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Genetic Markers Associated with Power Athlete Status

and vertical jump performance. All these observations implicate that rs41274853 SNP may be associated with sprint/power athletes status, but without more comprehensive studies and confirmations of the trends in allele and genotype frequencies, it will be rather a potential than a true marker. 2) Markers involved in the inflammatory and repair reactions in skeletal muscle during and after exercise Inflammation may serve as a mechanism promoting skeletal muscle repair and hypertrophy. The inflammation processes are accompanied by upregulation of interleukins

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Interactions Between COL5A1 Gene and Risk of the Anterior Cruciate Ligament Rupture

( Wenstrup et al., 2006 ). In addition, mutations within COL5A1 were implicated in Ehlers Danlos syndrome ( Malfait et al., 2010 ; Myllyharju and Kivirikko, 2001 ), a condition characterized by joint hypermobility. The Bst UI RFLP (rs12722) is a common C to T single nucleotide polymorphism (SNP) within the COL5A1 3′ untranslated region which may alter COL5A1 messenger RNA (mRNA) stability ( Laguette et al., 2011 ). Previous studies identified the Bst UI restriction fragment length polymorphism (RFLP) to be associated with chronic Achilles tendinopathy ( Mokone et

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Impact of the Polymorphism Near MC4R (rs17782313) on Obesity- and Metabolic-Related Traits in Women Participating in an Aerobic Training Program

al., 2008 ; Thorleifsson et al., 2009 ). However, it still remained to be established whether the described relationship of this polymorphism with a higher BMI is related to the MC4R’s role in obesity, or whether it has an independent role in regulation of body weight. Of interest is that this SNP is not only associated with a higher BMI, but also with increased height, which is consistent with the phenotype of individuals with mutations within the MC4R coding region ( Loos et al., 2012 ). We hypothesized that rs17782313 may be a marker of the casual genetic

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Polygenic Study of Endurance‐Associated Genetic Markers NOS3 (Glu298Asp), BDKRB2 (‐9/+9), UCP2 (Ala55Val), AMPD1 (Gln45Ter) and ACE (I/D) in Polish Male Half Marathoners

Introduction The probability of becoming an elite athlete is influenced by genetic factors ( Eynon et al., 2013 ). A PubMed base has publicized that at least 120 genetic markers are linked to elite athlete status (Ahmetov and Fedotovskaya, 2015). However, only few of genes have been associated with endurance performance (Ahmetov and Fedotovskaya, 2015). Among them genetic markers such as ACE ( Montgomery et al., 1998 ), AMPD1 ( Ginevičienė et al., 2014 ; Rubio et al., 2005 ), NOS3 (Drozdovska et al., 2009; Saunders et al., 2006 ), UCP2 ( Buemann et

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