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Therapy of a schizoaffective disorder as a risk factor of perinatal complications and fetal developmental disorders

Abstract

Introduction: Schizoaffective disorder is described as a combination of symptoms of schizophrenia and mood disorder components. It is estimated that in 2009 in Poland over 30 thousands women were treated in outpatient care because of schizotypical disorders, also in 2009, over 5,5 thousands Polish women, were hospitalised because of the same reason.

Material and method: We searched through whole medical documentation of the patient, which were available at the Department of Psychiatry and Gynaecology. We mainly focused on the last hospitalization of the woman. We found research connected to our subject on Science Direct website.

Discussion: A 34-year-old woman was admitted to Department of Psychiatry, patient was 14 weeks pregnant. Family described her behaviour as verbally and physically aggressive and dysphoric which forced her parents to take woman to the hospital. It was her third hospitalization. Pharmacotherapy was insufficient to improve the mental state of the woman. Doctors decided to carry out a series of electroconvulsive treatments (10 procedures). When woman was 36 weeks pregnant, there was a leak of green amniotic fluid and it was necessary to perform a caesarean section. A newborn required mechanical ventilation, had decreased muscle tone and facial dysmorphic features, also defect of the atrial septum was found.

Conclusions: Pregnant women with psychiatric disorders should be all considered high risk. It means that they need multidisciplinary care – psychiatrist, gynaecologist, neonatologist or other specialists, in order to stay in a good condition mentally and physically during pregnancy.

Open access
Clozapine-resistant schizophrenia – non pharmacological augmentation methods

Findings From a Double-Blind-Randomized Trial. Schizophr. Bull. 42(1), 250–257 (2016). 78. Nitsche MA, Niehaus L, Hoffmann KT, Hengst S, Liebetanz D, Paulus W et al. MRI study of human brain exposed to weak direct current stimulation of the frontal cortex. Clin. Neurophysiol. 2004; 115 (10): 2419–2423 79. Nitsche MA, Doemkes S, Karaköse T, Antal A, Liebetanz D, Lang N et al. Shaping the effects of transcranial direct current stimulation of the human motor cortex. J Neurophysiol. 2007;97(4):3109-17 80. Boggio PS, Rigonatti SP, Ribeiro RB, Myczkowski ML

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Depression and anxiety disorders in people with diabetes

Abstract

Introduction: As the global number of diabetes and the burden of depression together with other mental disorders increases, there is a need for better understanding of the connection between these diseases. In patients with diabetes, mental disorders are more common than in the general population, especially anxiety disorders and depression, which are often difficult to detect by health professionals.

Material and methods: Using the keywords searched in the international bibliographic databases: Embase, Medline, Science Direct, Web of Science. We analyzed clinical trials published in English and international journals

Results: Patients with diabetes are exposed to serious physical and mental complications. The occurence of depression and psychiatric disorders among people with diabetes was twice as frequent as in the general population. There are also studies showing a higher risk of suicide among people with diabetes. In addition, patients with both diseases, diabetes and depression, had an increased risk of cardiovascular complications and increased mortality and higher costs of health care. Diabetic patients have increased incidence of anxiety disorders in relation to non-diabetic patients by 20%.

Conclusion: Further researches and integration of medical and psychological treatment are needed. Cooperation between psychiatrists and diabetologists can reduce mental and physical harm in patients with diabetes.

Open access