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Correlations Between Regional Accumulation of Calcium in the Culprit Arteries and Plaque Burden in Acute Coronary Syndromes

Abstract

Introduction: The association between a high calcium score at the level of the unstable coronary lesions and the different characteristic of culprit lesions which result in an acute coronary syndrome (ACS) has not been described yet. We aimed to study the correlation between the accumulation of calcium within the vessel wall of a coronary artery and the plaque burden of culprit lesions that develop an acute coronary event. Material and methods: A total of 45 patients with ACS (22 unstable angina, 23 nonST elevation myocardial infarction) underwent 64-slice CCTA. In all patients a complex CT analysis of the culprit plaques was performed and the calcium score for each coronary artery was computed. Results: We found a significant correlation between a calcium score higher than 100 and the plaque volume (r = 0.85. p = 0.01). Selecting a cut-off value of 100 HU for regional calcium score at the level of the coronary artery, we found that those arteries with Ca score higher than 100 presented significantly larger plaque volumes than the ones with calcium score below 100 (110.8 ml vs 82.4 ml, p <0.0001 for left anterior descending artery, 111.09 ml vs 82.5 ml, p = 0.0005 for circumflex artery, and 132.78 ml vs 76.23 ml for right coronary artery). Conclusion: Our data shows that in ACS, the severity of the culprit lesions correlates with regional accumulation of calcium within the vessel wall.

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Risk Factors for Eating Disorders Among Male Adolescent Athletes / Dejavniki Tveganja Motenj Hranjenja Med Športniki V Adolescenci

, 2008. 26. Cole TJ, Flegal KM, Nicholls D, Jackson AA. Body mass index cut offs to define thinness in children and adolescents: international survey. BMJ 2007; 335: 194. 27. Mathews DK, Fox EL. The physiological basis of physical education and athletics. Philadelphia: W. B. Saunders, 1976. 28. Smolak L, Murnen SK, Ruble AE. Female athletes and eating problems: a meta-analysis. Int J Eat Disord 2000; 27: 371-80. 29. Fulkerson JA, Keel PK, Leon GR, Dorr T. Eating-disordered behaviors and personality

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Individual and contextual factors of nulliparas’ levels of depression, anxiety and fear of childbirth in the last trimester of pregnancy: intimate partner attachment a key factor?

screening instrument, the cut-off scores of 12/13 usually designate major depression, whereas scores from 9 to 11 indicate mild depression levels in need of further assessment ( 31 ); Cronbach α=0.83. 2.3.3 Anxiety The Zung Anxiety Scale ( 32 ) consists of 20 items that test the participants’ autonomic, motor, cognitive and other anxiety symptoms. For each item, the participants choose one of the following answers: a little of the time, some of the time, good part of the time, most of the time; Cronbach α=0.76. 2.3.4 Fear of Childbirth Fear of childbirth: a 6

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How Informative are the Vertical Buoyancy and the Prone Gliding Tests to Assess Young Swimmers' Hydrostatic and Hydrodynamic Profiles?

How Informative are the Vertical Buoyancy and the Prone Gliding Tests to Assess Young Swimmers' Hydrostatic and Hydrodynamic Profiles?

The aim of this research was to develop a path-flow analysis model to highlight the relationships between buoyancy and prone gliding tests and some selected anthropometrical and biomechanical variables. Thirty-eight young male swimmers (12.97 ± 1.05 years old) with several competitive levels were evaluated. It were assessed the body mass, height, fat mass, body surface area, vertical buoyancy, prone gliding after wall push-off, stroke length, stroke frequency and velocity after a maximal 25 [m] swim. The confirmatory model included the body mass, height, fat mass, prone gliding test, stroke length, stroke frequency and velocity. All theoretical paths were verified except for the vertical buoyancy test that did not present any relationship with anthropometrical and biomechanical variables nor with the prone gliding test. The good-of-fit from the confirmatory path-flow model, assessed with the standardized root mean square residuals (SRMR), is considered as being close to the cut-off value, but even so not suitable of the theory (SRMR = 0.11). As a conclusion, vertical buoyancy and prone gliding tests are not the best techniques to assess the swimmer's hydrostatic and hydrodynamic profile, respectively.

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25th Hellenic conference of Clinical Oncology

side effects during as well as post Everolimus treatment. TUMOR MUTATIONAL BURDEN (TMB): DETERMINATION, CUT-OFFS AND ITS EMERGING IMPORTANCE IN IMMUNOTHERAPIES Tsaousis G. 1 , Papadopoulou E. 1 , Fotiou D. 1 , Tsantikidi K. 1 , Metaxa-Mariatou V. 1 , Stamou E. 1 , Floros T. 2 , Trafalis D. 3 , Anagnostopoulos A. 3 , Fassas A. 4 , Diamantidou E. 5 , Giassas S. 6 , Andreadis X. 7 , Gkioulmpasanis I. 8 , Tsiatas M. 9 , Tzaninis D. 9 , Nasioulas G. 1 1 Genekor Medical SA, Athens, Greece 2 Athens Naval and Veterans Hospital, Athens, Greece 3 Errikos

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CA19-9 serum levels predict micrometastases in patients with gastric cancer

micrometastases and preoperative CA19-9 serum levels to determine the cut-off level for micrometastases detection, along with the respective sensitivities and specificities. Finally, the prognostic value of this cut-off for CA19-9 serum levels was investigated for a group of patients with node-negative gastric cancer. Patients and methods Between 1992 and 2013, a total of 1,129 patients underwent surgery for gastric cancer at the University Clinical Centre Maribor, Slovenia. From these, only node-negative patients with complete clinicopathological records and

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Modelling and Predicting Backstroke Start Performance Using Non-Linear And Linear Models

processing The surface and underwater video images were independently digitised frame-by-frame by the same operator using the Ariel Performance Analysis System (Ariel Dynamics Inc., USA) (e.g. Sanders et al., 2016 ). Image coordinates were transformed into 2D object-space coordinates with a Direct Linear Transformation algorithm ( Abdel-Aziz and Karara, 1971 ) with six calibration points ( de Jesus et al., 2013 , 2015 ) and a 5 Hz cut-off value has been selected for data filtering (2 nd order low-pass digital filter; de Jesus et al., 2015 ) according to residual

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Left main stenting induced flow disturbances on ascending aorta and aortic arch

Introduction Effects of coronary stenting techniques are generally investigated regarding wall shear stress (WSS) or turbulence of flow at the lesion or bifurcation sites. [ 1 , 2 ] Recently, we speculated that ostial left main (LM) stenting potentially induces turbulence in the aortic wall near to the LM ostium. [ 3 ] Potential impact on the ascending aorta and arch have never been evaluated despite the fact that it would be logical that any turbulence induced outside the coronary tree can propagate at a certain distance within the aortic vasculature

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Analysis of peripheral artery velocity tracing in a porcine model

parameters in the diagnosis of renal artery stenosis: a study to validate and optimize cut-off points. Arq Bras Cardiol 2006; 87 : 321-8. Kawarada O, Yokoi Y, Takemoto K, Morioka N, Nakata S, Shiotani S. The performance of renal duplex ultrasonography for the detection of hemodynamically significant renal artery stenosis. Catheter Cardiovasc Interv 2006; 68 : 311-8. Smet AA, Ermers EJ, Kitslaar PJ. Duplex velocity characteristics of aortoiliac stenoses. J Vasc Surg 1996; 23 : 628

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Non-invasive evaluation of fluid dynamic of aortoiliac atherosclerotic disease: Impact of bifurcation angle and different stent configurations

. Through a cut-out, the obtained ring of the stent was propagated axially to create the full-length, expanded model. In our models, the artery walls and plaque components were assumed to be isotropic, linear and elastic with a constant Young’s modulus ( E ), density and Poisson’s ratio. For stent simulation, devices were modelled as a shell-type tube; the mechanical properties such as density and Poisson’s ratio were in accordance with the reported technical properties of the stent. The arterial wall thickness was considered to be constant at 0.5 mm. A 3-D reconstruction

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