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Polymorphisms of AZIN1 rs2679757 and TRPM5 rs886277 are Associated with Cirrhosis Risk in Chinese Patients with Chronic Hepatitis B

References 1 Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups. Lancet 1997;349:825-832. 2 Powell EE, Edwards-Smith CJ, Hay JL, Clouston AD, Crawford DH, Shorthouse C, et al. Host genetic factors influence disease progression in chronic hepatitis C. Hepatology 2000;31:828-833. 3 Day CP. Genetic studies to identify hepatic fibrosis genes and SNPs i n human populations. Methods Mol Med 2005

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The mysterious relation between inflammation and prostate cancer

neoplastic cells [ 28 ]. Other studies have reported that high expression of chemokine receptors may be necessary to activate cancer progressing signals. For instance, advanced aggressive PC cells express higher levels of CCR2 compared to less-aggressive gland cells, and they also show increase in metastatic capacity compared to localized PC [ 33 ]. Furthermore, increased CXCL8 and CCL2 levels in serum have been shown to be potential prognostic markers of a highly progressive PC [ 34 , 35 ]. Therefore, the role of chemokines in PC is very significant. 3 Cytokines

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