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Supreecha Chattong, Ruttachuk Rungsiwiwut, Wittaya Yindeedej, Amornpun Sereemaspun, Kamthorn Pruksananonda, Pramuan Virutamasen, Anant Setpakdee and Krissanapong Manotham

References 1. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998; 282:1145-7. 2. Amit M, Carpenter MK, Inokuma MS, Chiu CP, Harris CP, Waknitz MA, et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev Biol. 2000; 2:271-8. 3. Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, et al

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Sittisak Honsawek and Wannee Unwerawattana

expression in periodontal health and disease. Crit Rev Oral Biol Med. 1998; 9:248-66. 5. Reber L, Da Silva CA, Frossard N. Stem cell factor and its receptor c-Kit as targets for inflammatory diseases. Eur J Pharmacol. 2006; 533:327-40. 6. Zsebo KM , Williams DA , Geissler EN, Broudy VC, Martin FH, Atkins HL, et al. Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell. 1990; 63:213-24. 7. Yarden Y , Kuang WJ , Yang-Feng T, Coussens L, Munemitsus S, Dull TJ, et

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Thakoon Thitiset, Supranee Buranapraditkul, Siriporn Damrongsakkul and Sittisak Honsawek

References 1. Stute N, Holtz K, Bubenheim M, Lange C, Blake F, Zander AR. Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use. Exp Hematol. 2004; 32:1212-25. 2. Deans RJ, Moseley AB. Mesenchymal stem cells: Biology and potential clinical uses. Exp Hematol. 2000; 28:875-84. 3. Devine SM. Mesenchymal stem cells: Will they have a role in the clinic? J Cell Biochem. 2002; 85:73-9. 4. Salehinejad P, Alitheen NB, Ali AM, Omar AR, Mohit M, Janzamin E, et al

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Shengyun Huang, Shanshan Jia, Guijun Liu, Dong Fang and Dongsheng Zhang

References 1. Feldmann RE Jr, Bieback K, Maurer MH, Kalenka A, Burgers HF, Gross B, et al. Stem cell proteomes: a profile of human mesenchymal stem cells derived from umbilical cord blood. Electrophoresis. 2005; 26: 2749-58. 2. Chen TL, Shen WJ, Kraemer FB. Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures. J Cell Biochem. 2001; 2:187-99. 3. Allan EH, Ho PW, Umezawa A, Hata J, Makishima F, Gillespie MT, et al. Differentiation potential of a

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Yong Guo, Xizheng Zhang, Chunqiu Zhang, Ruixin Li, Qiangcheng Zeng, Chun Guo and Yanjun Zhang

References 1. Tholpady SS, Katz AJ, Ogle RC. Mesenchymal stem cells from rat visceral fat exhibit multipotential differentiation in vitro. Anat Rec. 2003; 272A:398-402. 2. De Ugarte DA, Morizono K, Elbarbary A, Alfonso Z, Zuk PA, Zhu M, et al. Comparison of multi-lineage cells from human adipose tissue and bone marrow. Cells Tissues Organs. 2003; 174:101-9. 3. Gaustad KG, Boquest AC, Anderson BE, Gerdes AM, Collas P. Differentiation of human adipose tissue stem cells using extracts of rat cardiomyocytes. Biochem

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Jafar Ai, Ebrahim Azizi, Azam Shamsian, Akram Eslami, Ahad Khoshzaban, Somayeh Ebrahimi-Barough, Armin Ai and Aliakbar Alizadeh

References 1. Marolt D, Knezevic M, Novakovic GV. Bone tissue engineering with human stem cells. Stem Cell Res Ther. 2010; 1:10. 2. Schneider RK, Puellen A, Kramann R, Raupach K, Bornemann J, Knuechel R, et al. The osteogenic differentiation of adult bone marrow and perinatal umbilical mesenchymal stem cells and matrix remodelling in three-dimensional collagen scaffolds. Biomaterials. 2010; 31:467-80. 3. Conrad C, Huss R. Adult stem cell lines in regenerative medicine and reconstructive surgery. J Surg Res. 2005

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Mathana Amaris Fiona Sivaraman and Siti Nurani Mohd Noor

References 1. Thomson JA, Itskovitz-Eldor J, Shapiro SS. Embryonic stem cell lines derived from human blastocysts. Science. 1998; 282:1145-7. 2. McLaren A. Ethical and social considerations of stem cell research. Nature. 2001; 414:129-31. 3. Braverman A, Steinbock B, Wilder B, Batzer F, Robertson J, Francis L. Donating spare embryos for stem cell research. Fertil Steril. 2009; 91:667-70. 4. MOH. Malaysian guidelines for stem cell research and therapy. 2009; http

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Nunthawan Nowwarote, Chenphop Sawangmake, Prasit Pavasant and Thanaphum Osathanon

Basic fibroblast growth factor (bFGF) or fibroblast growth factor 2 (FGF2), a member of the fibroblast growth factor family, regulates cell growth, differentiation, migration, and survival during development and regeneration [ 1 - 3 ]. bFGF has various roles in stem cell biology including the maintenance of stemness and control of differentiation [ 4 , 5 ]. To maintain stemness, bFGF regulates the self-renewing ability of several cell types [ 6 ]. bFGF signaling plays a crucial role in the self-renewal capacity of human embryonic stem cells (ES) and human

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Apitsada Khlongkhlaeo, Richard L. Carter, Rangsun Parnpai and Anthony W.S. Chan

Cell therapies and stem cell applications are widespread topics in biomedicine. Embryonic stem cells (ESCs) are self-renewing pluripotent cells, which can differentiate into various cell and tissue types of all 3 germ lineages. Their high rate of proliferation and pluripotent characteristics make them one of the best cell sources for modeling diseases in vitro and the development of cell therapies for diseases such as Parkinson’s and Huntington’s. Neural stem cells can be isolated and expanded from the subventricular zone and the subgranular zone of the

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Vicky Hsin-Ju Lu, James Gollogly, Soryoun Soeung and Thorn Pok

TT, Lavker RM. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell. 1989; 57: 201-9. 9. Stoiber J, Muss WH, Pohla-Gubo G, Ruckhofer J, Grabner G. Histopathology of human corneas after amniotic membrane and limbal stem cell transplantation for severe chemical burn. Cornea. 2002; 21:482-9. 10. Ucakhan OO, Koklu G, Firat E. Nonpreserved human amniotic membrane transplantation in acute and chronic chemical eye injuries. Cornea. 2002; 21