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Open access

Li Han

, 79:3922-3933. 17 Barker JR, Koestler BJ, Carpenter VK, et al . Sting-dependent recognition of cyclic diAMP mediates type I interferon responses during Chlamydia trachomatis infection. MBio, 2013, 4: e00018-00013. 18 Burian K, Endresz V, Deak J, et al . Transcriptome analysis indicates an enhanced activation of adaptive and innate immunity by chlamydia-infected murine epithelial cells treated with interferon gamma. J Infect Dis, 2010, 202:1405-1414. 19 Ishihara T, Aga M, Hino K, et al . Inhibition of Chlamydia trachomatis growth by human

Open access

Jin Zhang

Brucella DCs include unique antigen-presenting cells with the strongest organism function and can activate resting T cells. DCs can efficiently take up, process, and present antigens. Immature DCs exhibit strong mobility, whereas the mature ones can effectively activate naïve T cells. DCs act as the central link in starting, regulating, and maintaining the immune response. When Brucella invades organisms, cyclic β-1,2-glucan in the bacterium seriously infects the DCs, causing the immune balance of CD4 + T cells to tend toward Th2 cell subsets. This condition can aid