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Nephrin and Podocalyxin - New Podocyte Proteins for Early Detection of Secondary Nephropathies

domainmediated interaction of rabbit podocalyxin and Na+/H+ exchange regulatory factor-2. Am J Physiol Renal Physiol 2002; 282(6): F1129-F1139. 17. Doyonnas DB Kershaw, Duhme C, et al. Anuria, omphalocele, and perinatal lethality in mice lacking the CD34- related protein podocalyxin. J Exp Med 2001; 194(1): 13-27. 18. Takeda T, Go WY, Orlando RA, et al. Expression of podocalyxin inhibits cell-cell adhesion and modifies junctional properties in Madin-Darby canine kidney cells. Mol Biol Cell 2000; (11): 3219-3232. 19. Pollak MR

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Podocytes and Proteinuric Kidney Disease

(Bethesda) 2009; 24: 88-96. 13. Abbate M Zoja C, Morigi M, et al. Transforming growth factor-beta1 is upregulated by podocytes in response to excess intraglomerular passage of proteins. A central pathway in progressive glomerulosclerosis. Am J Path 2002; 161: 2179. 14. Benzing T. Signaling at the slit diaphragm. J Am Soc Nephrol 2004; 15: 1382-1391. 15. Lasagni L, Romagnani P. Glomerular epithelial stem cells, the good, the bad, and the ugly. J Am Soc Nephrol 2010; 21: 1612-1619. 16. Welsh GI, Saleem MA. The podocyte cytoskeleton-key to a functioning

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