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R eferences 1. Băncescu O, Ionescu-Tîrgovişte C. Atomic force microscopy. Its potential in diabetes research. Rom J Diabetes Nutr Metab Dis 14(2): 35-41, 2007 2. Nicoară A, Pencea C, Lichiardopol R. Association between diabetes mellitus and chronic hepatitis C virus infection. Rom J Diabetes Nutr Metab Dis 14(3): 15-23, 2007 3. Băncescu O. Stem cell a new cure in diabetes disease. Rom J Diabetes Nutr Metab Dis 15(1): 19-29, 2008 4. Cărăbineanu R. The potential use of glycated hemoglobin for diabetes screening/diagnosis. Rom J

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Mihaela Aldea, Lucian Craeiun, Tiberiu Popescu, Iuliana Nenu and Carmen Crivii

-density lipoprotein cholesterol in nondiabetic, morbidly obese subjects with body mass index greater than 30. Metabolism 50: 856-861, 2001. 4. Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res 69: 7507-7511, 2009. 5. Pawelczyk L, Spaczynski RZ, Banaszewska B, Duleba AJ. Metformin therapy increases insulin-like growth factor binding protein-1 in hyperinsulinemic women with polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol

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Mohammad Reza Panjeshahin, Mohammad Azadbakht and Niattollah Akbari

R eferences 1. Dabaghian FH, Kamalinejad M, Shojaei A, Abdollahi Fard M . Presenting anti-diabetic plants in Iranian traditional medicine. J Diabetes Endocrinol 3: 70-76, 2012. 2. Pulipaka S, Challa SR, Pingili RB . Comparative antidiabetic activity of methanolic extract of Operculina turpethum stem and root against healthy and streptozotocin induced diabetic rats. Int Current Pharm J 1: 272-278, 2012. 3. International Diabetes Federation. IDF Diabetes Atlas, 6th ed. Brussels: International Diabetes Federation, 2013. Accessed at: http

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Simona Georgiana Popa

References 1. Pula G, Mayr U, Evans C, Prokopi M, Vara DS, Yin X, Astroulakis Z, Xiao Q, Hill J, Xu Q, Mayr M. Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures. Circ Res 104: 32-40, 2009. 2. Dotsenko O. Stem/Progenitor cells, atherosclerosis and cardiovascular regeneration. Open Cardiovasc Med J 4: 97-104, 2010. 3. Sieveking DP, Buckle A, Celermajer DS, Ng MK. Strikingly different angiogenic

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Deniz Korkut, Gul Ergor, Gulsah Kaner and Nilgun Seremet Kurklu

. 19. Selvin E, Parrinello CM, Sacks DB. Trends in prevalence and control of diabetes in the United States, 1988-1994 and 1999-2010. Ann Intern Med 160: 517-525, 2014. 20. Stem MS, Blachley TS, Shtein RM. Impact of diagnosing diabetic complications on future hemoglobin A1c levels. J Diabetes Complications 30: 323-328, 2016. 21. Ruta LM, Magliano DJ, Lemesurier R, Taylor HR, Zimmet PZ, Shaw JE. Prevalence of diabetic retinopathy in type 2 diabetes in developing and developed countries. Diabet Med 30: 387-98, 2013. 22

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Hasmar Fajriana, Arta Farmawati and Lily Arsanti Lestari

. International Textbook of Diabetes Mellitus. Fourth Ed. UK: John Wiley; 2015. 5. Nugroho AE . Animal models of diabetes mellitus : pathology and mechanism of some diabetogenics. Biodiversitas, J Biol Divers 7: 378-382, 2006. 6. McPhee SJ, Ganong WF . Patofisiologi Penyakit: Pengantar Menuju Kedokteran Klinis. Bahasa Ind. Jakarta: EGC; 2010. 7. Lekshmi RK, Rajesh R, Mini S . Ethyl acetate fraction of cissus quadrangularis stem ameliorates hyperglycaemia-mediated oxidative stress and suppresses inflammatory response in nicotinamide/streptozotocin induced

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Ramona Maria Ştefan, Cristina Niţă, Anca Crăciun, Adriana Rusu and Nicolae Hâncu

. Available from: http://www.idf.org/sites/default/files/EN_6E_Atlas_Full_0.pdf . 7. Tripathi BK, Srivastava AK. Diabetes mellitus: complications and therapeutics. Med Sci Monit 12: RA130–RA147, 2006. 8. Wu Y, Ding Y, Tanaka Y, Zhang W. Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention. Int J Med Sci 11: 1185–1200, 2014. 9. Zhao Y, Jiang Z, Guo C. New hope for type 2 diabetics: targeting insulin resistance through the immune modulation of stem cells. Autoimmun Rev 11: 137–142, 2011. 10. Mahajan

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Sunarti, Nurliyani, Agatha Swasti Ayuning Tyas, Scolastika Dita Kristian and Prasetyastuti

. 30. Wang X, Bao W, Liu J et al. Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis. Diabetes Care 36: 166-175, 2013. 31. Mahluji S, Ostadrahimi A, Mobasseri M, Attari VE, Payahoo L. Anti-inflammatory effects of Zingiber officinale in type 2 diabetic patients. Adv Pharm Bull 3: 273-276, 2013. 32. Lv SS, Liu G, Wang JP et al. Mesenchymal stem cells transplantation ameliorates glomerular injury in streptozotocin-induced diabetic nephropathy in rats via inhibiting macrophage infiltration. Int

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Inna Krynytska, Mariya Marushchak and Anastasiia Rutska

lymphokine-activated killer cells induce endogenous nitric oxide synthesis and apoptosis in DLD-1 colon cancer cells. Cell Immunol 203(2): 84-94, 2000. 33. Komarevtseva IA, Orlova EA, Tarasova MV et al. Level of nitric oxide in tissues, plasma of blood, mononuclear and mesenchimal stem cells. Ukrainian Journal of Clinical and Laboratory Medicine 4(4): 133-137, 2009. 34. Mazhitova MV, Teplyy DD. Age and sex characteristics of free radical processes and antioxidant protection of the blood plasma of white rats. Natural Sciences 1(30): 79-85, 2010.

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Larysa B. Bondarenko, Ganna M. Shayakhmetova, Anatoliy V. Matvienko and Valentina M. Kovalenko

in diabetic rats. Endocr Res 31: 229-243, 2005. 19. Kim BM, Eichler J, Reiser KM et al. Collagen structure and nonlinear susceptibility: effects of heat, glycation, and enzymatic cleavage on second harmonic signal intensity. Lasers Surg Med 27: 329-335, 2000. 20. Chamberlain JR, Schwarze U, Wang PR et al. Gene targeting in stem cells from individuals with osteogenesis imperfect. Science 303: 1198-1201, 2004. 21. He Z, Feng L, Zhang X et al. Expression of Col1a1, Col1a2 and procollagen I in germ cells of