, Wesson DE, Wolman SL, Stewart S, Whitewell J, et al. Nutritional assessment: a comparison of clinical judgement and objective measurements. N Engl J Med 1982; 306: 969–72.
8. Kalantar-Zadeh K, Kopple JD, Block G. A malnutrition inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients. Am J Kidney Dis 2001; 38: 1251–63.
9. Tonelli M, Sacks F, Pfeffer M, Jhangri GS, Curhan G: Biomarkers of inflammation and progression of chronic kidney disease. Kidney Int 2005; 68: 237–45.
10. Kopple JD: Nutritional status as a
Valentina Risteska Nejashmikj, Snezana Stojkovska, Irena Kondova Topuzovska and Katarina Stavrikj
7. McIsaac WJ, Goel V, To T. Low DE. The validity of a sore throat score in family practice. CMAJ 2000;163:811–815.
8. Marjukka Makela Article ID: ebm00007 (038.020) EBM Guidelines, 27.04.2011, www.ebm-guidelines.com available at http://zdravstvo.gov.mk/wp-content/uploads/2015/08/Gusobolka-i-tonzilit.pdf
9. Teng CL, Tong SF, Khoo EM, Lee V, Zailinawati AH, Mimi O, et al. Antibiotics for URTI and UTI—prescribing in Malaysian primary care settings. Aust Fam Physician 2011;40:325–9.
10. Teixeira Rodrigues A, Roque F, Falcão A, Figueiras A
Krsto Grozdanovski, Zvonko Milenkovikj, Ilir Demiri, Katerina Spasovska, Marija Cvetanovska, Goran Rangelov, Velimir Saveski and Biljana Grozdanovska
-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996; 22(7): 707–710.
13. Hall KK, Lyman JA. Updated review of blood culture contamination. ClinMicrobiol Rev 2006; 19(4): 788–802.
14. Richter SS, Beekmann SE, Croco JL, et al. Minimizing the workup of blood culture contaminants: implementation and evaluation of a laboratory-based algorithm. J ClinMicrobiol2002; 40: 2437–2444.
15. Wildi K, Tschudin
Introduction: Opioid-free anesthesia (OFA) is a new anesthesiological technique, where the giving of opioids (fentanyl) is avoided in the intra- and post-operative period. This leads to reduction in the opioid-related side effects and lower pain scores in the postoperative period.
Materials and methods: In this randomized, single-blind clinical study, 60 patients scheduled for elective laparoscopic cholecystectomy were enrolled. Half of them (30 patients) received general balanced anesthesia with fentanyl (F group-FG), and the half received opioid-free general anesthesia (OFA group-OFAG). In the post-operative period, Visual Analogue Scale (VAS) scores were followed at rest and when coughing 1 hour, 4 hrs, 8 hrs, 12 and 24 hrs after surgery. Both groups were followed by opioid requirements in the postoperative period.
Results: In the postoperative period, patients in the fentanyl group (FG) have higher pain scores at rest and on coughing in all analyzed timeframes compared to patients from the OFA group, but statistically significant difference was approved 1 and 24 hours after surgery. In the OFA group 24 hours after surgery none of the patients reported pain at rest and when coughing number 7, 8, 9 and 10 according to the VAS pain score. The total opioid requirement in the postoperative period was significantly higher in the fentanyl group (FG) at rest and when coughing, compared to the OFA group.
Conclusion: Opioid-free anesthesia as a part of multimodal analgesia and a new anesthesiology technique is a safe procedure, where opioid-related negative effects in patients undergoing elective laparoscopic cholecystectomy are avoided..
Nada Pop-Jordanova, Jovanka Ristova and Sofija Loleska
Personality correlates in patients with eye diseases have bidirectional influence. It is possible that personality variables lead to behaviours that may influence the cause of eye problems, but the opposite is also possible, that eye problems could have a direct effect on personality.
The aim of this study was to evaluate personality traits in patients with glaucoma, diabetic retinopathy and cataract using the Eysenck Personality Questionnaire.
Obtained results showed similar personality profiles in patients with glaucoma, diabetic retinopathy and cataract. However, extraversion and neuroticism were higher in patients with diabetes, while the psychopathic traits are the highest in the group of cataract.
Age and gender of patients do not influence the scores obtained on the questionnaire confirmed with one way ANOVA. Not significant difference in parameters (tested with Student t-test) was obtained between groups.
It is proposed psychological evaluation to be included in the assessment of more serious eye diseases for helping patients to adjust and adapt to the condition and treatment.
Committee on Fetus and Newborn; American College of Obstetricians and Gynecologist Committee on Obstetric Practice. The Apgar Score. Pediatrics. 2015 Oct; 136(4): 819–22.
8. De Berins L, Sherratt DR, AbouZahr C, Van Lerbegrhe W. Skilled attendance for pregnancy, childbirth and postnatal care. Br Med Bull. 2003; 67: 39–57.
9. Yakoob MY, Ali MA, Ali MU, Imdad A, Lawn JE, Van Den Broek N et al. Tge effect of providing skilled birth attendance and emergency obstetric care in preventing stillbirths. BMC Public Health. 2011; 11: S7.
10. World Health
Marijan Bosevski, Irena Mitevska, Marica Pavkovic, Milka Klincheva, Emilija Trajkovska Lazarova, Emilija Velkova, Zlate Stojanoski, Nela Kostova, Savetka Paljoskovska Jordanova, Danica Petkoska, Mimi Mancheva, Aleksandra Gulevska, Marjan Baloski, Vasko Hadjiev, Gorjan Krstevski, Viktorija Kralevska, Ivica Bojovski, Mario Jovanovski, Vesna Nedelkovska and Atanas Gjorgievski
increases risk for venous thromboembolism. J Am Soc Nephrol. 2008 Jan; 19(1): 135–40.
8. Mulder FI, Candeloro M, Kamphuisen PW, Di Nisio M, Bossuyt PM, Guman N, Smit K, Büller HR, van Es N; CAT prediction collaborators; CAT-prediction collaborators. The Khorana score for prediction of venous thromboembolism in cancer patients: a systematic review and meta-analysis. Haematologica. 2019 Jan 3. pii: haematol.2018.209114. doi: 10.3324/haematol.2018.209114.
9. 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism. (2014). European Heart
Viktor Kamnar, Anastasika Poposka, Nenad Atanasov and Milena Bogojevska
Background: The aim of this study is to affirm the importance of operative treatment of severe dysplastic coxarthrosis through analysis of the results of implantation of total cementless endo-prothesis in patients with DDH Crowe types III and IV.
Patients and methods: This retrospective study involved 28 patients (30 hips) with dysplastic coxart-hrosis, in whom an implantation of cementless total hip endoprothesis was performed at the University Clinic for Orthopaedic Surgery in Skopje. In 26 of the patients the involvement was unilateral and in two patients it was bilateral. The inclusion criterion was radiographically proved severe hip dysplasia Crowe types III and IV. Twenty-one of the patients were female and 7 male, and age distribution was in an interval from 30 to 65 years. The ingrowth of the implant was evaluated using the clinical method, native radiographs and radioisotopic examination with Tc99m. The follow-up period lasted 5 years, and the results were evaluated using the Harris hip score system.
Results: 19 of the patients presented an excellent result of the operative treatment, there were 8 good results with persistent local pain 6 months postoperatively, in one case a surgical revision and reimplantation of the acetabular cup was performed, while one patient underwent a surgical revision and reimplantation of the femoral stem and in another patient there was nonunion at the place of the subtrochanteric osteotomy. Full weight-bearing without the use of crutches was achieved 3 months postoperatively, and no serious early postoperative complications were registered in our patients.
Discussion and conclusions: In the majority of cases in whom a total hip replacement with cemen-tless endoprothesis is performed because of dysplastic coxarthrosis, a sufficient primary fixation both of the acetabular and the femoral component is achieved, unless one-third of the acetabular cup is left uncovered with bone stock. The problems of decreased muscle strength and limping are usually solved by means of physical therapy in a time period of 45 months.
Krsto Grozdanovski, Zvonko Milenkovikj, Ilir Demiri, Katerina Spasovska, Marija Cvetanovska, Velimir Saveski and Biljana Grozdanovska
(Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 1996; 22(7): 707–10.
12. Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 1993; 270: 2957–2963.
13. Shankar-Hari M, Harrison DA, Rubenfeld GD, Rowan K. Epidemiology of sepsis and septic shock in critical care units: comparison between sepsis-2 and
Dragana Petrovska-Cvetkovska, Natalija Dolnenec-Baneva, Dijana Nikodijevik and Tatjana Chepreganova-Changovska
. Progresion in acute stroke: Value of the initial NIH stroke scale score on patients stratification in future trials. Stroke. 1999; 30: 1208–1212.
12. Baird AE, Dasche J, Connor A, et al. Comparision of retrospective and prospecive measurements of the national institutes of health stroke scale. Cerebrovasc Dis. 2000; 10: 80–81.
14. Adams H. Handbook of cerebrovascular disease. New York: Dekker; 1996
15. Abilleira S, Montaner J, Molin C, et al. Matrix metalloproteinase-9 contretation after spontaneous intracerebral hemorrhage. J Neurosurg 2003; 99: 65–70.
16. Leira R