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First evidence of the P-glycoprotein gene expression and multixenobiotic resistance modulation in earthworm

evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011;28:2731-9. doi: 10.1093/molbev/msr121 25. Hillis DM, Bull JJ. An empirical test of bootstrapping as a method for assessing confidence in phylogenetic analysis.Syst Biol 1993;42:182-92. doi: 10.1093/sysbio/42.2.182 26. Le SQ, Gascuel O. An improved general amino-acid replacement matrix. Mol Biol Evol 2008;25:1307-20. doi: 10.1093/molbev/msn067 27. Abascal F, Zardoya R, Posada D. ProtTest: Selection of

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CYP2D6 allele distribution in Macedonians, Albanians and Romanies in the Republic of Macedonia

cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data. Phar-macogenetics. 1999; 9(6): 669-682. Gaedigk A Gotschall RR Forbes NS Simon SD Kearns GL Leeder JS Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data Phar-macogenetics 1999 9 6 669 682 15 Sistonen J, Sajantila A, Lao O, Corander J, Barbujani G, Fuselli S. CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure. Pharmacogenet

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Novel insights into genetics and clinics of the HNF1A-MODY

, Brockmoller J, Tzvetkov M. Hepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 gene. J Pharmacol Exp Ther 347, 181–192, 2013. O’Leary NA, Wright MW, Brister JR, Ciufo S, Haddad D, McVeigh R, Rajput B, Robbertse B, Smith-White B, AkoAdjei D, Astashyn A, Badretdin A, Bao Y, Blinkova O, Brover V, Chetvernin V, Choi J, Cox E, Ermolaeva O, et al. Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation. Nucleic

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