 40%–80% [ 3 , 6 , 7 , 8 ], left dominance 6.8%–18.57% [ 7 , 9 , 10 ], and codominance 10%–42.5% [ 8 , 11 , 12 ]. In the present study, the prevalence of right

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Epigenetic signature of chronic maternal stress load during pregnancy might be a potential biomarker for spontaneous preterm birth

, including stress response and mRNA processing [ 39 ]. Many other studies examined other types of biomarkers for preterm birth such as cytokines and other metabolites in maternal serum, but biomarkers that examine DNA methylation changes may allow for earlier identification of those at increased risk for preterm birth. DNA methylation changes are also more suitable to screening with next-generation sequencing panels that utilize standardized chemistry, and are able for more rapid and reproducible assessment of multiple biomarkers. However, evidence of preterm birth

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