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Emese Rapolti, Theodora Benedek, István Kovács, Szilamér Korodi, Zsuzsanna Suciu, Sebastian Condrea, Edvin Benedek, András Mester and Imre Benedek

Abstract

Introduction: Peripheral artery disease, a frequent consequence of atherosclerosis, is usually associated with concomitant ischaemic coronary artery disease and with a high rate of cardiovascular mortality.

Material and methods: The study population consisted of 24 patients, admitted to our clinic with peripheral artery disease, 10 of them with critical limb ischaemia. In all cases, cardiovascular risk factors, left ventricular dysfunction and ejection fraction were analyzed. Peripheral Multislice Angio CT examination was used to determine the TASC class and to assess the peripheral arterial lesions. The Coronary Calcium Score and the Syntax Score were determined with angio CT of the coronary arteries.

Results: Patients were between 39 and 84 years of age, and 54% were in Fontaine class 2B, 21% in Fontaine class 3 and 25% in Fontaine class 4. 12.5% of patients presented TASC class A, 33.3% TASC class B, and 54.2% TASC class C. Coronary Calcium Scores were between 0 and 100 in 16.6% of patients, between 100 and 400 in 41.8%, and >400 in 41.6% of patients. The SYNTAX Score was <22 in 54% of patients, between 22 and 32 in 37.5%, and >32 in 8.5% of patients. A significant correlation was found between the Coronary Calcium Score and the SYNTAX Score (r = 0.82, p = 0.03). The Syntax Score was 22.43 ± 3.2 in TASC A patients, 26.2 ± 5.4 in TASC B patients, 32.1 ± 2.3 in TASC C patients (p = 0.005).

Conclusions: The severity of coronary artery disease characterized by the Syntax Score, by the presence of left main stenosis and segmental left ventricular hypokinesis presents significant correlation with the severity of peripheral artery disease, characterized by the TASC classification.

Open access

Alina Cordunean, Roxana Hodaş, Sorin Pop, Nora Rat, Laura Jani, Alexandra Stănescu, Imre Benedek and Theodora Benedek

C, Callister TQ, Browner WS. What does my patient's coronary artery calcium score mean? Combining information from the coronary artery calcium score with information from conventional risk factors to estimate coronary heart disease risk. BMC Med . 2004;2:31. 11. Moses JW1, Leon MB, Popma JJ et al. Sirolimus-Eluting Stents versus Standard Stents in Patients with Stenosis in a Native Coronary Artery. N Engl J Med . 2003;349(14):1315-23. 12. Wiebe J, Nef HM, Hamm CW. Current status of bioresorbable scaffolds in the treatment of coronary artery disease

Open access

Mihai Roman, Radu Prejbeanu, Andrei-Marian Feier, Octav Russu, Adrian Todor, Vlad Predescu, Bogdan Codorean, Tiberiu Bățagă and Radu Fleaca

ligament injuries. Clin Orthop Relat Res. 1985;(198):43-49. 4. Mitsou A, Vallianatos P, Piskopakis N, et al. Anterior cruciate ligament reconstruction by over-the-top repair combined with popliteus tendon plasty. J Bone Joint Surg Br. 1990;72:398-404. 5. Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD. Knee Injury and Osteoarthritis Outcome Score (KOOS) - development of a selfadministered outcome measure. J Orthop Sports Phys Ther. 1998;28:88-96. 6. Irrgang JJ, Anderson AF, Boland AL, et al. Development and validation

Open access

Roxana Hodaş, Sorin Pop, Diana Opincariu, Nora Rat, Laura Jani, Alexandra Stanescu, Edvin Benedek, Imre Benedek, Theodora Benedek and Monica Chitu

Abstract

Background: Epicardial fat has been recently identified as a major player in the development of the atherosclerotic process.

Study aim: The aim of this study was to correlate the epicardial fat volume (EFV), determined by Multisclice CT, and the severity of the coronary lesions, expressed by the Coronary Calcium Score (CCS) and Syntax Score (SxS) in patients with established coronary artery disease (CAD).

Material and methods: One-hundred-twenty-six patients underwent Multisclice 64 CT assessment of coronary lesions and epicardial fat quantification. Calculation of CCS was performed on all the three coronary vessels and was followed by determination of SxS according to guidelines. The patients were divided into 2 groups: Group 1 – patients with CCS >400 (n = 26), and Group 2 — patients with CaS <400 (n = 100).

Results: The mean age of the study population was 65.32 years for Group 1 and 54 years for Group 2 (p <0.0001). However, patients >65 years of age had a high CCS in a more significant extent than younger patients (50% in Group 1 vs. 17% in Group 2, p = 0.0115). Female gender was recorded in 48% of cases in Group 2 and in 19% of cases in Group 1 (p = 0.008). Several factors were identified in a higher extent in the group with high CCS as compared with the group with low CCS, such as the presence of significant stenosis (>50%) of the left anterior descending artery (LAD) (46% vs. 9%, p <0.0001), the presence of multi-vessel coronary disease (50% vs. 5%, p <0.0001) and a high SxS, above 23 (23% vs. 4%, p = 0.006). The epicardial fat volume was 117.81 ± 40.4 ml (95% CI: 97.98–138.2 ml) in Group 2 and 89.77 ± 37.7 ml (95% CI: 80.4–101.5 ml) in Group 1 (p = 0.0033).

Conclusions: Epicardial fat volume could represent a new imaging-derived biomarker, useful for classification of the severity of coronary artery disease, increased values of EFV being associated with other biomarkers of disease severity, such as calcium score.

Open access

Octav Russu, Tiberiu Bățagă, Marcela Todoran, Emilian Ciorcila, Teodora Maria Denisa Popa, Andrei-Marian Feier, Radu Prejbeanu, Radu Fleaca, Mihai Roman, Tudor Sorin Pop and István Gergely

-incision and endoscopic techniques for reconstruction of the anterior cruciate ligament. J South Orthop Assoc . 1996;52:87-95. 21. Logan JS, Elliot RR, Wilson AJ. TransLateral ACL reconstruction: a technique for anatomic anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc . 2012;207:1289-1292. 22. Roos EM, Lohmander LS. The Knee injury and Osteoarthritis Outcome Score KOOS: from joint injury to osteoarthritis. Health Qual Life Outcomes . 2003;1:64. 23. Collins NJ, Misra D, Felson DT, Crossley KM, Roos EM. Measures of knee

Open access

Octav Russu, Tiberiu Bățagă, Andrei-Marian Feier, Radu Prejbeanu, Radu Fleaca, Mihai Roman and István Gergely

tibial tunnel. Arthroscopy. 2013;29:1195-1200. 9. Briggs KK, Lysholm J, Tegner Y, Rodkey WG, Kocher MS, Steadman JR. The reliability, validity, and responsiveness of the Lysholm score and Tegner activity scale for anterior cruciate ligament injuries of the knee: 25 years later. Am J Sports Med. 2009;37:890-897. 10. Hussein M, van Eck CF, Cretnik A, Dinevski D, Fu FH. Individualized anterior cruciate ligament surgery: a prospective study comparing anatomic single- and double-bundle reconstruction. Am J Sports Med. 2012

Open access

Mirabela Morariu, Diana Opincariu and Alexandra Stănescu

. 2008;4(2):315-324. 9. Greenland P, Bonow RO, Brundage BH, et al. ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Clinical Expert Consensus Task Force (ACCF/AHA Writing Committee to Update the 2000 Expert Consensus Document on Electron Beam Computed Tomography) developed in collaboration with the Society of Atherosclerosis Imaging and Prevention and the Society

Open access

Simona Cernea, Andrada Larisa Roiban and Emőke Both

;2012:103472. 24. Sun X, Luo L, Zhao X, Ye P. Controlling Nutritional Status (CONUT) score as a predictor of all-cause mortality in elderly hypertensive patients: a prospective follow-up study. BMJ Open . 2017;7:e015649. 25. Chen QJ, Qu HJ, Li DZ, et al. Prognostic nutritional index predicts clinical outcome in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Sci Rep . 2017;7:3285. 26. Dalvi PS, Yang S, Swain N, et al. Long-term metabolic effects of malnutrition: Liver steatosis and insulin

Open access

Ioan Ferenț, András Mester, Monica Chițu, Annabella Benedek, Mihaela Rațiu, Roxana Hodas and Imre Benedek

, Benedek I. Analysis of coronary plaque morphology by 64 multislice computed tomography coronary angiography and calcium scoring in patients with type 2 diabetes mellitus. Acta Endocrinologica . 2011;7:59-68. 6. Benedek I, Chitu M, Kovacs I, Bajka B, Benedek T. Incremental Value of preprocedural Coronary Computed Tomographic Angiography to classical Coronary Angiography for prediction of PCI complexity in left main stenosis. World Journal of Cardiovascular Disease . 2013;9:573-580. 7. Benedek T, Jako B, Benedek I. Plaque quantification by coronary CT and

Open access

Pal Fodor, Radu Prejbeanu, Vlad Predescu, Bogdan Codorean, Radu Fleaca, Mihai Roman, Adrian Todor, Octav Russu and Tiberiu Bățagă

Abstract

Introduction: Bone marrow lesions (BMLs) are commonly described as magnetic resonance imaging (MRI) findings associated with stress injuries or trauma. The presence of BMLs closely correlates with pain and rapid joint deterioration. Case presentation: A 51-year-old healthy man presented to our clinic with severe knee pain due to BMLs. After 3 months of conservative treatment, arthroscopy and subchondroplasty (SCP) of the medial femoral condyle was performed. The IKDC (International Knee Documentation Committee) score improved from 39.9 to 66.7 at 6 months, and to 87.4 at 1 year after surgery. The KOOS (Knee Injury and Osteoarthritis Outcome) score improved from 38.5 to 77.7 at 6 months, and to 92.6 at 1 year after surgery. The Tegner Lysholm score improved from 23 to 80 at 6 months, and to 95 at 1 year after surgery. Conclusion: SCP may provide a viable approach to reduce pain associated with BML, with minimal risk of significant complications.