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Endre Zima

References 1. Centers for Disease Control and Prevention (CDC). Statespecific mortality from sudden cardiac death - United States, 1999, MMWR Morb Mortal Wkly Rep, 2002;51:123-6. 2. Myerburg RJ, Castellanos A. Cardiac arrest and sudden cardiac death. Braunwald E, ed. Heart Disease: A Textbook of Cardiovascular Medicine. 5th ed. Philadelphia, Pa: WB Saunders; 1997:742-779. 3. de Vreede-Swagemakers JJ, Gorgels AP, Dubois-Arbouw WI, et al. Out-of-hospital cardiac arrest in the 1990’s: a populationbased study in the

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Theodora Benedek, Monica Marton Popovici and Dietmar Glogar

, et al. Favourable survival of in-hospital compared to out-of-hospital refractory cardiac arrest patients treated with extracorporeal membrane oxygenation: an Italian tertiary care centre experience. Resuscitation. 2012;83:579-83. doi: 10.1016/j.resuscitation.2011.10.013. 6. Dworschak M. Is extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest superior compared with conventional resuscitation? Crit Care Med. 2013;41:1365-6. doi: 10.1097/CCM.0b013e31828044c0. 7. Le Guen M, Nicolas-Robin A, Carreira S, et al. Extracorporeal life

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Shane Belvedere

arteriovenous fistula can be attempted [ 1 ]. Adjunctive measures include placement of an inferior vena cava (IVC) filter, and fasciotomy [ 8 ]. Given the high incidence of PE with PCD, IVC filter placement is an important measure to prevent further PE that may be a complication of treatment. Case report A previously healthy 46-year-old male, on no medications, presented following a pulseless electrical activity (PEA) arrest after collapsing at home. He was resuscitated and had the return of spontaneous circulation before arriving at the nearby tertiary care hospital

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Wojciech Dyk, Piotr Wolski, Piotr Szatkowski, Eugeniusz Szpakowski and Andrzej Biederman

Deep Hypothermic Circulatory Arrest During Pulmonary Thrombendarterectomy in Patients with Chronic Thrombembolic Pulmonary Hypertension

Chronic thrombembolic pulmonary hypertension is a rare complication of acute pulmonary embolism. Narrowing or closure of pulmonary arteries is the cause of pulmonary hypertension and results in right ventricular overload and failure. The treatment of choice is pulmonary thrombendarterectomy. Deep hypothermic circulatory arrest is a very important factor required for complete removal of the thrombembolic material from the pulmonary arteries during the operation.

The aim of the study was the evaluation of the effectiveness of the use of deep hypothermic circulatory arrest during pulmonary thrombendarterectomy in patients with chronic thrombembolic pulmonary hypertension.

Material and methods. Between October 1995 and October 2006 seventy patients were operated on. All of them were operated on with the use of deep hypothermic circulatory arrest. Deep hypothermia (18-19°C), pharmacotherapy, and neuromonitoring were used as a protection of the central nervous system during circulatory arrest.

Results. In fifty-seven patients out of seventy, complete thrombendarterectomy was performed (more than 75% of branches opened). The average pulmonary artery pressure and pulmonary vascular resistance were decreased, and cardiac output and index were increased. Six patients died (8.6%).

Conclusions. Complete thrombendarterectomy gives significant hemodynamical improvement in patients undergoing the operation. Deep hypothermic circulatory arrest during the operation does not cause significant neurological complications. Incomplete thrombendarterectomy may be the cause of right ventricular failure and death after the operation.

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Evelin Szabó, Diana Opincariu, Zsolt Parajkó, Noémi Mitra, Theodora Benedek and Imre Benedek

, Agewall S, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J . 2018;39:119-177. 5. Khera S, Kolte D, Gupta T, et al. Temporal Trends and Sex Differences in Revascularization and Outcomes of ST-Segment Elevation Myocardial Infarction in Younger Adults in the United States. J Am Coll Cardiol . 2015;66:1961-1972. 6. Atwood C, Eisenberg MS, Herlitz J, Rea TD. Incidence of EMS-treated out-of-hospital cardiac arrest in Europe. Resuscitation . 2005;67:75-80. 7. Dumas F

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Andreea Bărcan, Monica Chițu, Edvin Benedek, Nora Rat, Szilamer Korodi, Mirabela Morariu and Istvan Kovacs

;8:8032-41. 10. Park JS, Cha KS, Lee DS, et al. Culprit or multivessel revascularisation in ST-elevation myocardial infarction with cardiogenic shock. Heart. 2015;101:1225-32. 11. Mylotte D, Morice MC, Eltchaninoff H, et al. Primary percutaneous coronary intervention in patients with acute myocardial infarction, resuscitated cardiac arrest, and cardiogenic shock: the role of primary multivessel revascularization. JACC Cardiovasc Interv. 2013;6:115-25. 12. Ostenfeld S, Lindholm MG, Kjaergaard J, et al. Prognostic implication of out

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Raluca M. Tat, Adela Golea, Ştefan C. Vesa and Daniela Ionescu

Introduction Despite fifty years of research, cardiac arrest (CA) and complications resulting from hypoxic organ injury, remains one of the most significant challenges faced by physicians, knowing that the vast majority of patients with CA have an unfavourable prognosis with a higher chance of death and severe neurological disabilities [ 1 , 2 , 3 ]. In the last few years, efforts have been focused on the best way to detect those patients who have a chance to survive and to recover. In an attempt to identify patients who survived after resuscitated CA

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Theodora Benedek and Mariann Gyöngyösi

References 1. Kern KB. Optimal Treatment of Patients Surviving Out-of- Hospital Cardiac Arrest. JACC Cardiovasc Interv. 2012;5:597-605. 2. Steg G, James SK, Atar D, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology. Eur Heart J. 2012;33:2569-619. 3. Bernard SA, Gray TW, Buist MD, et al. Treatment of comatose survivors of

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Bărcan Andreea, Rat Nora and Orzan Marius

References 1. Schwartz BG, Kloner RA, Thomas JL, et al - Therapeutic hypothermia for acute myocardial infarction and cardiac arrest. Am J Cardiol. 2012 Aug 1;110(3):461-6. 2. Luscombe Mark, Andrzejowsk John - Clinical applications of induced hypothermia. Contin Educ Anaesth Crit Care Pain, 2006, 6(1):23-27, doi: 10.1093/bjaceaccp/mki0. 3. Katz LM, Frank JE, Glickma1. n LT, Jr GM, Lambdrt BH, Gordon CJ. Effect of a Pharmacologically Induced Decrease in Core Temperature in Rats Resuscitated from Cardiac Arrest

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Jarosław Buczyński, Michał Spychalski, Agnieszka Ławska-Wierzchniewska and Adam Dziki

for aminosalicylates in the chemoprevention of colorectal cancer in patients with inflammatory bowel disease. Aliment Pharmacol Ther 2003 Sep; 18 Suppl 2: 15-21. Isao Okayasu, Kiyomi Hana, Tsutomu Yoshida et al.: Significant Increase of Colonic Mutated Crypts in Ulcerative Colitis Correlatively with Duration of Illness. Cancer Res 2002 April 15; 62: 2236-38. Reinacher-Schick A., Schoeneck A., Graeven U et al.: Mesalazine causes a mitotic arrest and induces caspase-dependent apoptosis in colon carcinoma cells