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Diagnosis and management of complications of chronic lymphocytic leukemia/small lymphocytic lymphoma

therapies resulting in longer survival. Immune dysfunction effecting both the adaptive and innate immune responses occurs early in the course of CLL and high-count monoclonal B-cell lymphocytosis (MBL) [ 6 , 7 , 8 ]. The mechanism by which CLL induces immune dysfunction is poorly understood. T cell dysfunction in CLL is characterized by abnormal CD4:CD8 effector ratios, skewed helper T cell profiles (e.g., increased Th2:Th1), impaired immune synapse formation, and reduced proliferative and cytotoxic activities characteristic of T cell exhaustion [ 8 , 9 , 10 , 11

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Faster Evaluation of Induced Floral Sterilit

References AHN, J. H., D. MILLER, V. J. WINTER, M. J. BANFIELD, J. H. LEE, S. Y. YOO, S. R. HENZ, R. L. BRADY and D. WEIGEL (2006): A divergent external loop confers antagonistic activity on floral regulators FT and TFL1. EMBO J. 25: 605-14. BEALS, T. P. and R. B. GOLDBERG (1997): A novel cell ablation strategy blocks tobacco anther dehiscence. Plant Cell 9: 1527-45. BÖHLENIUS, H., T. HUANG, L. CHARBONNEL-CAMPAA, A. M. BRUNNER, S. JANSSON, S. H. STRAUSS and O. NILSSON (2006): CO/FT regulatory module controls

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Selection and validation of reference genes for real-time qRT-PCR normalization in different tissues of Eucalyptus tereticornis

primary cell wall synthesis in Bambusa oldhamii. Phytochemistry 71: 1270-1279. CHEZHIAN, P., R. YASODHA and M. GHOSH (2010): Genetic diversity analysis in a seed orchard of Eucalyptus tereticornis. New Forest 40(1): 85-99. CZECHOWSKI, T., M. STITT, T. ALTMAN, M. K. UDVARDI and W. R. SCHEIBLE (2005): Genome-wide identification and testing of superior reference genes for transcript normalization in Arabidopsis. Plant Physiol 139(1): 5-17. DAY, M. E., M. S. GREENWOOD and C. DIAZ-SALA (2002): Age- and size-related trends in

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Co-expression network of secondary cell wall biogenesis genes in Eucalyptus tereticornis

relevant characteristics of Eucalyptus species. BMC Genomics 14: 201. 201 Shannon P, A Markiel, O Ozier, NS Baliga, JT Wang, D Ramage, N Amin, B Schwikowski and T Ideker (2003) Cytoscape, a software environment for inte­grated models of biomolecular interaction networks. Genome Research 13: 2498-2504. Shi R, JP Wang, Y-C Lin, Q Li, Y-H Sun, H Chen, RR Sederoff and VL Chiang (2017) Tissue and cell-type co-expression networks of transcription factors and wood component

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Characterization of genes expressed in Casuarina equisetifolia in response to elicitation by cell wall components of Trichosporium vesiculosum

References ADOMAS, A., G. HELLER, G. LI, A. OLSON, T. M. CHU, J. OSBORNE, D. CRAIG, L. VAN ZYL, R. WOLFINGER, R. SEDEROFF, R. A. DEAN, J. STENLID, R. FINLAY and F. O. ASIEGBU (2007): Transcript profiling of a conifer pathosystem: response of Pinus sylvestris root tissues to pathogen (Heterobasidion annosum) invasion. Tree Physiol 27: 1441-1458. ANDJELKOVIC, V. and R. THOMPSON (2006): Changes in gene expression in maize kernel in response to water and salt stress. Plant Cell Rep 25: 71-79. ASAHI, T., Y. HONDA and

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Microarray Analysis of Gene Expression in Triploid Black Poplar

. YOKOTA, F. NAGY and M. SZEKERES (2002): Regulation of transcript levels of the Arabidopsis cytochrome p450 genes involved in brassinosteroid biosynthesis. Plant Physiol 130: 504-513. BAO, F., J. SHEN, S. R. BRADY, G. K. MUDAY, T. ASAMI and Z. YANG (2004): Brassinosteroids interact with auxin to promote lateral root development in Arabidopsis. Plant Physiol 134: 1624-1631. BLANC, G. and K. H. WOLFE (2004): Widespread paleopolyploidy in model plant species inferred from age distributions of duplicate genes. Plant Cell 16: 1667

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Physiological and Protein Responses to Drought in Four Pine Seedlings

-1005. SPREITZER, R. J. and M. E. SALVUCCI (2002):. Rubisco: structure, regulatory interactions, and possibilities for a better enzyme. Annual Review of Plant Biology 53: 449-475. TAKEZAWA, D. (1999): Elicitor- and A23187-induced expression of WCK-1, a gene encoding mitogen-activated protein kinase in wheat. Plant Molecular Biology 40: 921-933. TYREE, M. T. and U. T. HAMMEL (1972): The measurement of the turgor pressure and the water relations of plants by the pressure bomb technique. Journal of Experimental Botany 23: 267

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Immunoterapia z użyciem przeciwciał monoklonalnych ukierunkowanych na szlak PD-1/PD-L1 w chorobach nowotworowych
Monoclonal antibodies against PD-1/PD-L1 pathway

, Thomson AW. Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells. J Immunol. 2006;176(5):2808–16. 10.4049/jimmunol.176.5.2808 Raimondi G Shufesky WJ Tokita D Morelli AE Thomson AW Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells J Immunol 2006 176 5 2808 – 16 [19] Francisco LM, Salinas VH, Brown KE, Vanguri VK, Freeman GJ, Kuchroo VK, et al. PD-L1 regulates the development

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Selected factors influencing angiogenesis and hematopoietic niche

decreased expression of major histocompatibility complex (MHC) II antigens, which in turn impairs the function of T-lymphocytes [ 20 ]. This process is associated with decreased activity of NK-κB signaling pathway [ 8 ]. VEGF significantly regulates proliferation and migration of EC. By recruiting HSC and endothelial progenitor cells VEGF regulates microvessels development in the bone marrow niche and fundamentally affects hematopoiesis [ 15 , 21 ]. ANGPT1 and ANGPT2 Apart from VEGF, angiopoietin 1 (ANGPT1) and angiopoietin 2 (ANGPT2), both binding to receptor

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Prognostic value of soluble angiotensin II receptor 1 and soluble angiotensin converting enzyme (CD 143) in patients with acute leukemia

accumulation of blast cells in the bone marrow and peripheral blood [ 12 ]. Acute lymphoblastic leukemia (ALL) is a malignant disease characterized by the accumulation of lymphoblasts and it may be B or T lineages and the first attempt at classifying ALL was the French-American-British (FAB) morphological criteria that divided ALL into 3 subtypes (L1, L2 and L3) based on cell size, cytoplasm, nucleoli, vacuolation and basophilia. In 1997, the World Health Organization proposed a composite classification in an attempt to account for morphology and cytogenetic profile of the

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