Mesenchymal stem cell (MSC) is a multipotential nonhaematopoietic progenitor cell that is able to differentiate into various cell lineages. MSC can differentiate into osteoblasts, chondrocytes, myocytes, adipose tissues, endothelial cells, neuron-like cells, cardiomyocytes and hepatocytes. MSCs lack expression of co-stimulatory molecules, are capable of escaping from alloantigen recognition and, hence, have low immunogenicity. This is why MSCs are candidate cells to prevent rejection in transplant therapy and can be a potential treatment
Mohammed Nader Shalaby, Mohammed Saad, Samy Akar, Mubarak Abdelreda Ali Reda and Ahmed Shalgham
Amany A, Mohamed S. Effect of concurrent training on CD 34+ /CD 45+ stem cells, VO 2max , certain physical variables and record level of 1500 m running 52 Ischper - SD World congresses, Cairo, Egypt; 2011
Asahara T, Takahashi T, Masuda H, Kalka C, Chen D, Iwaguro H, Inai Y, Silver M, Isner JM. VEGF contributes to postnatal neovascularization by mobilizing bone marrow derived endothelial progenitor cells. EMBO J , 1999; 18: 3964-3972
Barrett K, Barman S, Boitano S. Ganong Review of Medical
Piotr Kaczka, Małgorzata Magdalena Michalczyk, Rafał Jastrząb, Mateusz Gawelczyk and Katarzyna Kubicka
insulin-like growth factor-1 (IGF-1) gene (Gerlinger- Romero et al., 2011). Besides, in vivo studies point to the fact that HMB improves the proliferation of muscle stem cells in fast twitch fibers ( Asadi et al., 2017 ). Enhanced satellite cell proliferation should increase muscle hypertrophic changes and functional changes ( Alway et al., 2013 ).
Several possible mechanisms of HMB action on the human body are presented in Scheme 2 .
Possible mechanisms of HMB action in the human body
The effect of HMB on the mTOR kinase pathway
Jarosław Muracki, Martyna Kumorek, Aleksandra Kisilewicz, Beata Pożarowszczyk, Dennis Boye Larsen, Adam Kawczyński and Shellie Boudreau
Participants could choose from three colors to express MP, JP, and IP. Blue, grey, and red were used to represent MP, JP, and IP, respectively. Participants were asked to qualify pain as MP when it was localized only within the muscle structure and it was not caused by direct impact, although technically that could also be a source of MP. Reporting of JP referred to pain stemming from the joint area and not directly related to an impact, yet it was considered as a result of external or internal loads during joint movement. Participants were also informed that IP should be
Szymon Czech, Jacek Hermanson, Piotr Rodak, Tomasz Stołtny, Łukasz Rodak, Sławomir Kasperczyk, Bogdan Koczy and Michał Mielnik
1st Department of Trauma and Orthopaedic Surgery who were specialists in the field of trauma and orthopaedics. The R3 acetabular system with Verilast articulation and Nanos hip stem (Smith&Nephew) were used in all patients.
All patients who fulfilled the inclusion criteria were invited for a medical appointment to the hospital outpatient clinic. Among 137 patients who fulfilled criteria, 106 subjects accepted the invitation. During the appointment, the patients underwent routine physical examinations following the Harris Hip Score protocol, responded to the UCLA
Andrzej Klusiewicz, Lech Borkowski, Dariusz Sitkowski, Krystyna Burkhard-Jagodzińska, Beata Szczepańska and Maria Ładyga
The aim of the study was to evaluate the usefulness of indirect methods of assessment of VO2max for estimation of physical capacity of trained male and female rowers during a training cycle. A group of 8 female and 14 male rowers performed the maximal intensity test simulating the regatta distance (a 2 km test) and a submaximal incremental exercise test on a rowing ergometer. The suitability of the indirect methods of predicting VO2max during the training cycle was evaluated by performing the tests twice: in females at an interval of five months and in males at an interval of seven months. To indirectly estimate VO2max, regression formulas obtained for the linear relationship between the examined effort indices were utilized based on 1) mean power obtained in the 2 km test, and 2) submaximal exercises after the estimation of PWC170. Although the suitability of the two indirect methods of assessment of VO2max was statisticaly confirmed, their usefulness for estimation of changes in physical fitness of trained rowers during the training cycle was rather low. Such an opinion stems from the fact that the total error of these methods (range between 4.2-7.7% in female and 5.1-7.4% in male rowers) was higher than the real differences in VO2max values determined in direct measurements (between the first and the second examination maximal oxygen uptake rose by 3.0% in female rowers and decreased by 4.3% in male rowers).
Foul Play in Sport as a Phenomenon Inconsistent with the Rules, yet Acceptable and Desirable
Author considers assumptions related to foul play in sport as a phenomenon, that affect the body, psyche, or relationships - various social involvements, conditionings, and determinants of those involved with that particular form of athletic activity. This includes fouls committed on and off the field, as well as those not even related to a particular game. Our considerations include fouls of a verbal or acoustic nature; fouls in the form of printed materials; those in the form of visual commentary in films, TV shows, Internet appearances, whether in feature films, dramatized documentaries, documentaries or reports presented in a different publications, festivals, exhibitions, during which co-participants, adversaries or competitors make comments on past or future events during or beyond the competition.
Fouls in sport, particularly those committed by athletes during competition, will always be inconsistent with the accepted rules of the game, that is, with the official regulations. Fouls will also always influence - in more or less annoying, depressing, painful or even tragic ways - the fate and the health of athletes.
No logical - conditional, cause and effect - connection exists between a foul and the rules. Neither the need for nor praise of foul play can stem from the regulations. Yet people directly associated with the sport tolerate it because there is a widespread, quiet acquiescence of such play. Foul play is strongly opposed by supporters of the fair play principle, by those who do not regard sports competition as a phenomenon that can be considered independently beyond moral good and evil.
Foul play is seen also as a desirable phenomenon, when inter alia, regardless of the various penalties imposed on players and team, it helps - in the final balance of losses and benefits - to achieve the planned success. Moreover, it is worth adding that, for instance, the so-called "good foul" in basketball enables one to stop the game clock, the so-called pure-play time of the referee. This creates the possibility of obtaining at least one more point (for a possible 3-point shot from a distance) than the team that executes its two one-point penalty shots granted for the offense (that is, "good foul").
Foul play may also enhance the course of the sports spectacle, and encourage spectators to cheer more frequently. This is particularly important when professional athletic contests are treated as a form of business. The dramatization of foul play as a creation of "game" within a game can also be an additional attraction of the competition; foul play might be used as sophisticated and spectacular trickery, that dismays and hurts in its pragmatic-aesthetic construction, both the referee and the opponent.
Foul play in sports has so many forms and will probably never lose its popular and sometimes spectacular character. Knowing that, everything should be done to protect players from bothersome health, interpersonal, and cultural disablements resulting from foul play.
Teresa Zwierko, Wieslaw Osinski, Wojciech Lubinski, Damian Czepita and Beata Florkiewicz
Allison T., Wood C. C., Goff W. R. Brain stem auditory, pattern-reversal visual, and short-latency somatosensory evoked potentials: latencies in relation to age, sex, and brain and body size. Electroencephalogr Clin Neurophysiol , 1983. 55: 619-36
Ando S., Kida N., Oda S. Central and peripheral visual reaction time of soccer players and nonathletes. Percept Mot Skills , 2001. 92 (3): 786-794
Bhanot J. L., Sindu L. S. Comparative study of reaction time in Indian
hematological malignancies and autoimmune diseases. [ 16 - 18 ] CD20 is a B cell-specific differentiation antigen that is expressed on pre-B and mature B cells, which is lost upon differentiation into plasma cells. Rituxima breacts specifically with the CD20 antigen expressed on B-cells and leads to rapid depletionof a majority of these CD20-expressing B cells in the peripheral blood via the complement-mediated and antibody-dependent cell-mediated cytotoxicity. Stem cells, pro-B-cells and plasma cells that do not express CD20 are spared, which allows for B cell recovery after
Leesa Pearce, Carl Woods, Wade Sinclair and Anthony Leicht
Not dissimilar to other football codes, rugby league (RL) can be characterised as an intermittent team sport that requires players to combine high intensity running efforts with periods of lower-intensity activity ( Gabbett et al., 2012 ). This characterisation stems from the wealth of literature that has profiled the movement demands of players amongst differing levels of competition ( Gabbett, 2013 , 2012 ; Johnston et al., 2014 ; Kempton et al., 2014 ). However, the movement profiles of RL match officials appear to be slightly more