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Early mobilization for mechanically ventilated patients in the intensive care unit: a systematic review and meta-analysis

identification of included studies. 3 Results 3.1 Study selection In this systematic review, the search in all databases yielded 655 potentially relevant articles. Of those, seven registered clinical trials have been completed, but there were no study results posted. After screening the titles and/or abstract, 30 full-text articles were selected ( Figure 1 ). Twenty-two studies failed to meet the inclusion criteria, and thus, eight studies (seven RCTs and one CCT) were included in the qualitative synthesis 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 and five 20

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Proteomics study of the antifibrotic effects of α-mangostin in a rat model of renal fibrosis

have been reported. An investigation of whether AM can attenuate renal fibrosis and aid in processes of protection against and reversal of tissue damage, and the mechanisms of AM action in any such attenuation is warranted. To determine whether AM can disrupt progression of renal fibrosis in a rat model of the disease, histopathology using Sirius Red collagen fiber staining, which allows us to determine the relative amount of collagen fibers in renal tissue, and proteomic analysis of protein marker expression was used to understand better potential mechanisms of AM

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Anatomic variations of coronary arteries: origins, branching patterns, and abnormalities

artery; RCA, right coronary artery Figure 7 ( A ) One site of the myocardial bridge on the AIA. ( B ) Two sites on the AIA. AIA, anterior interventricular artery Discussion Identification of the dominant pattern of coronary arteries has clinical importance particularly from the functional impact of myocardial ischemia [ 3 ]. The prevalence of right dominance had been reported to be 40%–80% [ 3 , 6 , 7 , 8 ], left dominance 6.8%–18.57% [ 7 , 9 , 10 ], and codominance 10%–42.5% [ 8 , 11 , 12 ]. In the present study, the prevalence of right

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Neuroprotective effect of Erigeron Breviscapus (vant) Hand-mazz extract on retinal ganglion cells in rabbits with chronic elevated intraocular pressure

A, Centofanti M, Mattei E, De Gregorio A, Aloe L, et al. Histopathological evaluation of retinal damage during intraocular hypertension in rabbit: involvement of ganglion cells and nerve fiber layer. Graefes Arch Clin Exp Ophthalmol. 1996; 234 (Suppl 1):S209-13. 16. Zhu MD, Cai FY. Development of experimental chronic intraocular hypertension in the rabbit. Aust N Z Ophthalmol. 1992; 20:225-34. 17. Heijl A, Leske MC, Bengtsson B, Hyman L, Bengtsson B, Hussein M, et al. Reduction of intraocular pressure and glaucoma progression

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Pathophysiology of parkinsonian tremor: a focused narrative review

, brainstem, and higher brain [ 16 ]. The simplest loop is the peripheral monosynaptic stretch reflex loop where the Ia afferent fibers from the muscle spindle synapse directly with the α motor neurons in the spinal cord, which send axons to the extrafusal muscle fibers [ 16 ]. Theoretically, flexion movements will stretch and cause afferent volley eliciting reflexes in the antagonistic extensors. When an extensor muscle is activated, a similar pattern occurs, causing an afferent volley to the flexors [ 23 ]. These reflex loops are then connected and oscillate over time

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