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J Stilla, D Statelova, M Janickova, I Malachovsky, P Gengelova, J Jurkemik and K. Adamicova

tooth extraction socket, inhibits oral epithelial cell migration and promotes proliferation and adhesion to hydroxyapatite of oral bacteria, withou causing osteonecrosis, in mice. J Bone Miner Metab 2010 (28):165-175. 20. Hansen T, Kunkel M, Springer E, Walter C, Weber A, Siegel E, Kirkpatrick CJ. Actinomycosis of the jaws - histopathological study of 45 patients shows involvement in bisphophonate-associated osteonecrosis and infected osteoradionecrosis. Virchows Arch. 451:1009-1017, 2007 21. Gliklich R, Wilson J. Epidemiology of

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I. Zila and A. Calkovska

, Mortola JP. Hering-Breuer reflex in conscious newborn rats: effect of changes in ambient temperature during hypoxia. J Appl Physiol 1999; 87(5): 1656-61. Werner MF, Fraga D, Melo MC, Souza GE, Zampronio AR. Importance of the vagus nerve for fever and neutrophil migration induced by intraperitoneal LPS injection. Inflamm Res 2003; 52: 291-6. Schoener EP, Frankel HM. Effect of hyperthermia and PaCO 2 on the slowly adapting pulmonary stretch receptor. Am J Physiol 1972; 222(1):68-72. Žila I

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Junyu Liang, Weiqian Chen and Jin Lin

chromatin remodeling, promoter inactivation by binding to basal transcription factors, activation of accessory protein, activation and transport of transcription factors, oligomerization of activator protein, and epigenetic repression of genes or gene clusters. [ 10 ] Accumulating evidence has shown that lncRNAs participate in the process of inflammation, aberrant proliferation, migration, invasion and apoptosis, [ 11 , 12 , 13 , 14 ] and their roles in autoimmune diseases, such as systemic lupus erythematosus (SLE), sjogren syndrome, RA, multiple sclerosis, have

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Nan Ge, Jinlong Hu, Siyu Sun, Enqiang Linghu, Zhendong Jin and Zhaoshen Li

of the PPs to 3 cm on imaging (mainly EUS or CT) within 3 months. Procedure-related side effects included hemorrhage, stent migration into the cyst, cyst rupture with the use of cystotome, and severe infection. Reinterventions are endoscopic treatments performed after the initial EUS-guided stent placement. Failures include residual clinical symptoms, cyst reduction less than 50% in 3 months, or altered to open surgery. Hospital stay is calculated from the day of the initial EUS-guided drainage in hospital to the day of discharge. Devices Longitudinal

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Aurelia Enescu, F. Petrescu, P. Mitruţ, V. Pădureanu, Octavia Ileana Petrescu, Valeria Carmen Albu, Andreea Larisa Moraru and Anca Ştefania Enescu

Abstract

Hyponatremia is defined by a level of Na in serum below or equal to 136 mEq/L while in hepatic cirrhosis it is classically considered as relevant only at a level of Na below 130 mEq/L.

Hyponatremia frequently occurs in patients with end-stage hepatic disease. The frequency and severity are variable but it has been estimated that it occurs with a frequency of 57% in hospitalized patients with cirrhosis and in those on waiting lists for hepatic transplants. Signs and symptoms of hyponatremia are related to dysfunctions of the central nervous system, due to migration of the water from intravascular space to the brain cells, resulting in the occurrence of cerebral edema. Therapeutic options in hyponatremia are limited and are based on restriction of water consumption, exclusion of diuretics and vaptans. Hepatic transplant remains the only definitive treatment for end-stage hepatic diseases in which hyponatremia has occurred.

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Sarah P. Georgiadou, Konstantinos P. Makaritsis and George N. Dalekos

Abstract

Leishmaniasis is a vector-borne disease caused by protozoan parasites of the genus Leishmania. It is transmitted by phlebotomine female sand flies of the genera Phlebotomus and Lutzomyia in the old and new world, respectively. More than 20 well-recognized Leishmania species are known to infect humans and cause visceral (VL), cutaneous (CL) and mucocutaneous (ML) forms of the disease. Approximately 350 million people are at risk of contracting the disease and an estimated 1.6 million new cases occur annually. The disease mainly affects poor people in Africa, Asia and Latin America, and is associated with malnutrition, population migration, poor residency conditions, frail immune system and lack of resources. Previously, diagnosis of leishmaniasis relied mainly on invasive techniques of detecting parasites in splenic and bone marrow aspirates. Nevertheless, serological tests using the recombinant kinesin antigen (rK39) and molecular methods (polymerase chain reaction) are considered the best options for diagnosis today, despite problems related to varying sensitivities and specificities and field adaptability. Therapy of leishmaniasis ranges from local treatment of cutaneous lesions to systemic often toxic, therapy for disseminated CL, ML and VL. Agents with efficacy against leishmaniasis include amphotericin B, pentavalent antimonial drugs, paromomycin and miltefosine. No single therapy of VL currently offers satisfactory efficacy along with safety. This article provides a brief and updated systematic review on the epidemiology, diagnosis and treatment of this neglected disease.

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Eva Kiousi and Eirini Grapsa

, Fennell RS. Family behavior, adaptation and treatment adherence of nephrology patients. Pediatr Nephrol 1996;10:160-6. 26. Züllich D, Zimmering M, Keil T, Querfeld U. Migration background and patient satisfaction in a pediatric nephrology outpatient clinic. Pediatr Nephrol 2012;27:1309-16. 27. Davis JS, Zuber K. Implementing patient education in the CKD clinic. Adv Chronic Kidney Dis 2013;20:320-5. 28. Kutlugün AA, Arıcı M, Yıldırım T, Turgut D, Yılmaz R, Altındal M, et al. Daily sodium intake in chronic kidney disease

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Weili Men, Haijuan Xiao, Zhiping Yang and Daiming Fan

]. Prod Res 2011; 9: 7. Wang Y [Overview of talent agglomeration research] Prod Res 2011 9 7 2 Giannetti M. Skill complementarities and migration decisions. Labor 2001; 15: 1-32. 10.1111/1467-9914.00153 Giannetti M Skill complementarities and migration decisions Labor 2001 15 1 32 3 Kalling T. Knowledge management and the occasional links with performance. J Knowl Manag 2003; 3: 67-81. Kalling T Knowledge management and the occasional links with performance J Knowl Manag 2003 3 67 81 4 Cohen WM, Nelson RR, Walsh JP. Links

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Evelyn Nathalia, Madelaine Skolastika Theardy, Sharleen Elvira, Graciella Rosellinny, Andrew Steven Liyanto, Michael Putra Utama and Anton Sumarpo

Behav. 2012; 11 (4):444-451. 6. ALIFRAGIS P., LIAPI A., PARNAVELAS JG. Lhx6 regulates the migration of cortical interneurons from the ventral telencephalon but does not specify their GABA phenotype . J Neurosci. 2004; 24 (24):5643–5648. 7. FLANDIN P., ZHAO Y., VOGT D., JEONG J., LONG J., POTTER G., et al. Lhx6 and Lhx8 coordinately induce neuronal expression of Shh that controls the generation of interneuron progenitors . Neuron. 2011; 70 (5):939–950. 8. SUSSEL L., MARIN O., KIMURA S., RUBENSTEIN JL. Loss of Nkx2.1 homeobox gene function

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Ali Erfani Karimzadeh Toosi

tumor growth . Am J Pathol 2010; 177 : 1888-1900. 12. AMANN T, BATAILLE F, SPRUSS T, MUHLBAUER M, GABELE E, SCHOLMERICH J, KIEFER P, et al . Activated hepatic stellate cells promote tumorigenicity of hepatocellular carcinoma . Cancer Sci 2009; 100 : 646-653. 13. SANCHO-BRU P, JUEZ E, MORENO M, KHURDAYAN V, MORALES-RUIZ M, COLMENERO J, ARROYO V, et al . Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells . Liver International 2010; 30 : 31-41. 14. GUO HB, RANDOLPH M