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Jelena Perić, Branislav Lekić, Vesna Reljić, Lana Ćirković and Dušan Škiljević

Abstract

Cutaneous larva migrans (CLM) is a parasitic skin disease caused by the accidental percutaneous penetration and subsequent intraepidermal migration of larvae of various nematode parasites of the hookworm family. The hookworms responsible for CLM are spread worldwide, but the infection occurs mostly in tropical and subtropical climates. Nowadays, because of ever increasing foreign travel, the disease is no longer confined to these areas. Moreover, a significant increase of autochthonous cases in southern Europe has been observed in recent years. We report two new patients from Serbia who acquired CLM, none of them having traveled abroad. As the recommendations for the treatment of CLM are not uniform, two different treatment modalities were applied in these patients, both with an excellent response.

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Stoyan Ivanov Pavlov, Irina Ivanova Ivanova, Hristo Boychev Popov, Maria Angelova Tzaneva and Peter Ivanov Ghenev

J. Celiac disease associated with cutaneous sarcoidosic granuloma. Rev Med Interne. 1997;18(12):975–8. 11. Reunala T, Collin P. Diseases associated with dermatitis herpetiformis. Br J Dermatol. 1997;136(3):315–8. 12. Pagaltsos AS, Kumar PJ, Willoughby JM, Dawson AM. In-vitro inhibition of leucocyte migration by sarcoid spleen suspension in coeliac disease and dermatitis herpetiformis. Lancet. 1971;298(7735):1179–81. 13. Vaalamo M, Kariniemi AL, Shapiro SD, Saarialho-Kere U. Enhanced expression of human metalloelastase (MMP-12) in cutaneous

Open access

Marina Jovanović

;155:1006-12. 13. Roger France FH. Case mix use in 25 countries: a migration success but international comparisons failure. Int J Med Inf 2003;70:215-9. 14. Hensen P, Furstenberg T, Luger TA, Steinhoff M, Roeder N. Case mix measures and diagnosis-related groups: opportunities and threats for inpatient dermatology. J Eur Acad Dermatol Venereol 2005;19:582-8.

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Slobodan Stojanović, Snežana Brkić, Marina Jovanović and Nada Vučković

mastocytosis: a consensus proposal. Leuk Res 2001;25(7):603-25. 12. Akin C, Valent P, Escribano L. Urticaria pigmentosa and mastocytosis: the role of immunophenotyping in diagnosis and determining response to treatment. Curr Allergy Asthma Rep 2006;6:282-8. 13. Marone G, Florio G, Petraroli A, Triggiani M, de Paulis A. Human mast cells and basophils in HIV-1 infection. Trends Immunol 2001;22(5):229-32. 14. de Paulis A, Florio G, Prevete N, et al. HIV-1 envelope gp41 peptides promote migration of human Fc epsilon RI+ cells and

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Predrag Štilet and Miloš D. Pavlović

angiogenesis by disrupting endothelial cell migration and tube formation. J Exp Ther Oncol 2008;7:173-82. 16. Hasegawa K, Namekawa SH, Saga Y. MEK/ERK signaling directly and indirectly contributes to the cyclical self-renewal of spermatogonial stem cells. Stem Cells 2013;31:2517-27.

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Rumyana Yankova, Magdalina Gyurova and Donka Brambarova

migration of Langerhans cells. J Invest Dermatol. 2000;114(1):135-41. 59. Cozzi SJ, Le TT, Ogbourne SM, James C, Suhrbier A. Effective treatment of squamous cell carcinomas with ingenol mebutate gel in immunologically intact SKH1 mice. Arch Dermatol Res. 2013;305(1):79-83. 60. Wood ME, Vogel V, Ng A, Foxhall L, Goodwin P, Travis LB. Second malignant neoplasms: assessment and strategies for risk reduction. J Clin Oncol. 2012;30(30):3734-45.

Open access

Mirjana Paravina, Dragan Jovanović, Milenko Stanojević and Ljiljana Nikolić

, Hankins DP, Morris PJ, Austyn JM. Migration and maturation of Langerhans cells in skin transplants and explants. J Exp Med 1990;172:1483-93. 52. Weitzman S, Egeler RM. Langerhans cell histiocytosis: update for the pediatrician. Curr Opin Pediatr 2008;20:23-9. 53. Bechan GI, Egeler RM, Arceci RJ. Biology of Langerhans cell and Langerhans cell histiocytosis. Int Rev Cytol 2006;254:1-43. 54. Claudy AL. Les histiocytoses. In: Saurat JH. Dermatologie et venerologie. Paris: Masson; 1990. p. 475-87. 55. Martinović