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Nikolina Basic-Jukic, Bozidar Vujicic, Josipa Radic, Dragan Klaric, Zeljka Grdan, Goran Radulovic, Klara Juric, Karmela Altabas, Marko Jakic, Valentina Coric-Martinovic, Ivana Kovacevic-Vojtusek, Marijana Gulin, Nikola Jankovic, Dragan Ljutic and Sanjin Racki

Abstract

Introduction. Residual diuresis (RD) is an important predictor of mortality and cardiovascular (CV) deaths in peritoneal dialysis (PD) patients, and contributes more to overall survival compared to PD clearance. In this study we investigated the correlation between RD and CV outcomes in PD patients.

Methods. A total of 190 PD patients from 13 dialysis centers, a national representation, were included in this analysis. Biomarkers of anemia, nutritional status [malnutrition inflammation score (MIS), subjective global assessment (SGA), serum albumin, anthropometric measurements including body mass index (BMI)], dialysis dose (Kt/V) and laboratory measurements were determined. RD was estimated using the volume of daily urine.

Results. There were 78(41.05 %) females and 112 (58.95 %) males; aged 57.35±14.41 years, on PD for 24.96±24.43 months. Fifty-six patients had diabetes type II (44 as primary kidney disease). The mean RD was 1170±673.6 ml (range 0-3000 mL). Statistically significant correlations between RD and BMI, hip circumference, time on PD, Kt/V, MIS, SGA, erythrocytes (E), Hemoglobin (Hb), PTH, and serum albumin were observed.

Conclusions. We demonstrated a significant correlation between RD and MIS score, SGA, anthropometry and albumin. Every effort should be invested to maintain RD for as long as possible to achieve optimal treatment results and to decrease CV mortality in PD population.

Open access

Aysegul Kahraman, Hakan Akdam, Alper Alp, Mustafa Ahmet Huyut, Cagdas Akgullu, Tuba Balaban, Fadime Dinleyen, Aynur Topcu, Husniye Gelmez, Nevin Atakan, Harun Akar and Yavuz Yenicerioglu

factors for higher mortality at the highest levels of spkt/V in haemodialysis patients. Nephrol Dial Transplant 2003; 18: 1339-1344. 24. Agroyannis B, Fourtounas C, Tzanatos H, et al. Relationship between interdialytic weight gain and acid-base status in hemodialysis by bicarbonate. Artif Organs 2002; 26: 385-387. 25. Janardhan V, Soundararajan P, Rani NV, et al. Prediction of Malnutrition Using Modified Subjective Global Assessmentdialysis Malnutrition Score in Patients on Hemodialysis. Indian J Pharm Sci 2011; 73: 38

Open access

Aikaterini Balaska, Dimitris Pistolas, Maria Koukoulaki, Dimitris Alassas, Spiros Drakopoulos, Ioannis Kaklamanos, Gerasimos Bonatsos and Kostantinos Birbas

Abstract

Introduction. This study was undertaken to compare and evaluate the heath-related quality of life (HRQOL) in Greek adult transplant recipients before and 2 years after successful renal transplantation (RT). The SF-36 survey score was used. Methods. Eighty-five Greek hemodialysis patients underwent RT at the Transplant Unit of Evangelismos General Hospital of Athens, including 44 men and 41 women (mean age 43.8 years; range 21-59 years). The scale scores of a Greek version of the SF-36 survey were compared between the transplant and the hemodialysis patients. We also examined the relationships of the scale scores with the patients′ age and the type of donor. Results. According to the SF-36 health survey, transplant recipients had better results for general health perception (p≤0.001), role-physical functioning (p≤0.01), role-emotional functioning (p≤0.01), and vitality (p≤ 0.01). In addition, the scale score of physical functioning, general health and vitality of the patients who were younger than 30 years at the time of transplantation were significantly higher than those of the patients who were older than 30 years, while the scores of bodily pain, general health, and physical functioning were significantly lower in cadaveric graft recipients compared with living-related recipients. Conclusions. The SF-36 health survey is a validated and comprehensive instrument for evaluating renal transplant patients′ HRQOL. Our data demonstrated an improvement in HRQOL in renal transplant patients 2 years after successful renal transplantation. The data also confirmed that the recipients′ age at transplantation and the type of donor were important factors affecting the HRQOL.

Open access

Nada Pop-Jordanova and Momir Polenakovic

Abstract

Introduction. The concept of alexithymia means dysfunction in emotional awareness, social attachment, and interpersonal relating. The study was performed to evaluate the alexithymia construct in patients treated with chronic maintenance haemodialysis.

Methods. TAS-20 was applied as a measure of alexithymia to a group of 230 patients, mean age 55.5±13.5 years, recruited from three dialysis centers.

Results. The results obtained showed that 50% of patients were alexithymic, and 18% had possible alexithy-mia. A small positive correlation was shown between age and obtained scores for alexithymia (r=0.025). Duration of dialysis also positively influenced the alexithymia scores (r=0.013). In addition, the duration of dialysis was significantly influenced by age (ANOVA 0.004, p<0.05). Factors analysis showed that F1 and F2 were not influenced by age or duration of dialysis. Only factor F3 (externally oriented thinking) was very perceptible and influenced by the age and the duration of dialysis (ANOVA p=0.016; <0.05).

No significant differences in scores between males and females were obtained. Only F1 was higher in males (p<0.05). The scores obtained for alexithymia were compared between healthy population and cancer and dialysis patients. Patients with chronic diseases were more alexithymic than healthy people (p< 0.05).

Conclusions. The alexithymia construct is a permanent personality trait related to neurobiological brain specifics. An alexithymia construct can influence the prognosis and outcome of dialysis patients as well as of other diseases. The psychological support for mediating alexithy-mia should be included in the therapeutic protocols, especially for end-stage renal diseases.

Open access

Nada Pop-Jordanova and Momir Polenakovic

Abstract

Researchers confirmed that depression and anxiety are two common comorbid disorders in chronic kidney patients. The aim of our study was to screen the level of depression and anxiety in a group of end-stage kidney diseases treated with hemodialysis. The evaluated sample comprised 230 participants; 110 females (mean age 55.5±13.5 years), and 120 males (mean age 54.5±14.3 years). The mean duration of maintenance dialysis was 8.3±5.8 years (from 0.5 to 24 years). Patients were selected randomly from three dialysis centers in R. Macedonia. As psychometric instruments Beck Depression Inventory (BDI) and scores from Minnesota Multiphasic Personality Inventory (MMPI-201) were used. Our study confirmed that majority of evaluated dialyzed patients are depressed and anxious in different level, but unfortunately the mental problems are frequently unrecognized. We suggested some response measures for management of these conditions in order to avoid risks for complications as well of suicide.

Open access

Morteza Qaribi, Ali Abdolrazaghnejad, Reza Shahmirzaei and Abdolghader Pakniyat

renal oxidative stress after coronary angiography more effectively than oral N-acetylcysteine. Heart and vessels 2011; 26(5): 465-472. 11. Safari S, Yousefifard M, Hashemi B, et al. The value of serum creatine kinase in predicting the risk of rhabdomyolysis- induced acute kidney injury: a systematic review and meta-analysis. Clinical and experimental nephrology 2016; 20(2): 153-161. 12. Safari S, Yousefifard M, Hashemi B, et al. The Role of Scoring Systems and Urine Dipstick in Prediction of Rhabdomyolysis- induced Acute Kidney Injury

Open access

Ingrid Prkacin, Petra Vrdoljak, Gordana Cavric, Damir Vazanic, Petra Pervan and Visnja-Nesek Adam

the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT): a risk score to dentify those at high-risk. Hypertension 2011; 29(10): 2004-2013. doi: 10.1097/HJH.0b013e32834a8a42. 10. Prkacin I, Ozvald I, Cavric G, et al. Importance of urinary NGAL, serum creatinine standardization and estimated glomerular filtration rate in resistant hypertension. Coll Antropol 2013; 37 (3): 821-825. 11. Denolle T, Chamontin B, Doll G, et.al. Management of resistant hypertension: expert consensus statement from the French Society of Hypertension, an

Open access

Katerina Markoska, Jelka Masin-Spasovska, Momir Polenakovic and Goce Spasovski

, Vupputuri S, Shoham DA, et al. SCreening for Occult REnal Disease (SCORED): a simple prediction model for chronic kidney disease. Arch Intern Med 2007; 167(4): 374-381. 37. Boulware LE, Jaar BG, Tarver-Carr ME, et al. Screening for proteinuria in US adults: a cost-effectiveness analysis. JAMA 2003; 290(23): 3101-3114. 38. Mischak H, Ioannidis JP, Argiles A, et al. Implementation of proteomic biomarkers: making it work. Eur J Clin Invest 2012; 42(9): 1027-1036.