References Burg MB. (2002). Response of renal inner medullary epithelial cells to osmotic stress. Comp Biochem Physiol A Mol Integr Physiol 133 : 661-666. Cai Q, Dmitrieva NI, Michea LF, Rocha G, Ferguson D and Burg MB. (2003). Toxicity of acetaminophen, salicylic acid, and caff eine for fi rst-passage rat renal inner medullary collecting duct cells. J Pharmacol Exp Ther 306 : 35-42. Ferraro PM, Costanzi S, Naticchia A, Sturniolo A and Gambaro G. (2010). Low level exposure to cadmium increases the risk of
Eun-Kee Park, Sally K. Mak and Bruce D. Hammock
M. Veera Prasad, Amit Agrawal, S. Satish Kumar and B.V. Subrahmanyan
References 1.Shaban S, Eid H, Barka E, Abu-Zidan F. Towards a national trauma registry for the United Arab Emirates. BMC Research Notes 2010;3:187. 2.Ringdal KG, Lossius HM, Jones JM, et al. Collecting core data in severely injured patients using a consensus trauma template: an international multicentre study. Crit Care 2011;15:R237. 3.Dick WF, Baskett PJ. Recommendations for uniform reporting of data following major trauma--the Utstein style. A report of a working party of the International Trauma Anaesthesia
Gergő Ráduly, Zsuzsánna Pap, Loránd Dénes, Annamária Szántó and Zoltán Pávai
development by the Mdm2/Mdm4-p53 axis. J Mol Cell Biol. 2017; 9:26-33. 5. Liu H, Wintour EM - Aquaporins in development – a review. Reprod Biol Endocrinol. 2005;3:18. 6. Hua Y, Jiang W, Zhang W et al - Expression and significance of aquaporins during pregnancy. Front Biosci (Landmark Ed). 2013;18:1373-83. 7. Jung HJ, Kwon TH - Molecular mechanisms regulating aquaporin-2 in kidney collecting duct. Am J Physiol Renal Physiol. 2016; 311:1318–F1328. 8. Takata K, Matsuzaki T, Tajika Y et al - Localization and trafficking of aquaporin 2 in the kidney
Loredana Mariana Aftenie, Irina Franciuc, Alina Martinescu and Adina Honcea
References 1. FREEMAN B, POWELL J, BALL D, HILL L, CRAIG I, PLOMIN R. DNA by mail: an inexpensive and noninvasive method for collecting DNA samples from widely dispersed populations. Behav Genet. 1997;27:251-257. 2. KING IB, SATIA-ABOUTA J, THORNQUIST MD, BIGLER J, PATTERSON RE, KRISTAL AR, SHATTUCK AL, POTTER JD, WHITE E. Buccal cell DNA yield, quality, and collection costs: Comparison of methods for large-scale studies. Cancer Epidemiol Biomarkers Prev. 2002;11:1130-1133. 3. HANSEN TV, SIMONSEN
Amit Agrawal, M. Veera Prasad, S. Satish Kumar, B. V. Subrahmanyan, P. N. Harisha and G. Malleswara Rao
. The goals, development, and use of trauma registries and trauma data sources in decision making in injury. The Surgical clinics of North America 1995;75:305-326. 22. Moore L, Clark DE. The value of trauma registries. Injury 2008;39:686-695. 23. Mehmood A, Razzak JA. Trauma registry—needs and challenges in developing countries. JPMA The Journal of the Pakistan Medical Association 2009;59:807-808. 24. Schuurman N, Cinnamon J, Matzopoulos R, Fawcett V, Nicol A, Hameed SM. Collecting injury surveillance data in low- and middle-income countries: the Cape Town
Surg Pathol. 2010;34:1233-40. 3. Amin MB, MacLennan GT, Gupta R, Grignon D, Paraf F, Vieillefond A, Paner GP, Stovsky M, Young AN, Srigley JR, Cheville JC. Tubulocystic carcinoma of the kidney: Clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma. Am J Surg Pathol. 2009;33:384-92. 4. MacLennan GT, Farrow GM, Bostwick DG. Low-grade collecting duct carcinoma of the kidney: Report of 13 cases of low-grade mucinous tubulocystic renal carcinoma of possible collecting duct origin. Urology. 1997
Vărgău M., Iliescu D.M., Dina C., Ionescu C. and Bordei P.
ed. (pp. 298-300). Paris: Ed. Pradel 5. Drews U. (1993). Atlas de poche d’embryologie. (pp. 332). Paris: Ed. Flammarion 6. Campbell JE. (1967). Ureteral peristalsis in duplex renal collecting systems. Am J Roentgenol Radium Ther Nucl Med. 99, 577-584 7. Prakash, Rajini T., Venkatiah J. & Bhardwaj A.K. (2011). Double Ureter and Duplex System. A Cadaver and Radiological Study. Urol J. 8, 145-148 8. Burych M.P. (2002). Renal excretory sector. Surg.Radiol.Anat. 24, 201-204
Martina Svobodová, Helena Dračínská, Markéta Martínková, Jiří Hudeček, Petr Hodek, Eva Frei and Marie Stiborová
gasoline engine exhausts and some nitroarenes. Monograph on the Evaluation of the carcinogenic risk to humans. Diesel Exhaust and Some Nitroarenes. Vol. 46, IARC, Lyon. Mikšanová M, Novák P, Frei E and Stiborová M (2004a) Metabolism of carcinogenic 2-nitroanisole by rat, rabbit, porcine and human hepatic cytosol. Collect Czech Chem Commun 69 : 589-602. Mikšanová M, Šulc M, Rýdlová H, Schmeiser HH, Frei E and Stiborová M (2004b) Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its
Lica Melania Maria, Jakab Zoltan, Crainic Maria and Mihai Adriana
Insulin-dependent diabetes mellitus (IDDM) is a chronic disease with high incidence, especially in children, and for a better outcome the individual case management is required. The patient and his family can experience different levels of anxiety, with negative effects on disease evolution and prognosis.
Objectives: identify relevant factors which influence the case management of children with IDDM. The implementation of the results of this study will help to elaborate an efficient method of intervention for improving the treatment adherence and obtaining a better outcome of IDDM in children.
Methods: A semi-structured interview was done individually to 10 experts in diabetes for collecting their opinion concerning relevant factors that may influence treatment adherence and what are the characteristics of an efficient method of intervention.
Results: Majority of experts considered that the main factor which influences the outcome is doctor-patient relationship. The need of child, to feel that it is understood and protected, was considered that can directly motivate a better self-management and a good outcome. The increase of importance of individual resources of children with IDDM and accent on the quality of life of those children could be considered a starting point for creating a psychological clinic intervention in this field. The results were compared with scientific literature data.
Conclusions: understanding of the causes which have interfered negatively with therapeutic plan is a starting point for develop a clinical - psychological protocol for children with IDDM.
Domokos L, Ábrám Z, Sebesi Sz and Finta Hajnal
Introduction: In 2010 Romania was ranked fourth in the European Union regarding the prevalence of ethnobotanical drug use with psychotropic effect. The main purpose of our survey was to collect data on substance use and assess drug consumption habits among participants at the 2011 Peninsula Music Festival in Tîrgu Mureș, Romania. Material and method: The study was carried out as a cross-sectional survey in a sample of 256 persons, using an anonymous, self-administered structured questionnaire, containing questions about the consumption patterns of illegal psychoactive drugs, as well as sociodemographic data which could influence drug consumption (age, gender, educational level, marital status of parents). Results: Ethnobotanical drug consumption had the highest lifetime prevalence (37.7%), the second most often used drug was cannabis (marijuana) with a lifetime prevalence of 35.2%. Males and females differed significantly in the use of marijuana (p = 0.023) and ethnobotanical drugs (p = 0.008) in the last 12 months, male respondents used more of these psychoactive substances. In the case of children with divorced parents the last 12 months marijuana use (p = 0.032) and ethnobotanical drug use (p = 0.013) was significantly higher than in the case of children whose parents were not divorced. Conclusions: The survey results show the importance of the development of health education programs and drug-prevention strategies for vulnerable goups (festival visitors, minors, children with divorced parents)