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Ewelina Wawryk-Gawda and Beata Wojcik

References 1. Ahn S.Y., Chang Y.S., Park W.S.: Mesenchymal stem cells transplantation for neuroprotection in preterm infants with severe intraventricular hemorrhage. Korean J Pediatr 57(6):251-6,2014. doi: 10.3345/kjp.2014.57.6.251. 2. Bajek A., Olkowska J., Drewa T.: Mesenchymal stem cells as a therapeutic tool in tissue and organ regeneration. Postepy Hig Med Dosw 24;65:124-32,2011. 3. Ball L.M., et al.: Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid

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Zlate Stojanoski, Aleksandra Pivkova, Sonja Genadieva-Stavrik, Lidija Cevreska, Milena Petrovska and Borche Georgievski

. Chanock SJ, Walsh TJ. Invasive aspergillosis in bone marrow recipients. Bone Marrow Transplant. 1996;18 Suppl 3:S15-20. PMID: 8971401 Marr KA. Epidemiology and outcome of mold infections in hematopoietic stem cell transplant recipients. Clin Infect Dis. 2002;34:909-917. doi:10.1086/339202 PMID:11880955 Viscoli C, Girmenia C, Marinus A, Collette L, Martino P, Vandercam B, Doyen C, Lebeau B, Spence D, Krcmery V, De Pauw B, Meunier F. Candidemia in cancer patients: a prospective, multicenter surveillance study by the

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Supreecha Chattong, Ruttachuk Rungsiwiwut, Wittaya Yindeedej, Amornpun Sereemaspun, Kamthorn Pruksananonda, Pramuan Virutamasen, Anant Setpakdee and Krissanapong Manotham

References 1. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998; 282:1145-7. 2. Amit M, Carpenter MK, Inokuma MS, Chiu CP, Harris CP, Waknitz MA, et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev Biol. 2000; 2:271-8. 3. Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, et al

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András Mester, Diana Opincariu, Imre Benedek and István Benedek

REFERENCES 1. Boulton AJ, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J. The global burden of diabetic foot disease. Lancet . 2005;366:1719-1724. 2. Rando TA. Stem cells, ageing and the quest for immortality. Nature . 2006;441:1080-1086. 3. Sen CK, Gordillo GM, Roy S, et al. Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen . 2009;17:763-771. 4. Crovetti G, Martinelli G, Issi M, et al. Platelet gel for healing cutaneous chronic wounds. Transfus Apher Sci . 2004;30:145-151. 5

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Enikő Kakucs, I Benedek, Erzsébet Benedek, Judit Beáta Köpeczi, Aliz Tunyogi and Monica Istrati

References 1. Apperley J, Carreras E, Gluckman E, Masszi T. The EBMT Handbook Haematopoietic Stem Cell Transplantation. 6th Revised Edition. 2012:317-326 2. Tsimberidou AM, Stavroyianni N, Viniou N. Comparison of allogeneic stem cell transplantation, high-dose cytarabine, and autologous peripheral stem cell transplantation as postremission treatment in patients with de novo acute myelogenous leukemia. Cancer. 2003;97(7):1721-1731. 3. Büchner T, Berdel WE, Schoch C, et al. Double induction containing

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Adam A. Mieloch and Wiktoria M. Suchorska

References 1. Jones DL, Wagers AJ. No place like home: anatomy and function of the stem cell niche. Nat Rev Mol Cell Biol 2008; 9: 11-21. 2. Tropepe V, Turksen K. The ontogeny of somatic stem cells. Stem Cell Rev 2012; 8: 548-50. 3. Moore K A, Lemischka IR. Stem cells and their niches. Science 2006; 311: 1880-5. 4. Turksen K. Adult stem cells and cardiac regeneration. Stem Cell Rev 2013; 9: 537-40. 5. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by

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Maha El Fattah, Gang Ding, Fulan Wei, Chunmei Zhang, Eman Ezz and Songlin Wang

References Bartold PM, McCulloch CAG, Narayanan AS, Pitaru S. Tissue-engineering:a new paradigm for periodontal regeneration based on molecular and cell biology. Periodontol 2000. 2000;22:169-189. Anderson D, Gage F, Weissman I. Can stem cells cross lineage boundries? Nat Med. 2001;7:393-395. Elter JR, Offenbacher S, Toole JF, Beck JD. Relationship of periodontal disease and edetulism to stroke. J Dent Res. 2003;82:998-1001. Ivanovski S, Gronths S, Shi S

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Zlate Stojanoski, Anzelika Karadzova-Stojanoska, Aleksandra Pivkova-Veljanovska, Sonja Genadieva-Stavrik, Lazar Cadievski, Martin Ivanovski, Oliver Karanfilski, Lidija Cevreska and Borce Georgievski

References 1. Tyndall A, and Gratwohl A. Blood and marrow stem cell transplants in auto-immune disease: a consensus report written on behalf of the European League against Rheumatism (EULAR) and the European Group for Blood and marrow transplantation (EBMT). Bone Marrow Transplantation 1997; 19: 643-645. 2. van Laar JM, Farge D, Sont JK, et al . EBMT/EULAR Scleroderma Study Group.: Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial. JAMA

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István Benedek, Judit-Beáta Köpeczi, Enikő Kakucs, Szende Jakab, István Benedek and Erzsébet Lázár

References 1. Vonk AL, de Windt TS, Slaper-Cortenbach ICM, Saris DBF. Autologous, allogeneic, induced pluripotent stem cell or a combination stem cell therapy. Stem Cell Res Ther. 2015;6:94. 2. Kimbrel EA, Kouris NA, Yavanian GJ, et al. Mesenchymal stem cell population derived from human pluripotent stem cells displays potent immunomodulatory and therapeutic properties. Stem Cells Dev. 2014;23:1611-1624. 3. Isolex 300i Trening Manual, Version 2, Nexel Therapeutics Inc. USA, 2001, Section 2 4. McDonald-Hyman C, Turka LA, Blazar BR. Advances

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Winnie Wan-Yin Yeung and Chak-Sing Lau

1 Introduction Mesenchymal stem cell (MSC) is a multipotential nonhaematopoietic progenitor cell that is able to differentiate into various cell lineages. MSC can differentiate into osteoblasts, chondrocytes, myocytes, adipose tissues, endothelial cells, neuron-like cells, cardiomyocytes and hepatocytes. MSCs lack expression of co-stimulatory molecules, are capable of escaping from alloantigen recognition and, hence, have low immunogenicity. This is why MSCs are candidate cells to prevent rejection in transplant therapy and can be a potential treatment