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J. Šimková, M. Milkovičová, M. Valko-Rokytovská, Z. Kostecká, E. Bencúrová, L. Pulzová, Ľ. Čomor and M. R. Bhide

SlyD with nickel ions illuminates the mechanism of regulation of its peptidyl-prolyl isomerase activity. FEBS J. , 276, 4529—4544. 23. Mejáre, M., Bülow, L., 2001: Metal-binding proteins and peptides in bioremediation and phytoremediation of heavy metals. Trends Biotechnol. , 19, 67—73. 24. Mlynarcik, P., Bencurova, E., Madar, M., Mucha, R., Pulzova, L., Hresko, S., Bhide, M., 2012: Development of simple and rapid elution methods for proteins from various affinity beads for their direct MALDI-TOF downstream application. J. Proteomics , 75, 4529

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Yong-Jie Yang, Zeng-Shan Liu, Shi-Ying Lu, Pan Hu, Chuang Li, Waqas Ahmad, Yan-Song Li, Yun-Ming Xu, Feng Tang, Yu Zhou and Hong-Lin Ren

strain can induce antibodies that interfere with the serological tests leading to failure in discriminating vaccinated animals from naturally infected ones ( 3 , 18 ). Thus, it is necessary to search for diagnostic biomarkers allowing to distinguish between vaccinated and infected animals. Cdc42 is a small GTPase, a member of the Rho subfamily, which can act as a molecular switch to control signal transduction pathways by cycling between an inactive state (GDP-bound) and an active state (GTP-bound) ( 10 ). In GTP-binding form, Cdc42 interacts with its downstream

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Małgorzata Samorek-Pieróg, Jacek Karamon and Tomasz Cencek

diagnosis of an adult intestinal Taenia solium infection can be reached by enzyme-linked immunoelectrotransfer blot method (EITB). This serological test provides diagnosis of species-specific circulating antibodies, and there are no cross-reactions with another parasitical infection. This provides an opportunity to conquer some of the troubles that persist with coproantigen examination ( 2 ). Specificity of this method was considered to be 100% and sensitivity about 95% ( 14 ). The principle of this test is to detect antibodies directed versus excretion-secretion (ES