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Risk for stroke and chronic kidney disease in patients with sleep apnea syndrome and heart failure with different ejection fractions

artery disease; HF; arrhythmias; stroke; nasal septum deviation; polyposis; hypertrophic uvula; smoking status and SAS score. The somnographic recording was done with Stardust Respironics and Porti. Several parameters were measured: the number of central, obstructive, mixed apnea and hypopnea; both the total number of events and the number of events per hour; the apnea–hypopnea index (AHI); the desaturation index; the mean saturation; the lowest saturation; and the longest desaturation period. The somnographic recording was performed and scored manually according to

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Awake sedation thoracoscopy for the diagnosis of malignant mesothelioma: a service review

(VATS). Safety analysis involved determining the rate of major and minor complications. In addition, we analysed the 6-point patient-perceived comfort score, which was introduced to the service in 2013, to examine how well the procedure was tolerated. Results This service review included 104 consecutive patients who underwent thoracoscopy over a 5-year period from April 2010 to April 2015. Seventy-one were male (68%), and 33 were female (32%). The age range varied widely from 36 to 92 years (mean 70.4 years, median 71 years). Thoracoscopy was performed on the

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Asthma–COPD–Bronchiectasis combination: an unstudied triplet

, Holland SM, Prevots R. Trends in bronchiectasis among Medicare beneficiaries in the United States, 2000 to 2007. Chest 2012;142: 432–439. 22302301 10.1378/chest.11-2209 Seitz AE Olivier KN Adjemian J Holland SM Prevots R Trends in bronchiectasis among Medicare beneficiaries in the United States, 2000 to 2007 Chest 2012 142 432 439 3 Padilla-Galo A, Olveira C, Fernández de Rota-Garcia L, Marco-Galve I, Plata AJ, Alvarez A, et al. Factors associated with bronchiectasis in patients with uncontrolled asthma; the NOPES score: A study in 398

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Sleep apnea syndrome and heart failure—mechanisms and consequences

with continuous positive airway pressure. Journal of Cardiac Failure 2010;16(2): 164–174. 20142029 10.1016/j.cardfail.2009.08.006 Chowdhury M Adams S Whellan DJ Sleep-disordered breathing and heart failure: Focus on obstructive sleep apnea and treatment with continuous positive airway pressure Journal of Cardiac Failure 2010 16 2 164 174 11 Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, et al. Rules for scoring respiratory events in sleep: Update of the 2007 AASM manual for the scoring of sleep and associated events

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Decreased plasma epidermal growth factor (EGF) levels in patients with severe chronic obstructive pulmonary disease

bronchoalveolar lavage levels of EGF ( 21 ). Sputum HB-EGF expression was significantly increased in patients with COPD compared with nonsmokers and smokers without COPD. There was a significant positive correlation between sputum HB-EGF and COPD assessment test (CAT) score. HB-EGF expression was significantly increased in the lung tissue samples of patients with COPD and associated with collagen deposition and N- and E-cadherin, and vimentin expression. In vitro, HB-EGF promoted collagen production in lung fibroblasts. Moreover, HB-EGF induced the EMT process through induction

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Prognosing a severe course of asthma in children following the study of endothelial function

propensity score matching. The quality of the elaborated model was tested using the percent concordant (PC). This figure is equal to the fraction of observations that were correctly reclassified into separate subgroups of the dependent index using the logistic regression equation. The closer this indicator to 100%, the higher the quality of the resulting model is. Mathematically, the logistic regression model is represented as the dependence of the logarithm of the chance of the onset of the predicted event (logit) on the linear combination of factor variables

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