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IA Nechifor-Boila, H Suciu, Loghin Andrada, Borda Angela, A Maier, Martha Orsolya and C Chibelean

arrest. BJU Int, 2006;98:289-297. 15. Pouliot F, Shuch B, Larochelle JC, Pantuck A, Belldegrun AS. Contemporary management of renal tumors with venous tumor thrombus. J Urol, 2010;184:833-841.

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Evelin Szabó, Diana Opincariu, Zsolt Parajkó, Noémi Mitra, Theodora Benedek and Imre Benedek

, Agewall S, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J . 2018;39:119-177. 5. Khera S, Kolte D, Gupta T, et al. Temporal Trends and Sex Differences in Revascularization and Outcomes of ST-Segment Elevation Myocardial Infarction in Younger Adults in the United States. J Am Coll Cardiol . 2015;66:1961-1972. 6. Atwood C, Eisenberg MS, Herlitz J, Rea TD. Incidence of EMS-treated out-of-hospital cardiac arrest in Europe. Resuscitation . 2005;67:75-80. 7. Dumas F

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Jasna Jevdjic, Filip Zunic and Bojan Milosevic

References 1. Atwood C, Eisenberg MS, Herlitz J, Rea TD. Incidence of EMS-treated out-of-hospital cardiac arrest in Europe. Resuscitation 2005; 67:75-80. 2. Nurnberger A, Sterz F, Malzer R, et al. Out of hospital cardiac arrest in Vienna: Incidence and outcome. Resustitation 2013; 84:42-47. 3. Adrie C, Adib-Conquy M, Laurent I et al. Successful cardiopulmonary resuscitation after cardiac arrest as a “sepsis-like” syndrome. Circulation 2002;106:562-8. 4. Nolan JP, Soar J, Cariou A, Cronberg T

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Ana Radovanovic

Altern Med 2013;13: 212. 65. Aziz AFA, Iqbal M. Antioxidant activity and phytochemical composition of Cynometra cauliflora. J Exp Integr Med 2013; 3(4): 337-41. 66. Kretschmer N, Rinner B, Deutsch AJ, et al. Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. J Nat Prod 2012;75(5): 865-9. 67. Seshadri P, Rajaram A, Rajaram R. Plumbagin and juglone induce caspase-3-dependent apoptosis involving the mitochondria through ROS generation in human peripheral blood lymphocytes. Free Radic Biol Med 2011; 51

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M. Perian, M. Mărginean, D. Dobreanu and Alina Scridon

;38:745-749. 7. Minasian SM, Galagudza MM, Dmitriev YV, Kurapeev DI, Vlasov TD. Myocardial protection against global ischemia with Krebs-Henseleit bufferbased cardioplegic solution. J Cardiothorac Surg. 2013;8:60. 8. Nakamura Y, Taremoto N, Kuroda H, Ohgi S. The advantages of normocalcemic continuous warm cardioplegia over low calcemic cardioplegia in myocardial protection. Surg Today. 1999;29:884-889. 9. Tevaearai HT, Eckhart AD, Shotwell KF, Wilson K, Koch WJ. Ventricular dysfunction after cardioplegic arrest is improved after myocardial gene

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Radica Živković Zarić, Marijana Stanojević Pirković and Nedim Hamzagić

cycle checkpoint signaling: Cell cycle arrest versus apoptosis. Toxicology. 2002;181:475-81. 23. Luo Z, Yu L, Yang F, Zhao Z, Yu B, Lai H, Wong KH, Ngai SM, Zheng W, Chen T. Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase. Metallomics. 2014;6(8):1480-90. 24. Thota S, Rodrigues DA, Crans DC, Barreiro EJ. Ru (II) compounds: next-generation anticancer metallotherapeutics?. J Med Chem. 2018;61(14):5805-21. 25. Zheng K, Wu Q, Wang C, Tan W, Mei W. Ruthenium(II) Complexes as Potential

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Mojtaba Rad and Mostafa Rad

weight of rescuer and quality of chest compression during cardiopulmonary resuscitation. J PhysiolAnthropol 2014; 24;33:16. doi: 10.1186/1880-6805-33-16. https://doi.org/10.1186/1880-6805-33-16 4. Williams B, Boyle M, Gutwirth H. Rescuer Fatigue in Cardiopulmonary Resuscitation: A Review of the Literature. Australas JParamed 2012;7(4):4. 5. Abella BS, Alvarado JP, Myklebust H, Edelson DP, Barry A, O'Hearn N, et al. Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. Jama 2005;293(3):305-10. https://doi.org/10.1001/jama.293

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Blagovest Pehlivanov and Maria Orbetzova

;77:141-6. Pigny P, Merlen E, Robert Y, et al. Elevated serum level of anti-Müllerian hormone in patients with polycystic ovary syndrome: relationship to the ovarian follicle excess and to the follicular arrest. J Clin Endocrinol Metab 2003;88:5957-62. Laven JSE, Mulders A, Visser JA, et al. Anti-Müllerian hormone serum concentrations in normoovulatory and anovulatory women of reproductive age. J Clin Endocrinol Metab 2004; 89: 318-23. Pellatt L, Hanna L, Brincat M, et al. Granulosa cell production of anti-Müllerian hormone is

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Dejan Petrović, Marina Deljanin Ilić, Bojan Ilić, Sanja Stojanović, Milovan Stojanović and Dejan Simonović

Summary

Asystole is a rare primary manifestation in the development of sudden cardiac death (SCD), and survival during cardiac arrest as the consequence of asystole is extremely low. The aim of our paper is to illustrate successful cardiopulmonary resuscitation (CPR) in patients with acute myocardial infarction (AMI) and rare and severe form of cardiac arrest - asystole. A very short time between cardiac arrest in acute myocardial infarction, which was manifested by asystole, and the adequate CPR measures that have been taken are of great importance for the survival of our patient.

After successful reanimation, the diagnosis of anterior wall AMI with ST segment elevation was established. The right therapeutic strategy is certainly the early primary percutaneous coronary intervention (PPCI). In less than two hours, after recording the “flatline” and successful reanimation, the patient was in the catheterization laboratory, where a successful PPCI of LAD was performed, after emergency coronary angiography. In the further treatment course of the patient, the majority of risk factors were corrected, except for smoking, which may be the reason for newly discovered lung tumor disease. Early recognition and properly applied treatment of CPR can produce higher rates of survival.

Open access

Sabah Boudjemaa, Valérie Meau-Petit, Fazia Hallalel, Aurore Coulomb and Jill Lipsett

Abstract

Idiopathic pulmonary arterial hypertension is a rare disease in children. We report a case of a 2-year old boy admitted to the intensive care unit of our hospital for severe dyspnea and epistaxis. Laboratory investigations showed hemolytic anemia with schizocytes and severe thrombocytopenia. Cardiac investigations diagnosed supra-systemic pulmonary arterial hypertension, which was refractory to maximal medical treatment. On evolution, he had several cardiac arrests and finally died 8 days after admission. Autopsy was performed and showed typical lesions of idiopathic pulmonary hypertensive arteriopathy characterized by plexiform lesions of the interlobular arteries containing numerous disseminated intravascular microthrombi. The rest of the family was screened, DNA was stored, and genetic study of BMPR2 was planned.