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studies and pilot trials of PTX[ 14 - 16 ] suggested that pentoxifylline reduced plasma TNF- α and IL-6, ALT and AST levels but there is scarcity of data to observe improvement of NAFLD activity score (NAS) and fibrosis score in patients with nonalcoholic steatohepatitis (NASH). The aim of this study was to observe the effect of pentoxifylline on histological activity and fibrosis of Bangladeshi nonalcoholic steatohepatitis patients. Materials and methods This study was conducted from August 2014 to December 2015 as an open label Randomized Control Trial (RCT). The

Liver Disease (MELD) is a validated chronic liver disease (CLD) severity scoring system that includes serum bilirubin, serum creatinine, and the international normalized ratio (INR). An increasing MELD score is associated with progression of hepatic dysfunction, severity and three-month mortality risk.[ 5 ] MELD is also used to prioritize patients on liver transplant waiting list. It is considered better than the Child-Turcotte-Pugh (CTP) score, in part, because of the inclusion of creatinine, which reflects the prognostic impact of renal function.[ 6 ] Evangelos et

dysfunction and increased risk of vascular malformation. [ 2 ] Since GI diseases are common in ESRD patients, multiple studies have been conducted to study the endoscopic findings in this population. Most common reason for endoscopic evaluation has been UGIB. [ 2 , 4 ] Several scoring systems have also been developed to classify patients with UGIB according to their outcome. One such scoring system is the Glasgow Blatchford bleeding Score (GBS), a well-established tool to stratify patients in dire need of intervention from UGIB on the basis of their history, physical

disease is the Framingham risk score (FRS). According to the National Institutes of Health, the patients having chronic kidney disease are considered as having a coronary heart disease risk equivalent, meaning that they are primarily patients with a 10-year risk for myocardial infarction or coronary death >20%, despite without known coronary heart disease. [ 8 ] Metabolic acidosis, a common condition and an important manifestation of the late stage of chronic kidney disease, leads to clinically significant consequences, including bone disease disorders, protein energy

, lethargy, impaired intellectual ability, and so on in end-stage coma (with or without response to stimuli) and later death in severe cases. [ 4 , 5 , 6 , 7 ] The neuropsychological peculiarity can be revealed by the use of psychometric tests, for instance, neuropsychological tests such as Halstead-Reitan (H-R) score and Child-Pugh score or other psychometric tests. [ 8 , 9 , 10 ] There is no gold standard test to diagnose HE due to the personal peculiarities of each case. That is why physicians mostly rely on their personal experiences, equipment availability, and

Introduction Brain dysfunction is a frequent complication of sepsis even in cases of extra-cranial origin and is related to several underlying mechanisms. Encephalography (EEG) seems to be a useful tool in detecting the presence of encephalopathy in patients with sepsis. Although EEG is not a specific test, it is sensitive and can detect abnormalities even when clinical neurologic examination is normal. The aim of this study was to document the EEG abnormalities and search for correlations between EEG findings and commonly used severity and prognostic scores

Introduction Liver cir rhosis (LC) is a common gastroenterological pathology among adults. Its aetiological factors are: alcohol abuse, hepatitis B infection, hepatitis C infection, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis and others.[ 1 , 2 ] Cirrhosis with multiple-aetiologies are more susceptible of developing multiple organ failures, predominantly kidney, brain, heart and others.[ 1 , 3 ] This disease can be classified using several methods and these cases will be focusing on Halstead-Reitan and Child-Pugh score classification

patient visits, and is therefore not easily applicable to large patient populations. In recent years, a number of serum-based fibrosis tests have been developed and validated. Many studies have reported reasonable performance characteristics and good agreement with biopsy or elastography data.[ 4 , 5 ] With the advent of electronic medical record systems, fibrosis scores can be easily calculated after extracting the pertinent test results for each patient. This process does not require additional patient visits, and can be applied to large patient cohorts. As such, EMR

complications has been observed.[ 7 - 8 ] In the past few years, several biochemical indices have been proposed for the noninvasive evaluation of liver fibrosis in patients with chronic viral hepatitis and normal renal function. However, little data is available regarding this issue among the ESRD population.[ 9 , 10 , 11 ] To minimize the need of liver biopsy and overcome its aforementioned limitations, there is a need to use tests that are less invasive and relatively easier to perform. We studied the diagnostic accuracy of two scoring systems, aspartate aminotransferase

considered a major risk factor carrying an increased morbidity and mortality in cirrhotic patients undergoing any kind of surgery, as they can often decompensate because of both anesthesia and surgery. [ 12 , 13 , 14 , 15 ] Diverse scores and indexes have been used for predicting the outcome of patients preoperatively, among which the American Society of Anesthesiologists (ASA) score and the age-adjusted Charlson Comorbidity Index (aaCCI) are the most validated for the pre- and perioperative evaluation. [ 14 , 15 , 16 ] However, in cirrhotic patients, the Child